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    Results: 1 to 20 of 224

    1.

    Gene expression variation in Down's syndrome mice allows prioritization of candidate genes.

    Sultan M, Piccini I, Balzereit D, Herwig R, Saran NG, Lehrach H, Reeves RH, Yaspo ML.

    Genome Biol. 2007;8(5):R91.

    PMID:
    17531092
    [PubMed - indexed for MEDLINE]
    Free PMC Article
    2.

    Transcript level alterations reflect gene dosage effects across multiple tissues in a mouse model of down syndrome.

    Kahlem P, Sultan M, Herwig R, Steinfath M, Balzereit D, Eppens B, Saran NG, Pletcher MT, South ST, Stetten G, Lehrach H, Reeves RH, Yaspo ML.

    Genome Res. 2004 Jul;14(7):1258-67.

    PMID:
    15231742
    [PubMed - indexed for MEDLINE]
    Free PMC Article
    3.

    Developmental instability of the cerebellum and its relevance to Down syndrome.

    Shapiro BL.

    J Neural Transm Suppl. 2001;(61):11-34. Review.

    PMID:
    11771737
    [PubMed - indexed for MEDLINE]
    4.

    Segmental trisomy of chromosome 17: a mouse model of human aneuploidy syndromes.

    Vacík T, Ort M, Gregorová S, Strnad P, Blatny R, Conte N, Bradley A, Bures J, Forejt J.

    Proc Natl Acad Sci U S A. 2005 Mar 22;102(12):4500-5. Epub 2005 Mar 8.

    PMID:
    15755806
    [PubMed - indexed for MEDLINE]
    Free PMC Article
    5.

    Gene expression signature of cerebellar hypoplasia in a mouse model of Down syndrome during postnatal development.

    Laffaire J, Rivals I, Dauphinot L, Pasteau F, Wehrle R, Larrat B, Vitalis T, Moldrich RX, Rossier J, Sinkus R, Herault Y, Dusart I, Potier MC.

    BMC Genomics. 2009 Mar 30;10:138.

    PMID:
    19331679
    [PubMed - indexed for MEDLINE]
    Free PMC Article
    6.

    Gene expression from the aneuploid chromosome in a trisomy mouse model of down syndrome.

    Lyle R, Gehrig C, Neergaard-Henrichsen C, Deutsch S, Antonarakis SE.

    Genome Res. 2004 Jul;14(7):1268-74.

    PMID:
    15231743
    [PubMed - indexed for MEDLINE]
    Free PMC Article
    7.

    The mouse brain transcriptome by SAGE: differences in gene expression between P30 brains of the partial trisomy 16 mouse model of Down syndrome (Ts65Dn) and normals.

    Chrast R, Scott HS, Papasavvas MP, Rossier C, Antonarakis ES, Barras C, Davisson MT, Schmidt C, Estivill X, Dierssen M, Pritchard M, Antonarakis SE.

    Genome Res. 2000 Dec;10(12):2006-21.

    PMID:
    11116095
    [PubMed - indexed for MEDLINE]
    Free PMC Article
    8.

    Dosage-dependent over-expression of genes in the trisomic region of Ts1Cje mouse model for Down syndrome.

    Amano K, Sago H, Uchikawa C, Suzuki T, Kotliarova SE, Nukina N, Epstein CJ, Yamakawa K.

    Hum Mol Genet. 2004 Jul 1;13(13):1333-40. Epub 2004 May 11.

    PMID:
    15138197
    [PubMed - indexed for MEDLINE]
    Free Article
    9.

    Understanding mental retardation in Down's syndrome using trisomy 16 mouse models.

    Galdzicki Z, Siarey RJ.

    Genes Brain Behav. 2003 Jun;2(3):167-78. Review.

    PMID:
    12931790
    [PubMed - indexed for MEDLINE]
    10.

    Highly penetrant myeloproliferative disease in the Ts65Dn mouse model of Down syndrome.

    Kirsammer G, Jilani S, Liu H, Davis E, Gurbuxani S, Le Beau MM, Crispino JD.

    Blood. 2008 Jan 15;111(2):767-75. Epub 2007 Sep 27.

    PMID:
    17901249
    [PubMed - indexed for MEDLINE]
    Free PMC Article
    11.

    Mental retardation in Down syndrome: from gene dosage imbalance to molecular and cellular mechanisms.

    Rachidi M, Lopes C.

    Neurosci Res. 2007 Dec;59(4):349-69. Epub 2007 Aug 15. Review.

    PMID:
    17897742
    [PubMed - indexed for MEDLINE]
    12.

    Tumour angiogenesis is reduced in the Tc1 mouse model of Down's syndrome.

    Reynolds LE, Watson AR, Baker M, Jones TA, D'Amico G, Robinson SD, Joffre C, Garrido-Urbani S, Rodriguez-Manzaneque JC, Martino-Echarri E, Aurrand-Lions M, Sheer D, Dagna-Bricarelli F, Nizetic D, McCabe CJ, Turnell AS, Kermorgant S, Imhof BA, Adams R, Fisher EM, Tybulewicz VL, Hart IR, Hodivala-Dilke KM.

    Nature. 2010 Jun 10;465(7299):813-7. Erratum in: Nature. 2010 Jul 15;466(7304):398.

    PMID:
    20535211
    [PubMed - indexed for MEDLINE]
    13.

    Mental retardation and associated neurological dysfunctions in Down syndrome: a consequence of dysregulation in critical chromosome 21 genes and associated molecular pathways.

    Rachidi M, Lopes C.

    Eur J Paediatr Neurol. 2008 May;12(3):168-82. Epub 2007 Oct 22. Review.

    PMID:
    17933568
    [PubMed - indexed for MEDLINE]
    14.

    Differential effects of trisomy on brain shape and volume in related aneuploid mouse models.

    Aldridge K, Reeves RH, Olson LE, Richtsmeier JT.

    Am J Med Genet A. 2007 May 15;143A(10):1060-70.

    PMID:
    17431903
    [PubMed - indexed for MEDLINE]
    Free PMC Article
    15.

    Trisomy for the Down syndrome 'critical region' is necessary but not sufficient for brain phenotypes of trisomic mice.

    Olson LE, Roper RJ, Sengstaken CL, Peterson EA, Aquino V, Galdzicki Z, Siarey R, Pletnikov M, Moran TH, Reeves RH.

    Hum Mol Genet. 2007 Apr 1;16(7):774-82. Epub 2007 Mar 5.

    PMID:
    17339268
    [PubMed - indexed for MEDLINE]
    Free Article
    16.

    Discovery and genetic localization of Down syndrome cerebellar phenotypes using the Ts65Dn mouse.

    Baxter LL, Moran TH, Richtsmeier JT, Troncoso J, Reeves RH.

    Hum Mol Genet. 2000 Jan 22;9(2):195-202.

    PMID:
    10607830
    [PubMed - indexed for MEDLINE]
    Free Article
    17.

    Global disruption of the cerebellar transcriptome in a Down syndrome mouse model.

    Saran NG, Pletcher MT, Natale JE, Cheng Y, Reeves RH.

    Hum Mol Genet. 2003 Aug 15;12(16):2013-9.

    PMID:
    12913072
    [PubMed - indexed for MEDLINE]
    Free Article
    18.

    Gene expression variation increase in trisomy 21 tissues.

    Chou CY, Liu LY, Chen CY, Tsai CH, Hwa HL, Chang LY, Lin YS, Hsieh FJ.

    Mamm Genome. 2008 Jun;19(6):398-405. Epub 2008 Jul 2.

    PMID:
    18594911
    [PubMed - indexed for MEDLINE]
    19.

    Dysregulation of gene expression in mouse trisomy 16, an animal model of Down syndrome.

    Holtzman DM, Bayney RM, Li YW, Khosrovi H, Berger CN, Epstein CJ, Mobley WC.

    EMBO J. 1992 Feb;11(2):619-27.

    PMID:
    1371464
    [PubMed - indexed for MEDLINE]
    Free PMC Article
    20.

    Down syndrome mouse models Ts65Dn, Ts1Cje, and Ms1Cje/Ts65Dn exhibit variable severity of cerebellar phenotypes.

    Olson LE, Roper RJ, Baxter LL, Carlson EJ, Epstein CJ, Reeves RH.

    Dev Dyn. 2004 Jul;230(3):581-9.

    PMID:
    15188443
    [PubMed - indexed for MEDLINE]
    Free Article

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