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    Results: 1 to 20 of 291

    1.

    Ethical issues in stopping randomized trials early because of apparent benefit.

    Mueller PS, Montori VM, Bassler D, Koenig BA, Guyatt GH.

    Ann Intern Med. 2007 Jun 19;146(12):878-81.PMID: 17577007 [PubMed - indexed for MEDLINE]Related articlesFree article

    2.

    Early stopping of randomized clinical trials for overt efficacy is problematic.

    Bassler D, Montori VM, Briel M, Glasziou P, Guyatt G.

    J Clin Epidemiol. 2008 Mar;61(3):241-6. Review.PMID: 18226746 [PubMed - indexed for MEDLINE]Related articles

    3.

    Stopping randomized trials early for benefit: a protocol of the Study Of Trial Policy Of Interim Truncation-2 (STOPIT-2).

    Briel M, Lane M, Montori VM, Bassler D, Glasziou P, Malaga G, Akl EA, Ferreira-Gonzalez I, Alonso-Coello P, Urrutia G, Kunz R, Culebro CR, da Silva SA, Flynn DN, Elamin MB, Strahm B, Murad MH, Djulbegovic B, Adhikari NK, Mills EJ, Gwadry-Sridhar F, Kirpalani H, Soares HP, Elnour NO, You JJ, Karanicolas PJ, Bucher HC, Lampropulos JF, Nordmann AJ, Burns KE, Mulla SM, Raatz H, Sood A, Kaur J, Bankhead CR, Mullan RJ, Nerenberg KA, Vandvik PO, Coto-Yglesias F, Schünemann H, Tuche F, Chrispim PP, Cook DJ, Lutz K, Ribic CM, Vale N, Erwin PJ, Perera R, Zhou Q, Heels-Ansdell D, Ramsay T, Walter SD, Guyatt GH.

    Trials. 2009 Jul 6;10:49.PMID: 19580665 [PubMed - indexed for MEDLINE]Related articlesFree article

    4.

    Stopping at nothing? Some dilemmas of data monitoring in clinical trials.

    Goodman SN.

    Ann Intern Med. 2007 Jun 19;146(12):882-7.PMID: 17577008 [PubMed - indexed for MEDLINE]Related articlesFree article

    5.

    Randomized, controlled trials as minimal risk: an ethical analysis.

    Morris MC, Nelson RM.

    Crit Care Med. 2007 Mar;35(3):940-4.PMID: 17255879 [PubMed - indexed for MEDLINE]Related articles

    6.

    Are distinctive ethical principles required for cluster randomized controlled trials?

    Hutton JL.

    Stat Med. 2001 Feb 15;20(3):473-88.PMID: 11180314 [PubMed - indexed for MEDLINE]Related articles

    7.

    [Ethical controversies on the use of placebo as control treatment in clinical trials in neurology]

    Lahuerta J, Gutiérrez Rivas E, Frías J, Gracia D, Dal-Ré R.

    Neurologia. 2007 Mar;22(2):106-13. Review. Spanish. PMID: 17323236 [PubMed - indexed for MEDLINE]Related articlesFree article

    8.

    Ethical considerations in clinical neuroscience. Current concepts in neuroclinical trials.

    Alves WA, Macciocchi SN.

    Stroke. 1996 Oct;27(10):1903-9. Review.PMID: 8841351 [PubMed - indexed for MEDLINE]Related articlesFree article

    9.

    Microbicide research in developing countries: have we given the ethical concerns due consideration?

    Moodley K.

    BMC Med Ethics. 2007 Sep 19;8:10.PMID: 17877834 [PubMed - indexed for MEDLINE]Related articlesFree article

    10.

    Members of research ethics committees accepted a modification of the randomized consent design.

    Schellings R, Kessels AG, Ter Riet G, Kleijnen J, Leffers P, Knottnerus JA, Sturmans F.

    J Clin Epidemiol. 2005 Jun;58(6):589-94.PMID: 15878472 [PubMed - indexed for MEDLINE]Related articles

    11.

    Money and distorted ethical judgments about research: ethical assessment of the TeGenero TGN1412 trial.

    Emanuel EJ, Miller FG.

    Am J Bioeth. 2007 Feb;7(2):76-81. Review.PMID: 17366206 [PubMed - indexed for MEDLINE]Related articles

    12.

    Principles of early stopping of randomized trials for efficacy: a critique of equipoise and an alternative nonexploitation ethical framework.

    Buchanan D, Miller FG.

    Kennedy Inst Ethics J. 2005 Jun;15(2):161-78.PMID: 16149206 [PubMed - indexed for MEDLINE]Related articles

    13.

    Clinical research with healthy volunteers: an ethical framework.

    Miller FG.

    J Investig Med. 2003 Feb;51 Suppl 1:S2-5.PMID: 12664947 [PubMed - indexed for MEDLINE]Related articles

    14.

    Clinical trials in neonates: ethical issues.

    Allmark P, Spedding M.

    Semin Fetal Neonatal Med. 2007 Aug;12(4):318-23. Epub 2007 Mar 9. Review.PMID: 17350356 [PubMed - indexed for MEDLINE]Related articles

    15.

    Equipoise, design bias, and randomized controlled trials: the elusive ethics of new drug development.

    Fries JF, Krishnan E.

    Arthritis Res Ther. 2004;6(3):R250-5. Epub 2004 Mar 18.PMID: 15142271 [PubMed - indexed for MEDLINE]Related articlesFree article

    16.

    ECNP consensus meeting. Bipolar depression. Nice, March 2007.

    Goodwin GM, Anderson I, Arango C, Bowden CL, Henry C, Mitchell PB, Nolen WA, Vieta E, Wittchen HU.

    Eur Neuropsychopharmacol. 2008 Jul;18(7):535-49. Epub 2008 May 23. Review.PMID: 18501566 [PubMed - indexed for MEDLINE]Related articles

    17.

    Ethical assessment of industry-sponsored clinical trials: a case analysis.

    Miller FG, Shorr AF.

    Chest. 2002 Apr;121(4):1337-42.PMID: 11948071 [PubMed - indexed for MEDLINE]Related articlesFree article

    18.

    Placebo effect and randomized clinical trials.

    Elander G, Hermerén G.

    Theor Med. 1995 Jun;16(2):171-82.PMID: 7570396 [PubMed - indexed for MEDLINE]Related articles

    19.

    Methodological quality and reporting of ethical requirements in phase III cancer trials.

    Tuech JJ, Pessaux P, Moutel G, Thoma V, Schraub S, Herve C.

    J Med Ethics. 2005 May;31(5):251-5.PMID: 15863678 [PubMed - indexed for MEDLINE]Related articlesFree article

    20.

    Randomized trials stopped early for harm in HIV/AIDS: a systematic survey.

    Mills E, Cooper C, Wu P, Rachlis B, Singh S, Guyatt GH.

    HIV Clin Trials. 2006 Jan-Feb;7(1):24-33. Review.PMID: 16684642 [PubMed - indexed for MEDLINE]Related articles

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