PubMed

The transcriptional coactivator peroxisome proliferator activated receptor (PPAR)gamma coactivator-1 alpha and the nuclear receptor PPAR alpha control the expression of glycerol kinase and metabolism genes independently of PPAR gamma activation in human white adipocytes.

Mazzucotelli A, Viguerie N, Tiraby C, Annicotte JS, Mairal A, Klimcakova E, Lepin E, Delmar P, Dejean S, Tavernier G, Lefort C, Hidalgo J, Pineau T, Fajas L, Clément K, Langin D.

Diabetes. 2007 Oct;56(10):2467-75. Epub 2007 Jul 23.PMID: 17646210 [PubMed - indexed for MEDLINE]Related articlesFree article

Corepressors selectively control the transcriptional activity of PPARgamma in adipocytes.

Guan HP, Ishizuka T, Chui PC, Lehrke M, Lazar MA.

Genes Dev. 2005 Feb 15;19(4):453-61. Epub 2005 Jan 28.PMID: 15681609 [PubMed - indexed for MEDLINE]Related articlesFree article

Estrogen-related receptor alpha directs peroxisome proliferator-activated receptor alpha signaling in the transcriptional control of energy metabolism in cardiac and skeletal muscle.

Huss JM, Torra IP, Staels B, Giguère V, Kelly DP.

Mol Cell Biol. 2004 Oct;24(20):9079-91.PMID: 15456881 [PubMed - indexed for MEDLINE]Related articlesFree article

A dominant negative human peroxisome proliferator-activated receptor (PPAR){alpha} is a constitutive transcriptional corepressor and inhibits signaling through all PPAR isoforms.

Semple RK, Meirhaeghe A, Vidal-Puig AJ, Schwabe JW, Wiggins D, Gibbons GF, Gurnell M, Chatterjee VK, O'Rahilly S.

Endocrinology. 2005 Apr;146(4):1871-82. Epub 2005 Jan 20.PMID: 15661858 [PubMed - indexed for MEDLINE]Related articlesFree article

Thiazolidinediones and rexinoids induce peroxisome proliferator-activated receptor-coactivator (PGC)-1alpha gene transcription: an autoregulatory loop controls PGC-1alpha expression in adipocytes via peroxisome proliferator-activated receptor-gamma coactivation.

Hondares E, Mora O, Yubero P, Rodriguez de la Concepción M, Iglesias R, Giralt M, Villarroya F.

Endocrinology. 2006 Jun;147(6):2829-38. Epub 2006 Mar 2.PMID: 16513826 [PubMed - indexed for MEDLINE]Related articlesFree article

Peroxisome proliferator-activated receptor (PPAR) gamma coactivator-1 recruitment regulates PPAR subtype specificity.

Oberkofler H, Esterbauer H, Linnemayr V, Strosberg AD, Krempler F, Patsch W.

J Biol Chem. 2002 May 10;277(19):16750-7. Epub 2002 Mar 1.PMID: 11875072 [PubMed - indexed for MEDLINE]Related articlesFree article

Acquirement of brown fat cell features by human white adipocytes.

Tiraby C, Tavernier G, Lefort C, Larrouy D, Bouillaud F, Ricquier D, Langin D.

J Biol Chem. 2003 Aug 29;278(35):33370-6. Epub 2003 Jun 13.PMID: 12807871 [PubMed - indexed for MEDLINE]Related articlesFree article

The coactivator PGC-1 cooperates with peroxisome proliferator-activated receptor alpha in transcriptional control of nuclear genes encoding mitochondrial fatty acid oxidation enzymes.

Vega RB, Huss JM, Kelly DP.

Mol Cell Biol. 2000 Mar;20(5):1868-76.PMID: 10669761 [PubMed - indexed for MEDLINE]Related articlesFree article

Transcription coactivator PRIP, the peroxisome proliferator-activated receptor (PPAR)-interacting protein, is redundant for the function of nuclear receptors PParalpha and CAR, the constitutive androstane receptor, in mouse liver.

Sarkar J, Qi C, Guo D, Ahmed MR, Jia Y, Usuda N, Viswakarma N, Rao MS, Reddy JK.

Gene Expr. 2007;13(4-5):255-69.PMID: 17605299 [PubMed - indexed for MEDLINE]Related articles

Structural and functional consequences of mitochondrial biogenesis in human adipocytes in vitro.

Bogacka I, Ukropcova B, McNeil M, Gimble JM, Smith SR.

J Clin Endocrinol Metab. 2005 Dec;90(12):6650-6. Epub 2005 Oct 4.PMID: 16204368 [PubMed - indexed for MEDLINE]Related articlesFree article

Oxidized low density lipoprotein activates peroxisome proliferator-activated receptor-alpha (PPARalpha) and PPARgamma through MAPK-dependent COX-2 expression in macrophages.

Taketa K, Matsumura T, Yano M, Ishii N, Senokuchi T, Motoshima H, Murata Y, Kim-Mitsuyama S, Kawada T, Itabe H, Takeya M, Nishikawa T, Tsuruzoe K, Araki E.

J Biol Chem. 2008 Apr 11;283(15):9852-62. Epub 2008 Jan 21.PMID: 18208815 [PubMed - indexed for MEDLINE]Related articlesFree article

Bcl3 interacts cooperatively with peroxisome proliferator-activated receptor gamma (PPARgamma) coactivator 1alpha to coactivate nuclear receptors estrogen-related receptor alpha and PPARalpha.

Yang J, Williams RS, Kelly DP.

Mol Cell Biol. 2009 Aug;29(15):4091-102. Epub 2009 May 18.PMID: 19451226 [PubMed - indexed for MEDLINE]Related articles

Insulin-resistant heart exhibits a mitochondrial biogenic response driven by the peroxisome proliferator-activated receptor-alpha/PGC-1alpha gene regulatory pathway.

Duncan JG, Fong JL, Medeiros DM, Finck BN, Kelly DP.

Circulation. 2007 Feb 20;115(7):909-17. Epub 2007 Jan 29.PMID: 17261654 [PubMed - indexed for MEDLINE]Related articlesFree article

Hepatic PGC-1beta overexpression induces combined hyperlipidemia and modulates the response to PPARalpha activation.

Lelliott CJ, Ljungberg A, Ahnmark A, William-Olsson L, Ekroos K, Elmgren A, Arnerup G, Shoulders CC, Oscarsson J, Lindén D.

Arterioscler Thromb Vasc Biol. 2007 Dec;27(12):2707-13. Epub 2007 Oct 11.PMID: 17932310 [PubMed - indexed for MEDLINE]Related articlesFree article

Ontogenic loss of brown adipose tissue sensitivity to beta-adrenergic stimulation in the ovine.

Lomax MA, Sadiq F, Karamanlidis G, Karamitri A, Trayhurn P, Hazlerigg DG.

Endocrinology. 2007 Jan;148(1):461-8. Epub 2006 Oct 5.PMID: 17023522 [PubMed - indexed for MEDLINE]Related articlesFree article

Changes in expression levels of genes involved in fatty acid metabolism: upregulation of all three members of the PPAR family (alpha, gamma, delta) and the newly described adiponectin receptor 2, but not adiponectin receptor 1 during neonatal cardiac development of the rat.

Steinmetz M, Quentin T, Poppe A, Paul T, Jux C.

Basic Res Cardiol. 2005 May;100(3):263-9. Epub 2005 Mar 9.PMID: 15754086 [PubMed - indexed for MEDLINE]Related articles

The peroxisome proliferator-activated receptor N-terminal domain controls isotype-selective gene expression and adipogenesis.

Hummasti S, Tontonoz P.

Mol Endocrinol. 2006 Jun;20(6):1261-75. Epub 2006 Mar 23.PMID: 16556736 [PubMed - indexed for MEDLINE]Related articlesFree article

Tumor necrosis factor and interleukin 1 decrease RXRalpha, PPARalpha, PPARgamma, LXRalpha, and the coactivators SRC-1, PGC-1alpha, and PGC-1beta in liver cells.

Kim MS, Sweeney TR, Shigenaga JK, Chui LG, Moser A, Grunfeld C, Feingold KR.

Metabolism. 2007 Feb;56(2):267-79.PMID: 17224343 [PubMed - indexed for MEDLINE]Related articlesFree article

Evidence for a new human CYP1A1 regulation pathway involving PPAR-alpha and 2 PPRE sites.

Sérée E, Villard PH, Pascussi JM, Pineau T, Maurel P, Nguyen QB, Fallone F, Martin PM, Champion S, Lacarelle B, Savouret JF, Barra Y.

Gastroenterology. 2004 Nov;127(5):1436-45.PMID: 15521013 [PubMed - indexed for MEDLINE]Related articles

Human immunodeficiency virus (HIV)-1 viral protein R suppresses transcriptional activity of peroxisome proliferator-activated receptor {gamma} and inhibits adipocyte differentiation: implications for HIV-associated lipodystrophy.

Shrivastav S, Kino T, Cunningham T, Ichijo T, Schubert U, Heinklein P, Chrousos GP, Kopp JB.

Mol Endocrinol. 2008 Feb;22(2):234-47. Epub 2007 Oct 11.PMID: 17932108 [PubMed - indexed for MEDLINE]Related articlesFree article