PubMed

Deficiency of Cbl-b gene enhances infiltration and activation of macrophages in adipose tissue and causes peripheral insulin resistance in mice.

Hirasaka K, Kohno S, Goto J, Furochi H, Mawatari K, Harada N, Hosaka T, Nakaya Y, Ishidoh K, Obata T, Ebina Y, Gu H, Takeda S, Kishi K, Nikawa T.

Diabetes. 2007 Oct;56(10):2511-22. Epub 2007 Jun 29.PMID: 17601987 [PubMed - indexed for MEDLINE]Related articlesFree article

The farnesoid X receptor modulates adiposity and peripheral insulin sensitivity in mice.

Cariou B, van Harmelen K, Duran-Sandoval D, van Dijk TH, Grefhorst A, Abdelkarim M, Caron S, Torpier G, Fruchart JC, Gonzalez FJ, Kuipers F, Staels B.

J Biol Chem. 2006 Apr 21;281(16):11039-49. Epub 2006 Jan 30.PMID: 16446356 [PubMed - indexed for MEDLINE]Related articlesFree article

Macrophages block insulin action in adipocytes by altering expression of signaling and glucose transport proteins.

Lumeng CN, Deyoung SM, Saltiel AR.

Am J Physiol Endocrinol Metab. 2007 Jan;292(1):E166-74. Epub 2006 Aug 22.PMID: 16926380 [PubMed - indexed for MEDLINE]Related articlesFree article

Chronic ethanol-induced insulin resistance is associated with macrophage infiltration into adipose tissue and altered expression of adipocytokines.

Kang L, Sebastian BM, Pritchard MT, Pratt BT, Previs SF, Nagy LE.

Alcohol Clin Exp Res. 2007 Sep;31(9):1581-8. Epub 2007 Jul 11.PMID: 17624994 [PubMed - indexed for MEDLINE]Related articles

Differential role of SH2-B and APS in regulating energy and glucose homeostasis.

Li M, Ren D, Iseki M, Takaki S, Rui L.

Endocrinology. 2006 May;147(5):2163-70. Epub 2006 Feb 2.PMID: 16455776 [PubMed - indexed for MEDLINE]Related articlesFree article

c-Cbl-deficient mice have reduced adiposity, higher energy expenditure, and improved peripheral insulin action.

Molero JC, Jensen TE, Withers PC, Couzens M, Herzog H, Thien CB, Langdon WY, Walder K, Murphy MA, Bowtell DD, James DE, Cooney GJ.

J Clin Invest. 2004 Nov;114(9):1326-33.PMID: 15520865 [PubMed - indexed for MEDLINE]Related articlesFree article

Overexpression of monocyte chemoattractant protein-1 in adipose tissues causes macrophage recruitment and insulin resistance.

Kamei N, Tobe K, Suzuki R, Ohsugi M, Watanabe T, Kubota N, Ohtsuka-Kowatari N, Kumagai K, Sakamoto K, Kobayashi M, Yamauchi T, Ueki K, Oishi Y, Nishimura S, Manabe I, Hashimoto H, Ohnishi Y, Ogata H, Tokuyama K, Tsunoda M, Ide T, Murakami K, Nagai R, Kadowaki T.

J Biol Chem. 2006 Sep 8;281(36):26602-14. Epub 2006 Jun 29.PMID: 16809344 [PubMed - indexed for MEDLINE]Related articlesFree article

Oxidative stress induces insulin resistance by activating the nuclear factor-kappa B pathway and disrupting normal subcellular distribution of phosphatidylinositol 3-kinase.

Ogihara T, Asano T, Katagiri H, Sakoda H, Anai M, Shojima N, Ono H, Fujishiro M, Kushiyama A, Fukushima Y, Kikuchi M, Noguchi N, Aburatani H, Gotoh Y, Komuro I, Fujita T.

Diabetologia. 2004 May;47(5):794-805. Epub 2004 May 1.PMID: 15127200 [PubMed - indexed for MEDLINE]Related articles

Genetic ablation of the c-Cbl ubiquitin ligase domain results in increased energy expenditure and improved insulin action.

Molero JC, Turner N, Thien CB, Langdon WY, James DE, Cooney GJ.

Diabetes. 2006 Dec;55(12):3411-7.PMID: 17130487 [PubMed - indexed for MEDLINE]Related articlesFree article

GLUT4 glucose transporter deficiency increases hepatic lipid production and peripheral lipid utilization.

Kotani K, Peroni OD, Minokoshi Y, Boss O, Kahn BB.

J Clin Invest. 2004 Dec;114(11):1666-75.PMID: 15578099 [PubMed - indexed for MEDLINE]Related articlesFree article

Adipocyte/macrophage fatty acid-binding proteins contribute to metabolic deterioration through actions in both macrophages and adipocytes in mice.

Furuhashi M, Fucho R, Görgün CZ, Tuncman G, Cao H, Hotamisligil GS.

J Clin Invest. 2008 Jul;118(7):2640-50.PMID: 18551191 [PubMed - indexed for MEDLINE]Related articlesFree article

Macrophage-specific PPARgamma controls alternative activation and improves insulin resistance.

Odegaard JI, Ricardo-Gonzalez RR, Goforth MH, Morel CR, Subramanian V, Mukundan L, Red Eagle A, Vats D, Brombacher F, Ferrante AW, Chawla A.

Nature. 2007 Jun 28;447(7148):1116-20. Epub 2007 May 21.PMID: 17515919 [PubMed - indexed for MEDLINE]Related articlesFree article

Obesity-related upregulation of monocyte chemotactic factors in adipocytes: involvement of nuclear factor-kappaB and c-Jun NH2-terminal kinase pathways.

Jiao P, Chen Q, Shah S, Du J, Tao B, Tzameli I, Yan W, Xu H.

Diabetes. 2009 Jan;58(1):104-15. Epub 2008 Oct 3.PMID: 18835938 [PubMed - indexed for MEDLINE]Related articlesFree article

MCP-1 contributes to macrophage infiltration into adipose tissue, insulin resistance, and hepatic steatosis in obesity.

Kanda H, Tateya S, Tamori Y, Kotani K, Hiasa K, Kitazawa R, Kitazawa S, Miyachi H, Maeda S, Egashira K, Kasuga M.

J Clin Invest. 2006 Jun;116(6):1494-505. Epub 2006 May 11.PMID: 16691291 [PubMed - indexed for MEDLINE]Related articlesFree article

Mas deficiency in FVB/N mice produces marked changes in lipid and glycemic metabolism.

Santos SH, Fernandes LR, Mario EG, Ferreira AV, Pôrto LC, Alvarez-Leite JI, Botion LM, Bader M, Alenina N, Santos RA.

Diabetes. 2008 Feb;57(2):340-7. Epub 2007 Nov 19.PMID: 18025412 [PubMed - indexed for MEDLINE]Related articlesFree article

The C3a anaphylatoxin receptor is a key mediator of insulin resistance and functions by modulating adipose tissue macrophage infiltration and activation.

Mamane Y, Chung Chan C, Lavallee G, Morin N, Xu LJ, Huang J, Gordon R, Thomas W, Lamb J, Schadt EE, Kennedy BP, Mancini JA.

Diabetes. 2009 Sep;58(9):2006-17. Epub 2009 Jul 6.PMID: 19581423 [PubMed - indexed for MEDLINE]Related articlesFree article

Cellular and molecular mechanisms of adipose tissue plasticity in muscle insulin receptor knockout mice.

Cariou B, Postic C, Boudou P, Burcelin R, Kahn CR, Girard J, Burnol AF, Mauvais-Jarvis F.

Endocrinology. 2004 Apr;145(4):1926-32. Epub 2003 Dec 18.PMID: 14684612 [PubMed - indexed for MEDLINE]Related articlesFree article

The role of GM-CSF in adipose tissue inflammation.

Kim DH, Sandoval D, Reed JA, Matter EK, Tolod EG, Woods SC, Seeley RJ.

Am J Physiol Endocrinol Metab. 2008 Nov;295(5):E1038-46. Epub 2008 Sep 2.PMID: 18765677 [PubMed - indexed for MEDLINE]Related articlesFree article

APS facilitates c-Cbl tyrosine phosphorylation and GLUT4 translocation in response to insulin in 3T3-L1 adipocytes.

Liu J, Kimura A, Baumann CA, Saltiel AR.

Mol Cell Biol. 2002 Jun;22(11):3599-609.PMID: 11997497 [PubMed - indexed for MEDLINE]Related articlesFree article

Recent advances in the relationship between obesity, inflammation, and insulin resistance.

Bastard JP, Maachi M, Lagathu C, Kim MJ, Caron M, Vidal H, Capeau J, Feve B.

Eur Cytokine Netw. 2006 Mar;17(1):4-12. Review.PMID: 16613757 [PubMed - indexed for MEDLINE]Related articles