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Bone marrow is a preferential homing site for autoreactive T-cells in type 1 diabetes.
Li R, Perez N, Karumuthil-Melethil S, Vasu C.
Diabetes. 2007 Sep;56(9):2251-9. Epub 2007 Jun 27.PMID: 17596402 [PubMed - indexed for MEDLINE]Related articlesFree article
Diabetogenic T cells are primed both in pancreatic and gut-associated lymph nodes in NOD mice.
Jaakkola I, Jalkanen S, Hänninen A.
Eur J Immunol. 2003 Dec;33(12):3255-64.PMID: 14635033 [PubMed - indexed for MEDLINE]Related articles
Beta-cell apoptosis in an accelerated model of autoimmune diabetes.
Augstein P, Stephens LA, Allison J, Elefanty AG, Ekberg M, Kay TW, Harrison LC.
Mol Med. 1998 Aug;4(8):495-501.PMID: 9742505 [PubMed - indexed for MEDLINE]Related articlesFree article
A Reg family protein is overexpressed in islets from a patient with new-onset type 1 diabetes and acts as T-cell autoantigen in NOD mice.
Gurr W, Yavari R, Wen L, Shaw M, Mora C, Christa L, Sherwin RS.
Diabetes. 2002 Feb;51(2):339-46.PMID: 11812740 [PubMed - indexed for MEDLINE]Related articlesFree article
Homing of lymphocytes into islets of Langerhans in prediabetic non-obese diabetic mice is not restricted to autoreactive T cells.
Faveeuw C, Gagnerault MC, Kraal G, Lepault F.
Int Immunol. 1995 Dec;7(12):1905-13.PMID: 8746560 [PubMed - indexed for MEDLINE]Related articles
Role of L-selectin in the development of autoimmune diabetes in non-obese diabetic mice.
Mora C, Grewal IS, Wong FS, Flavell RA.
Int Immunol. 2004 Feb;16(2):257-64.PMID: 14734611 [PubMed - indexed for MEDLINE]Related articlesFree article
Marginal-zone B-cells of nonobese diabetic mice expand with diabetes onset, invade the pancreatic lymph nodes, and present autoantigen to diabetogenic T-cells.
Mariño E, Batten M, Groom J, Walters S, Liuwantara D, Mackay F, Grey ST.
Diabetes. 2008 Feb;57(2):395-404. Epub 2007 Nov 19.PMID: 18025414 [PubMed - indexed for MEDLINE]Related articlesFree article
Protection against autoimmune diabetes with oral insulin is associated with the presence of IL-4 type 2 T-cells in the pancreas and pancreatic lymph nodes.
Ploix C, Bergerot I, Fabien N, Perche S, Moulin V, Thivolet C.
Diabetes. 1998 Jan;47(1):39-44.PMID: 9421372 [PubMed - indexed for MEDLINE]Related articles
A self MHC class II beta-chain peptide prevents diabetes in nonobese diabetic mice.
Chaturvedi P, Agrawal B, Zechel M, Lee-Chan E, Singh B.
J Immunol. 2000 Jun 15;164(12):6610-20.PMID: 10843721 [PubMed - indexed for MEDLINE]Related articlesFree article
Lymphoid hyperplasia, CD45RBhigh to CD45RBlow T-cell imbalance, and suppression of Type I diabetes mellitus result from TNF blockade in NOD-->NOD-scid adoptive T cell transfer.
Brown GR, Silva MD, Thompson PA, Beutler B.
Diabetologia. 1998 Dec;41(12):1502-10.PMID: 9867218 [PubMed - indexed for MEDLINE]Related articles
NOD fetal thymus organ culture: an in vitro model for the development of T cells involved in IDDM.
Wilson SS, DeLuca D.
J Autoimmun. 1997 Oct;10(5):461-72.PMID: 9376074 [PubMed - indexed for MEDLINE]Related articles
Different diabetogenic potential of autoaggressive CD8+ clones associated with IFN-gamma-inducible protein 10 (CXC chemokine ligand 10) production but not cytokine expression, cytolytic activity, or homing characteristics.
Ejrnaes M, Videbaek N, Christen U, Cooke A, Michelsen BK, von Herrath M.
J Immunol. 2005 Mar 1;174(5):2746-55.PMID: 15728483 [PubMed - indexed for MEDLINE]Related articlesFree article
Lymphocyte function associated antigen-1, integrin alpha 4, and L-selectin mediate T-cell homing to the pancreas in the model of adoptive transfer of diabetes in NOD mice.
Fabien N, Bergerot I, Orgiazzi J, Thivolet C.
Diabetes. 1996 Sep;45(9):1181-6.PMID: 8772719 [PubMed - indexed for MEDLINE]Related articles
Human chorionic gonadotropin is an immune modulator and can prevent autoimmune diabetes in NOD mice.
Khil LY, Jun HS, Kwon H, Yoo JK, Kim S, Notkins AL, Yoon JW.
Diabetologia. 2007 Oct;50(10):2147-55. Epub 2007 Aug 4.PMID: 17676307 [PubMed - indexed for MEDLINE]Related articles
Autoreactive diabetogenic T-cells in NOD mice can efficiently expand from a greatly reduced precursor pool.
Serreze DV, Johnson EA, Chapman HD, Graser RT, Marron MP, DiLorenzo TP, Silveira P, Yoshimura Y, Nathenson SG, Joyce S.
Diabetes. 2001 Sep;50(9):1992-2000.PMID: 11522664 [PubMed - indexed for MEDLINE]Related articlesFree article
The target cell response to cytokines governs the autoreactive T cell repertoire in the pancreas of NOD mice.
Hultcrantz M, Jacobson S, Hill NJ, Santamaria P, Flodström-Tullberg M.
Diabetologia. 2009 Feb;52(2):299-305. Epub 2008 Nov 25.PMID: 19031069 [PubMed - indexed for MEDLINE]Related articles
Homing of human autoreactive T cells into pancreatic tissue of NOD-scid mice.
van Halteren AG, Kardol MJ, Mulder A, Roep BO.
Diabetologia. 2005 Jan;48(1):75-82. Epub 2004 Dec 24.PMID: 15619074 [PubMed - indexed for MEDLINE]Related articles
Activating Fc gamma receptors participate in the development of autoimmune diabetes in NOD mice.
Inoue Y, Kaifu T, Sugahara-Tobinai A, Nakamura A, Miyazaki J, Takai T.
J Immunol. 2007 Jul 15;179(2):764-74.PMID: 17617565 [PubMed - indexed for MEDLINE]Related articlesFree article
Regulation of autoimmune diabetes by interleukin 3-dependent bone marrow-derived cells in NOD mice.
Ito A, Aoyanagi N, Maki T.
J Autoimmun. 1997 Aug;10(4):331-8.PMID: 9237796 [PubMed - indexed for MEDLINE]Related articles
Functional waning of naturally occurring CD4+ regulatory T-cells contributes to the onset of autoimmune diabetes.
Tritt M, Sgouroudis E, d'Hennezel E, Albanese A, Piccirillo CA.
Diabetes. 2008 Jan;57(1):113-23. Epub 2007 Oct 10.PMID: 17928397 [PubMed - indexed for MEDLINE]Related articlesFree article
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