PubMed

Mice heterozygous for tumor necrosis factor-alpha converting enzyme are protected from obesity-induced insulin resistance and diabetes.

Serino M, Menghini R, Fiorentino L, Amoruso R, Mauriello A, Lauro D, Sbraccia P, Hribal ML, Lauro R, Federici M.

Diabetes. 2007 Oct;56(10):2541-6. Epub 2007 Jul 23.PMID: 17646208 [PubMed - indexed for MEDLINE]Related articlesFree article

Tissue inhibitor of metalloproteinase 3 deficiency causes hepatic steatosis and adipose tissue inflammation in mice.

Menghini R, Menini S, Amoruso R, Fiorentino L, Casagrande V, Marzano V, Tornei F, Bertucci P, Iacobini C, Serino M, Porzio O, Hribal ML, Folli F, Khokha R, Urbani A, Lauro R, Pugliese G, Federici M.

Gastroenterology. 2009 Feb;136(2):663-72.e4. Epub 2008 Nov 6.PMID: 19027012 [PubMed - indexed for MEDLINE]Related articles

Loss-of-function mutation in myostatin reduces tumor necrosis factor alpha production and protects liver against obesity-induced insulin resistance.

Wilkes JJ, Lloyd DJ, Gekakis N.

Diabetes. 2009 May;58(5):1133-43. Epub 2009 Feb 10.PMID: 19208906 [PubMed - indexed for MEDLINE]Related articlesFree article

Chronic blockade of nitric oxide synthesis reduces adiposity and improves insulin resistance in high fat-induced obese mice.

Tsuchiya K, Sakai H, Suzuki N, Iwashima F, Yoshimoto T, Shichiri M, Hirata Y.

Endocrinology. 2007 Oct;148(10):4548-56. Epub 2007 Jun 21.PMID: 17584959 [PubMed - indexed for MEDLINE]Related articlesFree article

12-Lipoxygenase-knockout mice are resistant to inflammatory effects of obesity induced by Western diet.

Nunemaker CS, Chen M, Pei H, Kimble SD, Keller SR, Carter JD, Yang Z, Smith KM, Wu R, Bevard MH, Garmey JC, Nadler JL.

Am J Physiol Endocrinol Metab. 2008 Nov;295(5):E1065-75. Epub 2008 Sep 9.PMID: 18780776 [PubMed - indexed for MEDLINE]Related articlesFree article

Blockade of alpha4 integrin signaling ameliorates the metabolic consequences of high-fat diet-induced obesity.

Féral CC, Neels JG, Kummer C, Slepak M, Olefsky JM, Ginsberg MH.

Diabetes. 2008 Jul;57(7):1842-51. Epub 2008 Apr 21.PMID: 18426864 [PubMed - indexed for MEDLINE]Related articlesFree article

Tlr-4 deficiency selectively protects against obesity induced by diets high in saturated fat.

Davis JE, Gabler NK, Walker-Daniels J, Spurlock ME.

Obesity (Silver Spring). 2008 Jun;16(6):1248-55. Epub 2008 Apr 10.PMID: 18421279 [PubMed - indexed for MEDLINE]Related articles

Novel adipose tissue-mediated resistance to diet-induced visceral obesity in 11 beta-hydroxysteroid dehydrogenase type 1-deficient mice.

Morton NM, Paterson JM, Masuzaki H, Holmes MC, Staels B, Fievet C, Walker BR, Flier JS, Mullins JJ, Seckl JR.

Diabetes. 2004 Apr;53(4):931-8.PMID: 15047607 [PubMed - indexed for MEDLINE]Related articlesFree article

Differential expression of plasminogen activator inhibitor-1, tumor necrosis factor-alpha, TNF-alpha converting enzyme and ADAMTS family members in murine fat territories.

Voros G, Maquoi E, Collen D, Lijnen HR.

Biochim Biophys Acta. 2003 Jan 3;1625(1):36-42.PMID: 12527424 [PubMed - indexed for MEDLINE]Related articles

Effect of TNF-alpha--converting enzyme inhibitor on insulin resistance in fructose-fed rats.

Togashi N, Ura N, Higashiura K, Murakami H, Shimamoto K.

Hypertension. 2002 Feb;39(2 Pt 2):578-80.PMID: 11882611 [PubMed - indexed for MEDLINE]Related articlesFree article

Pulmonary hypoplasia in mice lacking tumor necrosis factor-alpha converting enzyme indicates an indispensable role for cell surface protein shedding during embryonic lung branching morphogenesis.

Zhao J, Chen H, Peschon JJ, Shi W, Zhang Y, Frank SJ, Warburton D.

Dev Biol. 2001 Apr 1;232(1):204-18.PMID: 11254358 [PubMed - indexed for MEDLINE]Related articles

Timp3 deficiency in insulin receptor-haploinsufficient mice promotes diabetes and vascular inflammation via increased TNF-alpha.

Federici M, Hribal ML, Menghini R, Kanno H, Marchetti V, Porzio O, Sunnarborg SW, Rizza S, Serino M, Cunsolo V, Lauro D, Mauriello A, Smookler DS, Sbraccia P, Sesti G, Lee DC, Khokha R, Accili D, Lauro R.

J Clin Invest. 2005 Dec;115(12):3494-505. Epub 2005 Nov 17.PMID: 16294222 [PubMed - indexed for MEDLINE]Related articlesFree article

Changes in adiponectin and inflammatory genes in response to hormonal imbalances in female mice and exacerbation of depot selective visceral adiposity by high-fat diet: implications for insulin resistance.

Zhang H, Chen X, Aravindakshan J, Sairam MR.

Endocrinology. 2007 Dec;148(12):5667-79. Epub 2007 Aug 23.PMID: 17717050 [PubMed - indexed for MEDLINE]Related articlesFree article

Estrogens protect against high-fat diet-induced insulin resistance and glucose intolerance in mice.

Riant E, Waget A, Cogo H, Arnal JF, Burcelin R, Gourdy P.

Endocrinology. 2009 May;150(5):2109-17. Epub 2009 Jan 22.PMID: 19164473 [PubMed - indexed for MEDLINE]Related articles

Obesity-induced inflammation in white adipose tissue is attenuated by loss of melanocortin-3 receptor signaling.

Ellacott KL, Murphy JG, Marks DL, Cone RD.

Endocrinology. 2007 Dec;148(12):6186-94. Epub 2007 Sep 27.PMID: 17901224 [PubMed - indexed for MEDLINE]Related articlesFree article

Role of PYK2 in the development of obesity and insulin resistance.

Yu Y, Ross SA, Halseth AE, Hollenbach PW, Hill RJ, Gulve EA, Bond BR.

Biochem Biophys Res Commun. 2005 Sep 9;334(4):1085-91.PMID: 16039993 [PubMed - indexed for MEDLINE]Related articles

Macrophage TNF-alpha contributes to insulin resistance and hepatic steatosis in diet-induced obesity.

De Taeye BM, Novitskaya T, McGuinness OP, Gleaves L, Medda M, Covington JW, Vaughan DE.

Am J Physiol Endocrinol Metab. 2007 Sep;293(3):E713-25. Epub 2007 Jun 19.PMID: 17578885 [PubMed - indexed for MEDLINE]Related articlesFree article

Receptors for tumor necrosis factor-alpha play a protective role against obesity and alter adipose tissue macrophage status.

Pamir N, McMillen TS, Kaiyala KJ, Schwartz MW, LeBoeuf RC.

Endocrinology. 2009 Sep;150(9):4124-34. Epub 2009 May 28.PMID: 19477937 [PubMed - indexed for MEDLINE]Related articles

C3H/HeJ mice carrying a toll-like receptor 4 mutation are protected against the development of insulin resistance in white adipose tissue in response to a high-fat diet.

Poggi M, Bastelica D, Gual P, Iglesias MA, Gremeaux T, Knauf C, Peiretti F, Verdier M, Juhan-Vague I, Tanti JF, Burcelin R, Alessi MC.

Diabetologia. 2007 Jun;50(6):1267-76. Epub 2007 Apr 11.PMID: 17426960 [PubMed - indexed for MEDLINE]Related articles

Protection from obesity-induced insulin resistance in mice lacking TNF-alpha function.

Uysal KT, Wiesbrock SM, Marino MW, Hotamisligil GS.

Nature. 1997 Oct 9;389(6651):610-4.PMID: 9335502 [PubMed - indexed for MEDLINE]Related articles