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    Results: 1 to 20 of 147

    1.

    Monitoring of gene knockouts: genome-wide profiling of conditionally essential genes.

    Smith LK, Gomez MJ, Shatalin KY, Lee H, Neyfakh AA.

    Genome Biol. 2007;8(5):R87.

    PMID:
    17519022
    [PubMed - indexed for MEDLINE]
    Free PMC Article
    3.

    Bacterial targets and antibiotics: genome-based drug discovery.

    Gray CP, Keck W.

    Cell Mol Life Sci. 1999 Nov 30;56(9-10):779-87. Review.

    PMID:
    11212338
    [PubMed - indexed for MEDLINE]
    4.

    Rational identification of new antibacterial drug targets that are essential for viability using a genomics-based approach.

    Chalker AF, Lunsford RD.

    Pharmacol Ther. 2002 Jul;95(1):1-20. Review.

    PMID:
    12163125
    [PubMed - indexed for MEDLINE]
    5.

    Functional genomics in antibacterial drug discovery.

    Freiberg C, Brötz-Oesterhelt H.

    Drug Discov Today. 2005 Jul 1;10(13):927-35. Review.

    PMID:
    15993812
    [PubMed - indexed for MEDLINE]
    6.

    Streptococcus pneumoniae as a genomics platform for broad-spectrum antibiotic discovery.

    Glass JI, Belanger AE, Robertson GT.

    Curr Opin Microbiol. 2002 Jun;5(3):338-42. Review.

    PMID:
    12057692
    [PubMed - indexed for MEDLINE]
    7.

    Genome-wide screening of genes affecting glycogen metabolism in Escherichia coli K-12.

    Eydallin G, Viale AM, Morán-Zorzano MT, Muñoz FJ, Montero M, Baroja-Fernández E, Pozueta-Romero J.

    FEBS Lett. 2007 Jun 26;581(16):2947-53. Epub 2007 May 25.

    PMID:
    17543954
    [PubMed - indexed for MEDLINE]
    8.

    How essential are nonessential genes?

    Fang G, Rocha E, Danchin A.

    Mol Biol Evol. 2005 Nov;22(11):2147-56. Epub 2005 Jul 13.

    PMID:
    16014871
    [PubMed - indexed for MEDLINE]
    Free Article
    9.

    Use of genomics to select antibacterial targets.

    Pucci MJ.

    Biochem Pharmacol. 2006 Mar 30;71(7):1066-72. Epub 2006 Jan 18. Review.

    PMID:
    16412986
    [PubMed - indexed for MEDLINE]
    10.

    The role of genomics in the discovery of novel targets for antibiotic therapy.

    Ji Y.

    Pharmacogenomics. 2002 May;3(3):315-23. Review.

    PMID:
    12052140
    [PubMed - indexed for MEDLINE]
    11.

    Black holes, antivirulence genes, and gene inactivation in the evolution of bacterial pathogens.

    Maurelli AT.

    FEMS Microbiol Lett. 2007 Feb;267(1):1-8. Review.

    PMID:
    17233672
    [PubMed - indexed for MEDLINE]
    12.

    Transposon-based approaches to identify essential bacterial genes.

    Judson N, Mekalanos JJ.

    Trends Microbiol. 2000 Nov;8(11):521-6. Review.

    PMID:
    11121763
    [PubMed - indexed for MEDLINE]
    13.

    Transposon-based strategies for the identification of essential bacterial genes.

    Reznikoff WS, Winterberg KM.

    Methods Mol Biol. 2008;416:13-26. Review.

    PMID:
    18392958
    [PubMed - indexed for MEDLINE]
    14.

    Novel targets for the future development of antibacterial agents.

    McDevitt D, Payne DJ, Holmes DJ, Rosenberg M.

    Symp Ser Soc Appl Microbiol. 2002;(31):28S-34S. Review.

    PMID:
    12481826
    [PubMed - indexed for MEDLINE]
    15.

    Antibiotic resistance genes from the environment: a perspective through newly identified antibiotic resistance mechanisms in the clinical setting.

    Cantón R.

    Clin Microbiol Infect. 2009 Jan;15 Suppl 1:20-5. Review.

    PMID:
    19220348
    [PubMed - indexed for MEDLINE]
    16.

    Detection of 140 clinically relevant antibiotic-resistance genes in the plasmid metagenome of wastewater treatment plant bacteria showing reduced susceptibility to selected antibiotics.

    Szczepanowski R, Linke B, Krahn I, Gartemann KH, Gützkow T, Eichler W, Pühler A, Schlüter A.

    Microbiology. 2009 Jul;155(Pt 7):2306-19. Epub 2009 Apr 23.

    PMID:
    19389756
    [PubMed - indexed for MEDLINE]
    Free Article
    17.

    High-throughput, kingdom-wide prediction and annotation of bacterial non-coding RNAs.

    Livny J, Teonadi H, Livny M, Waldor MK.

    PLoS One. 2008 Sep 12;3(9):e3197. Erratum in: PLoS ONE. 2008;3(11). doi: 10.1371/annotation/a03e1870-1dd7-4c16-8c46-2268eeb2a50a.

    PMID:
    18787707
    [PubMed - indexed for MEDLINE]
    Free PMC Article
    18.

    The impact of transcriptome and proteome analyses on antibiotic drug discovery.

    Freiberg C, Brötz-Oesterhelt H, Labischinski H.

    Curr Opin Microbiol. 2004 Oct;7(5):451-9. Review.

    PMID:
    15451499
    [PubMed - indexed for MEDLINE]
    19.

    Antibiotics and the post-genome revolution.

    Amini S, Tavazoie S.

    Curr Opin Microbiol. 2011 Oct;14(5):513-8. Epub 2011 Aug 3. Review.

    PMID:
    21816663
    [PubMed - indexed for MEDLINE]
    20.

    Microbial fitness and genome dynamics.

    Tønjum T, Seeberg E.

    Trends Microbiol. 2001 Aug;9(8):356-8. Review. No abstract available.

    PMID:
    11519528
    [PubMed - indexed for MEDLINE]

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