PubMed

Variation in TCF7L2 influences therapeutic response to sulfonylureas: a GoDARTs study.

Pearson ER, Donnelly LA, Kimber C, Whitley A, Doney AS, McCarthy MI, Hattersley AT, Morris AD, Palmer CN.

Diabetes. 2007 Aug;56(8):2178-82. Epub 2007 May 22.PMID: 17519421 [PubMed - indexed for MEDLINE]Related articlesFree article

Reduced-function SLC22A1 polymorphisms encoding organic cation transporter 1 and glycemic response to metformin: a GoDARTS study.

Zhou K, Donnelly LA, Kimber CH, Donnan PT, Doney AS, Leese G, Hattersley AT, McCarthy MI, Morris AD, Palmer CN, Pearson ER.

Diabetes. 2009 Jun;58(6):1434-9. Epub 2009 Mar 31.PMID: 19336679 [PubMed - indexed for MEDLINE]Related articlesFree article

TCF7L2 in the Go-DARTS study: evidence for a gene dose effect on both diabetes susceptibility and control of glucose levels.

Kimber CH, Doney AS, Pearson ER, McCarthy MI, Hattersley AT, Leese GP, Morris AD, Palmer CN.

Diabetologia. 2007 Jun;50(6):1186-91. Epub 2007 Apr 11.PMID: 17429603 [PubMed - indexed for MEDLINE]Related articles

Common variants in the TCF7L2 gene are strongly associated with type 2 diabetes mellitus in the Indian population.

Chandak GR, Janipalli CS, Bhaskar S, Kulkarni SR, Mohankrishna P, Hattersley AT, Frayling TM, Yajnik CS.

Diabetologia. 2007 Jan;50(1):63-7. Epub 2006 Nov 9.PMID: 17093941 [PubMed - indexed for MEDLINE]Related articles

Association study of the genetic polymorphisms of the transcription factor 7-like 2 (TCF7L2) gene and type 2 diabetes in the Chinese population.

Chang YC, Chang TJ, Jiang YD, Kuo SS, Lee KC, Chiu KC, Chuang LM.

Diabetes. 2007 Oct;56(10):2631-7. Epub 2007 Jun 19.PMID: 17579206 [PubMed - indexed for MEDLINE]Related articlesFree article

The rs12255372(G/T) and rs7903146(C/T) polymorphisms of the TCF7L2 gene are associated with type 2 diabetes mellitus in Asian Indians.

Bodhini D, Radha V, Dhar M, Narayani N, Mohan V.

Metabolism. 2007 Sep;56(9):1174-8.PMID: 17697858 [PubMed - indexed for MEDLINE]Related articles

Association of variants of the TCF7L2 gene with increases in the risk of type 2 diabetes and the proinsulin:insulin ratio in the Spanish population.

González-Sánchez JL, Martínez-Larrad MT, Zabena C, Pérez-Barba M, Serrano-Ríos M.

Diabetologia. 2008 Nov;51(11):1993-7. Epub 2008 Aug 19.PMID: 18712344 [PubMed - indexed for MEDLINE]Related articles

Variants of transcription factor 7-like 2 (TCF7L2) gene predict conversion to type 2 diabetes in the Finnish Diabetes Prevention Study and are associated with impaired glucose regulation and impaired insulin secretion.

Wang J, Kuusisto J, Vänttinen M, Kuulasmaa T, Lindström J, Tuomilehto J, Uusitupa M, Laakso M.

Diabetologia. 2007 Jun;50(6):1192-200. Epub 2007 Apr 17.PMID: 17437080 [PubMed - indexed for MEDLINE]Related articles

Risk of mortality and adverse cardiovascular outcomes in type 2 diabetes: a comparison of patients treated with sulfonylureas and metformin.

Evans JM, Ogston SA, Emslie-Smith A, Morris AD.

Diabetologia. 2006 May;49(5):930-6. Epub 2006 Mar 9.PMID: 16525843 [PubMed - indexed for MEDLINE]Related articles

Association of TCF7L2 polymorphism with diabetes mellitus, metabolic syndrome, and markers of beta cell function and insulin resistance in a population-based sample of Emirati subjects.

Saadi H, Nagelkerke N, Carruthers SG, Benedict S, Abdulkhalek S, Reed R, Lukic M, Nicholls MG.

Diabetes Res Clin Pract. 2008 Jun;80(3):392-8. Epub 2008 Feb 20.PMID: 18282631 [PubMed - indexed for MEDLINE]Related articles

TCF7L2 polymorphisms and progression to diabetes in the Diabetes Prevention Program.

Florez JC, Jablonski KA, Bayley N, Pollin TI, de Bakker PI, Shuldiner AR, Knowler WC, Nathan DM, Altshuler D; Diabetes Prevention Program Research Group.

N Engl J Med. 2006 Jul 20;355(3):241-50.PMID: 16855264 [PubMed - indexed for MEDLINE]Related articlesFree article

Whole-grain consumption and transcription factor-7-like 2 ( TCF7L2) rs7903146: gene-diet interaction in modulating type 2 diabetes risk.

Fisher E, Boeing H, Fritsche A, Doering F, Joost HG, Schulze MB.

Br J Nutr. 2009 Feb;101(4):478-81. Epub 2008 Jul 17.PMID: 19149908 [PubMed - indexed for MEDLINE]Related articles

Variants of the TCF7L2 gene are associated with beta cell dysfunction and confer an increased risk of type 2 diabetes mellitus in the ULSAM cohort of Swedish elderly men.

Dahlgren A, Zethelius B, Jensevik K, Syvänen AC, Berne C; ULSAM Cohort.

Diabetologia. 2007 Sep;50(9):1852-7. Epub 2007 Jul 6.PMID: 17618413 [PubMed - indexed for MEDLINE]Related articles

A genetic variation of the transcription factor 7-like 2 gene is associated with risk of type 2 diabetes in the Japanese population.

Horikoshi M, Hara K, Ito C, Nagai R, Froguel P, Kadowaki T.

Diabetologia. 2007 Apr;50(4):747-51. Epub 2007 Jan 24.PMID: 17245589 [PubMed - indexed for MEDLINE]Related articles

A variant of the transcription factor 7-like 2 (TCF7L2) gene and the risk of posttransplantation diabetes mellitus in renal allograft recipients.

Kang ES, Kim MS, Kim YS, Hur KY, Han SJ, Nam CM, Ahn CW, Cha BS, Kim SI, Lee HC.

Diabetes Care. 2008 Jan;31(1):63-8. Epub 2007 Oct 12.PMID: 17934151 [PubMed - indexed for MEDLINE]Related articlesFree article

Common variants of the TCF7L2 gene are associated with increased risk of type 2 diabetes mellitus in a UK-resident South Asian population.

Rees SD, Bellary S, Britten AC, O'Hare JP, Kumar S, Barnett AH, Kelly MA.

BMC Med Genet. 2008 Feb 21;9:8.PMID: 18291022 [PubMed - indexed for MEDLINE]Related articlesFree article

Replication study for the association of TCF7L2 with susceptibility to type 2 diabetes in a Japanese population.

Hayashi T, Iwamoto Y, Kaku K, Hirose H, Maeda S.

Diabetologia. 2007 May;50(5):980-4. Epub 2007 Mar 6.PMID: 17340123 [PubMed - indexed for MEDLINE]Related articles

Disparate genetic influences on polycystic ovary syndrome (PCOS) and type 2 diabetes revealed by a lack of association between common variants within the TCF7L2 gene and PCOS.

Barber TM, Bennett AJ, Groves CJ, Sovio U, Ruokonen A, Martikainen H, Pouta A, Hartikainen AL, Elliott P, Wass JA, Järvelin MR, Zeggini E, Franks S, McCarthy MI.

Diabetologia. 2007 Nov;50(11):2318-22. Epub 2007 Sep 6.PMID: 17805508 [PubMed - indexed for MEDLINE]Related articles

Exon sequencing and association analysis of polymorphisms in TCF7L2 with type 2 diabetes in a Chinese population.

Ren Q, Han XY, Wang F, Zhang XY, Han LC, Luo YY, Zhou XH, Ji LN.

Diabetologia. 2008 Jul;51(7):1146-52. Epub 2008 May 21.PMID: 18493736 [PubMed - indexed for MEDLINE]Related articles

TCF7L2 variant genotypes and type 2 diabetes risk in Brazil: significant association, but not a significant tool for risk stratification in the general population.

Marquezine GF, Pereira AC, Sousa AG, Mill JG, Hueb WA, Krieger JE.

BMC Med Genet. 2008 Dec 4;9:106.PMID: 19055834 [PubMed - indexed for MEDLINE]Related articlesFree article