PubMed

PTEN expression contributes to the regulation of muscle protein degradation in diabetes.

Hu Z, Lee IH, Wang X, Sheng H, Zhang L, Du J, Mitch WE.

Diabetes. 2007 Oct;56(10):2449-56. Epub 2007 Jul 10.PMID: 17623817 [PubMed - indexed for MEDLINE]Related articlesFree article

Genetic analysis of the role of the PI3K-Akt pathway in lipopolysaccharide-induced cytokine and tissue factor gene expression in monocytes/macrophages.

Luyendyk JP, Schabbauer GA, Tencati M, Holscher T, Pawlinski R, Mackman N.

J Immunol. 2008 Mar 15;180(6):4218-26.PMID: 18322234 [PubMed - indexed for MEDLINE]Related articlesFree article

Insulin resistance accelerates muscle protein degradation: Activation of the ubiquitin-proteasome pathway by defects in muscle cell signaling.

Wang X, Hu Z, Hu J, Du J, Mitch WE.

Endocrinology. 2006 Sep;147(9):4160-8. Epub 2006 Jun 15.PMID: 16777975 [PubMed - indexed for MEDLINE]Related articlesFree article

IGF-I stimulates muscle growth by suppressing protein breakdown and expression of atrophy-related ubiquitin ligases, atrogin-1 and MuRF1.

Sacheck JM, Ohtsuka A, McLary SC, Goldberg AL.

Am J Physiol Endocrinol Metab. 2004 Oct;287(4):E591-601. Epub 2004 Apr 20.PMID: 15100091 [PubMed - indexed for MEDLINE]Related articlesFree article

Regulation of muscle protein degradation: coordinated control of apoptotic and ubiquitin-proteasome systems by phosphatidylinositol 3 kinase.

Lee SW, Dai G, Hu Z, Wang X, Du J, Mitch WE.

J Am Soc Nephrol. 2004 Jun;15(6):1537-45.PMID: 15153564 [PubMed - indexed for MEDLINE]Related articlesFree article

Pancreas-specific Pten deficiency causes partial resistance to diabetes and elevated hepatic AKT signaling.

Tong Z, Fan Y, Zhang W, Xu J, Cheng J, Ding M, Deng H.

Cell Res. 2009 Jun;19(6):710-9.PMID: 19365404 [PubMed - indexed for MEDLINE]Related articles

Pten (phosphatase and tensin homologue gene) haploinsufficiency promotes insulin hypersensitivity.

Wong JT, Kim PT, Peacock JW, Yau TY, Mui AL, Chung SW, Sossi V, Doudet D, Green D, Ruth TJ, Parsons R, Verchere CB, Ong CJ.

Diabetologia. 2007 Feb;50(2):395-403. Epub 2006 Dec 29.PMID: 17195063 [PubMed - indexed for MEDLINE]Related articlesFree article

Reactive nitrogen species induced by hyperglycemia suppresses Akt signaling and triggers apoptosis by upregulating phosphatase PTEN (phosphatase and tensin homologue deleted on chromosome 10) in an LKB1-dependent manner.

Song P, Wu Y, Xu J, Xie Z, Dong Y, Zhang M, Zou MH.

Circulation. 2007 Oct 2;116(14):1585-95. Epub 2007 Sep 17.PMID: 17875968 [PubMed - indexed for MEDLINE]Related articlesFree article

Na+/H+ exchanger regulatory factor 1 inhibits platelet-derived growth factor signaling in breast cancer cells.

Pan Y, Weinman EJ, Dai JL.

Breast Cancer Res. 2008;10(1):R5. Epub 2008 Jan 11.PMID: 18190691 [PubMed - indexed for MEDLINE]Related articlesFree article

Cardiac muscle protein catabolism in diabetes mellitus: activation of the ubiquitin-proteasome system by insulin deficiency.

Hu J, Klein JD, Du J, Wang XH.

Endocrinology. 2008 Nov;149(11):5384-90. Epub 2008 Jul 24.PMID: 18653708 [PubMed - indexed for MEDLINE]Related articlesFree article

Targeted deletion of PTEN in smooth muscle cells results in vascular remodeling and recruitment of progenitor cells through induction of stromal cell-derived factor-1alpha.

Nemenoff RA, Simpson PA, Furgeson SB, Kaplan-Albuquerque N, Crossno J, Garl PJ, Cooper J, Weiser-Evans MC.

Circ Res. 2008 May 9;102(9):1036-45. Epub 2008 Mar 13.PMID: 18340011 [PubMed - indexed for MEDLINE]Related articlesFree article

Phosphatase and tensin homolog deleted on chromosome 10 suppression is an important process in peroxisome proliferator-activated receptor-gamma signaling in adipocytes and myotubes.

Kim KY, Cho HS, Jung WH, Kim SS, Cheon HG.

Mol Pharmacol. 2007 Jun;71(6):1554-62. Epub 2007 Mar 2.PMID: 17337625 [PubMed - indexed for MEDLINE]Related articlesFree article

Inactivation of Pten in osteo-chondroprogenitor cells leads to epiphyseal growth plate abnormalities and skeletal overgrowth.

Ford-Hutchinson AF, Ali Z, Lines SE, Hallgrímsson B, Boyd SK, Jirik FR.

J Bone Miner Res. 2007 Aug;22(8):1245-59.PMID: 17456009 [PubMed - indexed for MEDLINE]Related articles

Phosphatase and tensin homolog regulation of islet growth and glucose homeostasis.

Kushner JA, Simpson L, Wartschow LM, Guo S, Rankin MM, Parsons R, White MF.

J Biol Chem. 2005 Nov 25;280(47):39388-93. Epub 2005 Sep 16.PMID: 16170201 [PubMed - indexed for MEDLINE]Related articlesFree article

Muscle-specific Pten deletion protects against insulin resistance and diabetes.

Wijesekara N, Konrad D, Eweida M, Jefferies C, Liadis N, Giacca A, Crackower M, Suzuki A, Mak TW, Kahn CR, Klip A, Woo M.

Mol Cell Biol. 2005 Feb;25(3):1135-45.PMID: 15657439 [PubMed - indexed for MEDLINE]Related articlesFree article

Phosphorylation of the survival kinase Akt by superoxide is dependent on an ascorbate-reversible oxidation of PTEN.

Lim S, Clément MV.

Free Radic Biol Med. 2007 Apr 15;42(8):1178-92. Epub 2007 Jan 12.PMID: 17382199 [PubMed - indexed for MEDLINE]Related articles

Absence of caspase-3 protects against denervation-induced skeletal muscle atrophy.

Plant PJ, Bain JR, Correa JE, Woo M, Batt J.

J Appl Physiol. 2009 Jul;107(1):224-34. Epub 2009 Apr 23.PMID: 19390003 [PubMed - indexed for MEDLINE]Related articles

Essential role of Pten in body size determination and pancreatic beta-cell homeostasis in vivo.

Nguyen KT, Tajmir P, Lin CH, Liadis N, Zhu XD, Eweida M, Tolasa-Karaman G, Cai F, Wang R, Kitamura T, Belsham DD, Wheeler MB, Suzuki A, Mak TW, Woo M.

Mol Cell Biol. 2006 Jun;26(12):4511-8.PMID: 16738317 [PubMed - indexed for MEDLINE]Related articlesFree article

[PTEN/PI3K pathways are involved in the signal transduction of myocardial remodeling in patients with congestive heart failure]

Yang YJ, Zhu WL, Zhang X, Zhou XW, Zhu ZM.

Zhonghua Yi Xue Za Zhi. 2005 May 11;85(17):1201-4. Chinese. PMID: 16029597 [PubMed - indexed for MEDLINE]Related articles

Modulation by insulin-like growth factor I of the phosphatase PTEN in astrocytes.

Fernández S, García-García M, Torres-Alemán I.

Biochim Biophys Acta. 2008 May;1783(5):803-12. Epub 2007 Nov 13.PMID: 18062928 [PubMed - indexed for MEDLINE]Related articles