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    Results: 1 to 20 of 584

    1.

    Fast-evolving noncoding sequences in the human genome.

    Bird CP, Stranger BE, Liu M, Thomas DJ, Ingle CE, Beazley C, Miller W, Hurles ME, Dermitzakis ET.

    Genome Biol. 2007;8(6):R118.

    PMID:
    17578567
    [PubMed - indexed for MEDLINE]
    Free PMC Article
    2.

    Hotspots of biased nucleotide substitutions in human genes.

    Berglund J, Pollard KS, Webster MT.

    PLoS Biol. 2009 Jan 27;7(1):e26.

    PMID:
    19175294
    [PubMed - indexed for MEDLINE]
    Free PMC Article
    3.

    Comparative and evolutionary pharmacogenetics of ABCB1: complex signatures of positive selection on coding and regulatory regions.

    Wang H, Ding K, Zhang Y, Jin L, Kullo IJ, He F.

    Pharmacogenet Genomics. 2007 Aug;17(8):667-78.

    PMID:
    17622943
    [PubMed - indexed for MEDLINE]
    4.

    Analysis of sequence conservation at nucleotide resolution.

    Asthana S, Roytberg M, Stamatoyannopoulos J, Sunyaev S.

    PLoS Comput Biol. 2007 Dec;3(12):e254. Epub 2007 Nov 14.

    PMID:
    18166073
    [PubMed - indexed for MEDLINE]
    Free PMC Article
    5.

    Accelerated evolution of conserved noncoding sequences in humans.

    Prabhakar S, Noonan JP, Pääbo S, Rubin EM.

    Science. 2006 Nov 3;314(5800):786.

    PMID:
    17082449
    [PubMed - indexed for MEDLINE]
    6.

    Noncoding sequences near duplicated genes evolve rapidly.

    Kostka D, Hahn MW, Pollard KS.

    Genome Biol Evol. 2010;2:518-33. Epub 2010 Jun 29.

    PMID:
    20660939
    [PubMed - indexed for MEDLINE]
    Free PMC Article
    7.

    [A comparative analysis of regulatory regions of the transthyretin gene in the mouse, human, and chimpanzee genomes].

    Nadezhdin EV, Vinogradova TV, Sverdlov ED.

    Bioorg Khim. 2004 Jul-Aug;30(4):383-8. Russian.

    PMID:
    15469012
    [PubMed - indexed for MEDLINE]
    8.

    Understanding the recent evolution of the human genome: insights from human-chimpanzee genome comparisons.

    Kehrer-Sawatzki H, Cooper DN.

    Hum Mutat. 2007 Feb;28(2):99-130. Review.

    PMID:
    17024666
    [PubMed - indexed for MEDLINE]
    9.

    Evolutionary processes acting on candidate cis-regulatory regions in humans inferred from patterns of polymorphism and divergence.

    Torgerson DG, Boyko AR, Hernandez RD, Indap A, Hu X, White TJ, Sninsky JJ, Cargill M, Adams MD, Bustamante CD, Clark AG.

    PLoS Genet. 2009 Aug;5(8):e1000592. Epub 2009 Aug 7.

    PMID:
    19662163
    [PubMed - indexed for MEDLINE]
    Free PMC Article
    10.

    Mammalian BEX, WEX and GASP genes: coding and non-coding chimaerism sustained by gene conversion events.

    Winter EE, Ponting CP.

    BMC Evol Biol. 2005 Oct 12;5:54.

    PMID:
    16221301
    [PubMed - indexed for MEDLINE]
    Free PMC Article
    11.

    Evolutionary constraint facilitates interpretation of genetic variation in resequenced human genomes.

    Goode DL, Cooper GM, Schmutz J, Dickson M, Gonzales E, Tsai M, Karra K, Davydov E, Batzoglou S, Myers RM, Sidow A.

    Genome Res. 2010 Mar;20(3):301-10. Epub 2010 Jan 12.

    PMID:
    20067941
    [PubMed - indexed for MEDLINE]
    Free PMC Article
    12.

    Parallel patterns of evolution in the genomes and transcriptomes of humans and chimpanzees.

    Khaitovich P, Hellmann I, Enard W, Nowick K, Leinweber M, Franz H, Weiss G, Lachmann M, Pääbo S.

    Science. 2005 Sep 16;309(5742):1850-4. Epub 2005 Sep 1.

    PMID:
    16141373
    [PubMed - indexed for MEDLINE]
    13.

    Purifying selection maintains highly conserved noncoding sequences in Drosophila.

    Casillas S, Barbadilla A, Bergman CM.

    Mol Biol Evol. 2007 Oct;24(10):2222-34. Epub 2007 Jul 23.

    PMID:
    17646256
    [PubMed - indexed for MEDLINE]
    Free Article
    14.

    A genome-wide screen for noncoding elements important in primate evolution.

    Bush EC, Lahn BT.

    BMC Evol Biol. 2008 Jan 23;8:17.

    PMID:
    18215302
    [PubMed - indexed for MEDLINE]
    Free PMC Article
    15.

    Evidence for widespread degradation of gene control regions in hominid genomes.

    Keightley PD, Lercher MJ, Eyre-Walker A.

    PLoS Biol. 2005 Feb;3(2):e42. Epub 2005 Jan 25.

    PMID:
    15678168
    [PubMed - indexed for MEDLINE]
    Free PMC Article
    16.

    Genome and gene alterations by insertions and deletions in the evolution of human and chimpanzee chromosome 22.

    Volfovsky N, Oleksyk TK, Cruz KC, Truelove AL, Stephens RM, Smith MW.

    BMC Genomics. 2009 Jan 26;10:51.

    PMID:
    19171065
    [PubMed - indexed for MEDLINE]
    Free PMC Article
    17.

    Evolution of candidate transcriptional regulatory motifs since the human-chimpanzee divergence.

    Donaldson IJ, Göttgens B.

    Genome Biol. 2006;7(6):R52.

    PMID:
    16808854
    [PubMed - indexed for MEDLINE]
    Free PMC Article
    18.

    Duplication and positive selection among hominin-specific PRAME genes.

    Birtle Z, Goodstadt L, Ponting C.

    BMC Genomics. 2005 Sep 13;6:120.

    PMID:
    16159394
    [PubMed - indexed for MEDLINE]
    Free PMC Article
    19.

    Widely distributed noncoding purifying selection in the human genome.

    Asthana S, Noble WS, Kryukov G, Grant CE, Sunyaev S, Stamatoyannopoulos JA.

    Proc Natl Acad Sci U S A. 2007 Jul 24;104(30):12410-5. Epub 2007 Jul 17.

    PMID:
    17640883
    [PubMed - indexed for MEDLINE]
    Free PMC Article
    20.

    Human-specific loss of regulatory DNA and the evolution of human-specific traits.

    McLean CY, Reno PL, Pollen AA, Bassan AI, Capellini TD, Guenther C, Indjeian VB, Lim X, Menke DB, Schaar BT, Wenger AM, Bejerano G, Kingsley DM.

    Nature. 2011 Mar 10;471(7337):216-9.

    PMID:
    21390129
    [PubMed - indexed for MEDLINE]
    Free PMC Article

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