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    Results: 1 to 20 of 189

    1.

    Stopping at nothing? Some dilemmas of data monitoring in clinical trials.

    Goodman SN.

    Ann Intern Med. 2007 Jun 19;146(12):882-7.PMID: 17577008 [PubMed - indexed for MEDLINE]Related articlesFree article

    2.

    Ethical issues in stopping randomized trials early because of apparent benefit.

    Mueller PS, Montori VM, Bassler D, Koenig BA, Guyatt GH.

    Ann Intern Med. 2007 Jun 19;146(12):878-81.PMID: 17577007 [PubMed - indexed for MEDLINE]Related articlesFree article

    3.

    Stopping randomized trials early for benefit: a protocol of the Study Of Trial Policy Of Interim Truncation-2 (STOPIT-2).

    Briel M, Lane M, Montori VM, Bassler D, Glasziou P, Malaga G, Akl EA, Ferreira-Gonzalez I, Alonso-Coello P, Urrutia G, Kunz R, Culebro CR, da Silva SA, Flynn DN, Elamin MB, Strahm B, Murad MH, Djulbegovic B, Adhikari NK, Mills EJ, Gwadry-Sridhar F, Kirpalani H, Soares HP, Elnour NO, You JJ, Karanicolas PJ, Bucher HC, Lampropulos JF, Nordmann AJ, Burns KE, Mulla SM, Raatz H, Sood A, Kaur J, Bankhead CR, Mullan RJ, Nerenberg KA, Vandvik PO, Coto-Yglesias F, Schünemann H, Tuche F, Chrispim PP, Cook DJ, Lutz K, Ribic CM, Vale N, Erwin PJ, Perera R, Zhou Q, Heels-Ansdell D, Ramsay T, Walter SD, Guyatt GH.

    Trials. 2009 Jul 6;10:49.PMID: 19580665 [PubMed - indexed for MEDLINE]Related articlesFree article

    4.

    Data monitoring committees and interim monitoring guidelines.

    Freidlin B, Korn EL, George SL.

    Control Clin Trials. 1999 Oct;20(5):395-407. Review.PMID: 10503800 [PubMed - indexed for MEDLINE]Related articles

    5.

    Frequentist evaluation of group sequential clinical trial designs.

    Emerson SS, Kittelson JM, Gillen DL.

    Stat Med. 2007 Dec 10;26(28):5047-80.PMID: 17573678 [PubMed - indexed for MEDLINE]Related articles

    6.

    Randomized trials stopped early for harm in HIV/AIDS: a systematic survey.

    Mills E, Cooper C, Wu P, Rachlis B, Singh S, Guyatt GH.

    HIV Clin Trials. 2006 Jan-Feb;7(1):24-33. Review.PMID: 16684642 [PubMed - indexed for MEDLINE]Related articles

    7.

    Practical problems in interim analyses, with particular regard to estimation.

    Pocock SJ, Hughes MD.

    Control Clin Trials. 1989 Dec;10(4 Suppl):209S-221S.PMID: 2605969 [PubMed - indexed for MEDLINE]Related articles

    8.

    Monitoring of large randomised clinical trials: a new approach with Bayesian methods.

    Parmar MK, Griffiths GO, Spiegelhalter DJ, Souhami RL, Altman DG, van der Scheuren E; CHART steering committee.

    Lancet. 2001 Aug 4;358(9279):375-81.PMID: 11502318 [PubMed - indexed for MEDLINE]Related articles

    9.

    Ethics of randomised controlled trials--not yet time to give up on equipoise.

    Ashcroft RE.

    Arthritis Res Ther. 2004;6(6):237-9. Epub 2004 Sep 14.PMID: 15535836 [PubMed - indexed for MEDLINE]Related articlesFree article

    10.

    Early stopping of randomized clinical trials for overt efficacy is problematic.

    Bassler D, Montori VM, Briel M, Glasziou P, Guyatt G.

    J Clin Epidemiol. 2008 Mar;61(3):241-6. Review.PMID: 18226746 [PubMed - indexed for MEDLINE]Related articles

    11.

    Interim analysis in clinical trials.

    Armitage P.

    Stat Med. 1991 Jun;10(6):925-35; discussion 936-7.PMID: 1876782 [PubMed - indexed for MEDLINE]Related articles

    12.

    Implementing a decision-theoretic design in clinical trials: why and how?

    Palmer CR, Shahumyan H.

    Stat Med. 2007 Nov 30;26(27):4939-57.PMID: 17582801 [PubMed - indexed for MEDLINE]Related articles

    13.

    Stopping rules and estimation problems in clinical trials.

    Hughes MD, Pocock SJ.

    Stat Med. 1988 Dec;7(12):1231-42.PMID: 3231947 [PubMed - indexed for MEDLINE]Related articles

    14.

    Monitoring and reporting of the Women's Health Initiative randomized hormone therapy trials.

    Anderson GL, Kooperberg C, Geller N, Rossouw JE, Pettinger M, Prentice RL.

    Clin Trials. 2007;4(3):207-17.PMID: 17715246 [PubMed - indexed for MEDLINE]Related articles

    15.

    The independent statistician for data monitoring committees.

    DeMets DL, Fleming TR.

    Stat Med. 2004 May 30;23(10):1513-7.PMID: 15122729 [PubMed - indexed for MEDLINE]Related articles

    16.

    Data Monitoring Committees and early stopping guidelines: the Southwest Oncology Group experience.

    Crowley J, Green S, Liu PY, Wolf M.

    Stat Med. 1994 Jul 15-30;13(13-14):1391-9.PMID: 7973218 [PubMed - indexed for MEDLINE]Related articles

    17.

    A decision rule for sequential monitoring of clinical trials with a primary and supportive outcome.

    Zhao Y, Grambsch PM, Neaton JD.

    Clin Trials. 2007;4(2):140-53.PMID: 17456513 [PubMed - indexed for MEDLINE]Related articles

    18.

    [Roaming through the methodology. XIV. The premature ending of a randomized trial]

    Vandenbroucke JP.

    Ned Tijdschr Geneeskd. 1999 Jun 19;143(25):1305-8. Review. Dutch. PMID: 10416484 [PubMed - indexed for MEDLINE]Related articles

    19.

    [Monitoring the safety of participants in randomised clinical trials: basis and methods]

    Tijssen JG.

    Ned Tijdschr Geneeskd. 2008 Mar 22;152(12):674-8. Review. Dutch. PMID: 18438062 [PubMed - indexed for MEDLINE]Related articles

    20.

    The agonising negative trend in monitoring of clinical trials.

    DeMets DL, Pocock SJ, Julian DG.

    Lancet. 1999 Dec 4;354(9194):1983-8. Review.PMID: 10622312 [PubMed - indexed for MEDLINE]Related articles