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    Results: 1 to 20 of 277

    1.

    Interaction between Munc13-1 and RIM is critical for glucagon-like peptide-1 mediated rescue of exocytotic defects in Munc13-1 deficient pancreatic beta-cells.

    Kwan EP, Xie L, Sheu L, Ohtsuka T, Gaisano HY.

    Diabetes. 2007 Oct;56(10):2579-88. Epub 2007 Jul 16.PMID: 17639022 [PubMed - indexed for MEDLINE]Related articlesFree article

    2.

    Activation of exchange protein directly activated by cyclic adenosine monophosphate and protein kinase A regulate common and distinct steps in promoting plasma membrane exocytic and granule-to-granule fusions in rat islet beta cells.

    Kwan EP, Gao X, Leung YM, Gaisano HY.

    Pancreas. 2007 Oct;35(3):e45-54.PMID: 17895835 [PubMed - indexed for MEDLINE]Related articles

    3.

    Kinetics of Rab27a-dependent actions on vesicle docking and priming in pancreatic beta-cells.

    Merrins MJ, Stuenkel EL.

    J Physiol. 2008 Nov 15;586(Pt 22):5367-81. Epub 2008 Sep 18.PMID: 18801842 [PubMed - indexed for MEDLINE]Related articlesFree article

    4.

    Critical role of cAMP-GEFII--Rim2 complex in incretin-potentiated insulin secretion.

    Kashima Y, Miki T, Shibasaki T, Ozaki N, Miyazaki M, Yano H, Seino S.

    J Biol Chem. 2001 Dec 7;276(49):46046-53. Epub 2001 Oct 11.PMID: 11598134 [PubMed - indexed for MEDLINE]Related articlesFree article

    5.

    SUR1 regulates PKA-independent cAMP-induced granule priming in mouse pancreatic B-cells.

    Eliasson L, Ma X, Renström E, Barg S, Berggren PO, Galvanovskis J, Gromada J, Jing X, Lundquist I, Salehi A, Sewing S, Rorsman P.

    J Gen Physiol. 2003 Mar;121(3):181-97.PMID: 12601083 [PubMed - indexed for MEDLINE]Related articlesFree article

    6.

    Munc13-1 deficiency reduces insulin secretion and causes abnormal glucose tolerance.

    Kwan EP, Xie L, Sheu L, Nolan CJ, Prentki M, Betz A, Brose N, Gaisano HY.

    Diabetes. 2006 May;55(5):1421-9.PMID: 16644700 [PubMed - indexed for MEDLINE]Related articlesFree article

    7.

    Truncation of SNAP-25 reduces the stimulatory action of cAMP on rapid exocytosis in insulin-secreting cells.

    Vikman J, Svensson H, Huang YC, Kang Y, Andersson SA, Gaisano HY, Eliasson L.

    Am J Physiol Endocrinol Metab. 2009 Aug;297(2):E452-61. Epub 2009 Jun 9.PMID: 19509185 [PubMed - indexed for MEDLINE]Related articles

    8.

    Glucagon stimulates exocytosis in mouse and rat pancreatic alpha-cells by binding to glucagon receptors.

    Ma X, Zhang Y, Gromada J, Sewing S, Berggren PO, Buschard K, Salehi A, Vikman J, Rorsman P, Eliasson L.

    Mol Endocrinol. 2005 Jan;19(1):198-212. Epub 2004 Sep 30.PMID: 15459251 [PubMed - indexed for MEDLINE]Related articlesFree article

    9.

    Regulation of insulin exocytosis by Munc13-1.

    Sheu L, Pasyk EA, Ji J, Huang X, Gao X, Varoqueaux F, Brose N, Gaisano HY.

    J Biol Chem. 2003 Jul 25;278(30):27556-63. Epub 2003 May 13.PMID: 12871971 [PubMed - indexed for MEDLINE]Related articlesFree article

    10.

    cAMP sensor Epac as a determinant of ATP-sensitive potassium channel activity in human pancreatic beta cells and rat INS-1 cells.

    Kang G, Chepurny OG, Malester B, Rindler MJ, Rehmann H, Bos JL, Schwede F, Coetzee WA, Holz GG.

    J Physiol. 2006 Jun 15;573(Pt 3):595-609. Epub 2006 Apr 13.PMID: 16613879 [PubMed - indexed for MEDLINE]Related articlesFree article

    11.

    Epac-selective cAMP analog 8-pCPT-2'-O-Me-cAMP as a stimulus for Ca2+-induced Ca2+ release and exocytosis in pancreatic beta-cells.

    Kang G, Joseph JW, Chepurny OG, Monaco M, Wheeler MB, Bos JL, Schwede F, Genieser HG, Holz GG.

    J Biol Chem. 2003 Mar 7;278(10):8279-85. Epub 2002 Dec 20.PMID: 12496249 [PubMed - indexed for MEDLINE]Related articlesFree article

    12.

    Epac: A new cAMP-binding protein in support of glucagon-like peptide-1 receptor-mediated signal transduction in the pancreatic beta-cell.

    Holz GG.

    Diabetes. 2004 Jan;53(1):5-13. Review.PMID: 14693691 [PubMed - indexed for MEDLINE]Related articlesFree article

    13.

    Munc13-1 is required for the sustained release of insulin from pancreatic beta cells.

    Kang L, He Z, Xu P, Fan J, Betz A, Brose N, Xu T.

    Cell Metab. 2006 Jun;3(6):463-8. Epub 2006 May 11.PMID: 16697276 [PubMed - indexed for MEDLINE]Related articles

    14.

    Two cAMP-dependent pathways differentially regulate exocytosis of large dense-core and small vesicles in mouse beta-cells.

    Hatakeyama H, Takahashi N, Kishimoto T, Nemoto T, Kasai H.

    J Physiol. 2007 Aug 1;582(Pt 3):1087-98. Epub 2007 May 17.PMID: 17510178 [PubMed - indexed for MEDLINE]Related articlesFree article

    15.

    Interaction of ATP sensor, cAMP sensor, Ca2+ sensor, and voltage-dependent Ca2+ channel in insulin granule exocytosis.

    Shibasaki T, Sunaga Y, Fujimoto K, Kashima Y, Seino S.

    J Biol Chem. 2004 Feb 27;279(9):7956-61. Epub 2003 Dec 3.PMID: 14660679 [PubMed - indexed for MEDLINE]Related articlesFree article

    16.

    Piccolo, a Ca2+ sensor in pancreatic beta-cells. Involvement of cAMP-GEFII.Rim2. Piccolo complex in cAMP-dependent exocytosis.

    Fujimoto K, Shibasaki T, Yokoi N, Kashima Y, Matsumoto M, Sasaki T, Tajima N, Iwanaga T, Seino S.

    J Biol Chem. 2002 Dec 27;277(52):50497-502. Epub 2002 Oct 24.PMID: 12401793 [PubMed - indexed for MEDLINE]Related articlesFree article

    17.

    Differential modulation of Cav1.2 and Cav1.3-mediated glucose-stimulated insulin secretion by cAMP in INS-1 cells: distinct roles for exchange protein directly activated by cAMP 2 (Epac2) and protein kinase A.

    Liu G, Jacobo SM, Hilliard N, Hockerman GH.

    J Pharmacol Exp Ther. 2006 Jul;318(1):152-60. Epub 2006 Mar 24.PMID: 16565168 [PubMed - indexed for MEDLINE]Related articlesFree article

    18.

    Triphenyltin impairs a protein kinase A (PKA)-dependent increase of cytosolic Na+ and Ca2+ and PKA-independent increase of cytosolic Ca2+ associated with insulin secretion in hamster pancreatic beta-cells.

    Miura Y, Matsui H.

    Toxicol Appl Pharmacol. 2006 Nov 1;216(3):363-72. Epub 2006 Jun 6.PMID: 16837018 [PubMed - indexed for MEDLINE]Related articles

    19.

    cAMP-activated protein kinase-independent potentiation of insulin secretion by cAMP is impaired in SUR1 null islets.

    Nakazaki M, Crane A, Hu M, Seghers V, Ullrich S, Aguilar-Bryan L, Bryan J.

    Diabetes. 2002 Dec;51(12):3440-9.PMID: 12453898 [PubMed - indexed for MEDLINE]Related articlesFree article

    20.

    Cyclic AMP/cAMP-GEF pathway amplifies insulin exocytosis induced by Ca2+ and ATP in rat islet beta-cells.

    Hashiguchi H, Nakazaki M, Koriyama N, Fukudome M, Aso K, Tei C.

    Diabetes Metab Res Rev. 2006 Jan-Feb;22(1):64-71.PMID: 16028217 [PubMed - indexed for MEDLINE]Related articles

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