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    Results: 1 to 20 of 358

    1.

    Metallothionein prevents high-fat diet induced cardiac contractile dysfunction: role of peroxisome proliferator activated receptor gamma coactivator 1alpha and mitochondrial biogenesis.

    Dong F, Li Q, Sreejayan N, Nunn JM, Ren J.

    Diabetes. 2007 Sep;56(9):2201-12. Epub 2007 Jun 15.PMID: 17575086 [PubMed - indexed for MEDLINE]Related articlesFree article

    2.

    Hypertrophic cardiomyopathy in high-fat diet-induced obesity: role of suppression of forkhead transcription factor and atrophy gene transcription.

    Fang CX, Dong F, Thomas DP, Ma H, He L, Ren J.

    Am J Physiol Heart Circ Physiol. 2008 Sep;295(3):H1206-H1215. Epub 2008 Jul 18.PMID: 18641278 [PubMed - indexed for MEDLINE]Related articlesFree article

    3.

    Metallothionein abrogates GTP cyclohydrolase I inhibition-induced cardiac contractile and morphological defects: role of mitochondrial biogenesis.

    Ceylan-Isik AF, Guo KK, Carlson EC, Privratsky JR, Liao SJ, Cai L, Chen AF, Ren J.

    Hypertension. 2009 Jun;53(6):1023-31. Epub 2009 Apr 27.PMID: 19398661 [PubMed - indexed for MEDLINE]Related articles

    4.

    Metallothionein alleviates cardiac contractile dysfunction induced by insulin resistance: role of Akt phosphorylation, PTB1B, PPARgamma and c-Jun.

    Fang CX, Dong F, Ren BH, Epstein PN, Ren J.

    Diabetologia. 2005 Nov;48(11):2412-21. Epub 2005 Sep 20.PMID: 16172869 [PubMed - indexed for MEDLINE]Related articles

    5.

    Interaction between high-fat diet and alcohol dehydrogenase on ethanol-elicited cardiac depression in murine myocytes.

    Ren J.

    Obesity (Silver Spring). 2007 Dec;15(12):2932-41.PMID: 18198301 [PubMed - indexed for MEDLINE]Related articles

    6.

    Cardiac overexpression of metallothionein attenuates chronic alcohol intake-induced cardiomyocyte contractile dysfunction.

    Li Q, Ren J.

    Cardiovasc Toxicol. 2006;6(3-4):173-82.PMID: 17347528 [PubMed - indexed for MEDLINE]Related articles

    7.

    Cardiac overexpression of catalase rescues cardiac contractile dysfunction induced by insulin resistance: Role of oxidative stress, protein carbonyl formation and insulin sensitivity.

    Dong F, Fang CX, Yang X, Zhang X, Lopez FL, Ren J.

    Diabetologia. 2006 Jun;49(6):1421-33. Epub 2006 Apr 4.PMID: 16586065 [PubMed - indexed for MEDLINE]Related articles

    8.

    Metallothionein antagonizes aging-induced cardiac contractile dysfunction: role of PTP1B, insulin receptor tyrosine phosphorylation and Akt.

    Fang CX, Doser TA, Yang X, Sreejayan N, Ren J.

    Aging Cell. 2006 Apr;5(2):177-85.PMID: 16626396 [PubMed - indexed for MEDLINE]Related articles

    9.

    Metallothionein alleviates glutathione depletion-induced oxidative cardiomyopathy in murine hearts.

    Ren J, Privratsky JR, Yang X, Dong F, Carlson EC.

    Crit Care Med. 2008 Jul;36(7):2106-16.PMID: 18552690 [PubMed - indexed for MEDLINE]Related articles

    10.

    Cardiac-specific induction of the transcriptional coactivator peroxisome proliferator-activated receptor gamma coactivator-1alpha promotes mitochondrial biogenesis and reversible cardiomyopathy in a developmental stage-dependent manner.

    Russell LK, Mansfield CM, Lehman JJ, Kovacs A, Courtois M, Saffitz JE, Medeiros DM, Valencik ML, McDonald JA, Kelly DP.

    Circ Res. 2004 Mar 5;94(4):525-33. Epub 2004 Jan 15.PMID: 14726475 [PubMed - indexed for MEDLINE]Related articlesFree article

    11.

    High-fat diet-induced obesity leads to resistance to leptin-induced cardiomyocyte contractile response.

    Ren J, Zhu BH, Relling DP, Esberg LB, Ceylan-Isik AF.

    Obesity (Silver Spring). 2008 Nov;16(11):2417-23. Epub 2008 Aug 14.PMID: 18719678 [PubMed - indexed for MEDLINE]Related articles

    12.

    Sex difference in cardiomyocyte function in normal and metallothionein transgenic mice: the effect of diabetes mellitus.

    Ceylan-Isik AF, LaCour KH, Ren J.

    J Appl Physiol. 2006 May;100(5):1638-46. Epub 2006 Jan 12.PMID: 16410376 [PubMed - indexed for MEDLINE]Related articlesFree article

    13.

    High-fat diet-induced juvenile obesity leads to cardiomyocyte dysfunction and upregulation of Foxo3a transcription factor independent of lipotoxicity and apoptosis.

    Relling DP, Esberg LB, Fang CX, Johnson WT, Murphy EJ, Carlson EC, Saari JT, Ren J.

    J Hypertens. 2006 Mar;24(3):549-61.PMID: 16467659 [PubMed - indexed for MEDLINE]Related articles

    14.

    Dietary interaction of high fat and marginal copper deficiency on cardiac contractile function.

    Relling DP, Esberg LB, Johnson WT, Murphy EJ, Carlson EC, Lukaski HC, Saari JT, Ren J.

    Obesity (Silver Spring). 2007 May;15(5):1242-57.PMID: 17495201 [PubMed - indexed for MEDLINE]Related articles

    15.

    Peroxisome proliferator activator receptor gamma coactivator-1 expression is reduced in obesity: potential pathogenic role of saturated fatty acids and p38 mitogen-activated protein kinase activation.

    Crunkhorn S, Dearie F, Mantzoros C, Gami H, da Silva WS, Espinoza D, Faucette R, Barry K, Bianco AC, Patti ME.

    J Biol Chem. 2007 May 25;282(21):15439-50. Epub 2007 Apr 6.PMID: 17416903 [PubMed - indexed for MEDLINE]Related articlesFree article

    16.

    Increased glucose uptake and oxidation in mouse hearts prevent high fatty acid oxidation but cause cardiac dysfunction in diet-induced obesity.

    Yan J, Young ME, Cui L, Lopaschuk GD, Liao R, Tian R.

    Circulation. 2009 Jun 2;119(21):2818-28. Epub 2009 May 18.PMID: 19451348 [PubMed - indexed for MEDLINE]Related articles

    17.

    The transcriptional coactivator PGC-1alpha is essential for maximal and efficient cardiac mitochondrial fatty acid oxidation and lipid homeostasis.

    Lehman JJ, Boudina S, Banke NH, Sambandam N, Han X, Young DM, Leone TC, Gross RW, Lewandowski ED, Abel ED, Kelly DP.

    Am J Physiol Heart Circ Physiol. 2008 Jul;295(1):H185-96. Epub 2008 May 16.PMID: 18487436 [PubMed - indexed for MEDLINE]Related articlesFree article

    18.

    Catalase alleviates cardiomyocyte dysfunction in diabetes: role of Akt, Forkhead transcriptional factor and silent information regulator 2.

    Turdi S, Li Q, Lopez FL, Ren J.

    Life Sci. 2007 Aug 23;81(11):895-905. Epub 2007 Aug 14.PMID: 17765928 [PubMed - indexed for MEDLINE]Related articles

    19.

    Cardiac overexpression of alcohol dehydrogenase exacerbates cardiac contractile dysfunction, lipid peroxidation, and protein damage after chronic ethanol ingestion.

    Hintz KK, Relling DP, Saari JT, Borgerding AJ, Duan J, Ren BH, Kato K, Epstein PN, Ren J.

    Alcohol Clin Exp Res. 2003 Jul;27(7):1090-8.PMID: 12878915 [PubMed - indexed for MEDLINE]Related articles

    20.

    Adipose mitochondrial biogenesis is suppressed in db/db and high-fat diet-fed mice and improved by rosiglitazone.

    Rong JX, Qiu Y, Hansen MK, Zhu L, Zhang V, Xie M, Okamoto Y, Mattie MD, Higashiyama H, Asano S, Strum JC, Ryan TE.

    Diabetes. 2007 Jul;56(7):1751-60. Epub 2007 Apr 24.PMID: 17456854 [PubMed - indexed for MEDLINE]Related articlesFree article

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