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Loss-of-function genetic diseases and the concept of pharmaceutical targets.

Ségalat L.

Orphanet J Rare Dis. 2007 Jul 2;2:30.PMID: 17605800 [PubMed - indexed for MEDLINE]Related articlesFree article

Loss-of-function genetic diseases and the concept of pharmaceutical targets.

Ségalat L.

Orphanet J Rare Dis. 2007;2:30. Review.PMID: 17674486 [PubMed - indexed for MEDLINE]Related articlesFree article

Targetability of human disease genes.

Sakharkar MK, Sakharkar KR.

Curr Drug Discov Technol. 2007 Jun;4(1):48-58. Review.PMID: 17630928 [PubMed - indexed for MEDLINE]Related articles

Genetics in drug discovery and development: challenge and promise of individualizing treatment in common complex diseases.

Lindpaintner K.

Br Med Bull. 1999;55(2):471-91. Review. No abstract available. PMID: 10723870 [PubMed - indexed for MEDLINE]Related articlesFree article

Pharmacogenomics and the drug discovery pipeline: when should it be implemented?

Penny MA, McHale D.

Am J Pharmacogenomics. 2005;5(1):53-62. Review.PMID: 15727489 [PubMed - indexed for MEDLINE]Related articles

Human monogenic disorders - a source of novel drug targets.

Brinkman RR, Dubé MP, Rouleau GA, Orr AC, Samuels ME.

Nat Rev Genet. 2006 Apr;7(4):249-60. Review.PMID: 16534513 [PubMed - indexed for MEDLINE]Related articles

The identification and validation of common disease genes: relevance to the drug development process.

Holmberg M, Lejon K.

Curr Opin Mol Ther. 2001 Dec;3(6):533-7. Review.PMID: 11804267 [PubMed - indexed for MEDLINE]Related articles

The increasing importance of genetic variation in drug discovery and development.

Labaudinière R.

Curr Opin Mol Ther. 2002 Dec;4(6):559-64. Review.PMID: 12596357 [PubMed - indexed for MEDLINE]Related articles

Pharmacogenetics.

Vesell ES.

Biochem Pharmacol. 1975 Feb 15;24(4):445-50. No abstract available. PMID: 1167457 [PubMed - indexed for MEDLINE]Related articles

Overview of pharmacogenetics.

Katz DA, Bhathena A.

Curr Protoc Hum Genet. 2009 Jan;Chapter 9:Unit 9.19. Review.PMID: 19170034 [PubMed - indexed for MEDLINE]Related articles

Richard Weinshilboum: Pharmacogenetics: The future is here!

Weinshilboum R.

Mol Interv. 2003 May;3(3):118-22.PMID: 14993417 [PubMed - indexed for MEDLINE]Related articlesFree article

Developmental and pediatric pharmacogenomics.

Leeder JS.

Pharmacogenomics. 2003 May;4(3):331-41. Review.PMID: 12718723 [PubMed - indexed for MEDLINE]Related articles

Novel methods for detecting epistasis in pharmacogenomics studies.

Motsinger AA, Ritchie MD, Reif DM.

Pharmacogenomics. 2007 Sep;8(9):1229-41. Review.PMID: 17924838 [PubMed - indexed for MEDLINE]Related articles

Aminoglycoside-induced translational read-through in disease: overcoming nonsense mutations by pharmacogenetic therapy.

Zingman LV, Park S, Olson TM, Alekseev AE, Terzic A.

Clin Pharmacol Ther. 2007 Jan;81(1):99-103. Review.PMID: 17186006 [PubMed - indexed for MEDLINE]Related articles

Systems approaches for pharmacogenetics and pharmacogenomics.

Bader JS.

Pharmacogenomics. 2008 Mar;9(3):257-62. No abstract available. PMID: 18303961 [PubMed - indexed for MEDLINE]Related articlesFree article

Connecting chemosensitivity, gene expression and disease.

Covell DG.

Trends Pharmacol Sci. 2008 Jan;29(1):1-5. Epub 2007 Dec 4.PMID: 18055024 [PubMed - indexed for MEDLINE]Related articles

Protein misfolding disorders and rational design of antimisfolding agents.

Estrada LD, Yowtak J, Soto C.

Methods Mol Biol. 2006;340:277-93. Review.PMID: 16957342 [PubMed - indexed for MEDLINE]Related articles

Human genetic variation and personalized medicine.

Agrawal S, Khan F.

Indian J Physiol Pharmacol. 2007 Jan-Mar;51(1):7-28. Review.PMID: 17877289 [PubMed - indexed for MEDLINE]Related articles

[Pharmacogenetics: forerunner for individualized medicine]

Lindpaintner K.

Ther Umsch. 2003 Aug;60(8):487-92. German. No abstract available. PMID: 14502858 [PubMed - indexed for MEDLINE]Related articles

Redesign of aminoglycosides for treatment of human genetic diseases caused by premature stop mutations.

Nudelman I, Rebibo-Sabbah A, Shallom-Shezifi D, Hainrichson M, Stahl I, Ben-Yosef T, Baasov T.

Bioorg Med Chem Lett. 2006 Dec 15;16(24):6310-5. Epub 2006 Sep 25.PMID: 16997553 [PubMed - indexed for MEDLINE]Related articles