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    Results: 1 to 20 of 136

    1.

    5-aminoimidazole-4-carboxamide 1-beta-D-ribofuranoside acutely stimulates skeletal muscle 2-deoxyglucose uptake in healthy men.

    Cuthbertson DJ, Babraj JA, Mustard KJ, Towler MC, Green KA, Wackerhage H, Leese GP, Baar K, Thomason-Hughes M, Sutherland C, Hardie DG, Rennie MJ.

    Diabetes. 2007 Aug;56(8):2078-84. Epub 2007 May 18.PMID: 17513706 [PubMed - indexed for MEDLINE]Related articlesFree article

    2.

    Blunting of AICAR-induced human skeletal muscle glucose uptake in type 2 diabetes is dependent on age rather than diabetic status.

    Babraj JA, Mustard K, Sutherland C, Towler MC, Chen S, Smith K, Green K, Leese G, Hardie DG, Rennie MJ, Cuthbertson DJ.

    Am J Physiol Endocrinol Metab. 2009 May;296(5):E1042-8. Epub 2009 Feb 3.PMID: 19190259 [PubMed - indexed for MEDLINE]Related articles

    3.

    alpha2 Isoform-specific activation of 5'adenosine monophosphate-activated protein kinase by 5-aminoimidazole-4-carboxamide-1-beta-d-ribonucleoside at a physiological level activates glucose transport and increases glucose transporter 4 in mouse skeletal muscle.

    Nakano M, Hamada T, Hayashi T, Yonemitsu S, Miyamoto L, Toyoda T, Tanaka S, Masuzaki H, Ebihara K, Ogawa Y, Hosoda K, Inoue G, Yoshimasa Y, Otaka A, Fushiki T, Nakao K.

    Metabolism. 2006 Mar;55(3):300-8.PMID: 16483872 [PubMed - indexed for MEDLINE]Related articles

    4.

    Knockout of the alpha2 but not alpha1 5'-AMP-activated protein kinase isoform abolishes 5-aminoimidazole-4-carboxamide-1-beta-4-ribofuranosidebut not contraction-induced glucose uptake in skeletal muscle.

    Jørgensen SB, Viollet B, Andreelli F, Frøsig C, Birk JB, Schjerling P, Vaulont S, Richter EA, Wojtaszewski JF.

    J Biol Chem. 2004 Jan 9;279(2):1070-9. Epub 2003 Oct 21.PMID: 14573616 [PubMed - indexed for MEDLINE]Related articlesFree article

    5.

    Effect of AICAR treatment on glycogen metabolism in skeletal muscle.

    Aschenbach WG, Hirshman MF, Fujii N, Sakamoto K, Howlett KF, Goodyear LJ.

    Diabetes. 2002 Mar;51(3):567-73.PMID: 11872652 [PubMed - indexed for MEDLINE]Related articlesFree article

    6.

    Effect of AMPK activation on muscle glucose metabolism in conscious rats.

    Bergeron R, Russell RR 3rd, Young LH, Ren JM, Marcucci M, Lee A, Shulman GI.

    Am J Physiol. 1999 May;276(5 Pt 1):E938-44.PMID: 10329989 [PubMed - indexed for MEDLINE]Related articlesFree article

    7.

    Effect of acute activation of 5'-AMP-activated protein kinase on glycogen regulation in isolated rat skeletal muscle.

    Miyamoto L, Toyoda T, Hayashi T, Yonemitsu S, Nakano M, Tanaka S, Ebihara K, Masuzaki H, Hosoda K, Ogawa Y, Inoue G, Fushiki T, Nakao K.

    J Appl Physiol. 2007 Mar;102(3):1007-13. Epub 2006 Nov 22.PMID: 17122373 [PubMed - indexed for MEDLINE]Related articlesFree article

    8.

    AMP-activated protein kinase activation by AICAR increases both muscle fatty acid and glucose uptake in white muscle of insulin-resistant rats in vivo.

    Iglesias MA, Furler SM, Cooney GJ, Kraegen EW, Ye JM.

    Diabetes. 2004 Jul;53(7):1649-54.PMID: 15220186 [PubMed - indexed for MEDLINE]Related articlesFree article

    9.

    Prior serum- and AICAR-induced AMPK activation in primary human myocytes does not lead to subsequent increase in insulin-stimulated glucose uptake.

    Al-Khalili L, Krook A, Zierath JR, Cartee GD.

    Am J Physiol Endocrinol Metab. 2004 Sep;287(3):E553-7. Epub 2004 May 18.PMID: 15149951 [PubMed - indexed for MEDLINE]Related articlesFree article

    10.

    Impact of in vivo fatty acid oxidation blockade on glucose turnover and muscle glucose metabolism during low-dose AICAR infusion.

    Christopher M, Rantzau C, Chen ZP, Snow R, Kemp B, Alford FP.

    Am J Physiol Endocrinol Metab. 2006 Nov;291(5):E1131-40. Epub 2006 Jun 13.PMID: 16772328 [PubMed - indexed for MEDLINE]Related articlesFree article

    11.

    Inhibition of insulin-stimulated glycogen synthesis by 5-aminoimidasole-4-carboxamide-1-beta-d-ribofuranoside-induced adenosine 5'-monophosphate-activated protein kinase activation: interactions with Akt, glycogen synthase kinase 3-3alpha/beta, and glycogen synthase in isolated rat soleus muscle.

    Fediuc S, Gaidhu MP, Ceddia RB.

    Endocrinology. 2006 Nov;147(11):5170-7. Epub 2006 Jul 27.PMID: 16873531 [PubMed - indexed for MEDLINE]Related articlesFree article

    12.

    AMPK activation is not critical in the regulation of muscle FA uptake and oxidation during low-intensity muscle contraction.

    Raney MA, Yee AJ, Todd MK, Turcotte LP.

    Am J Physiol Endocrinol Metab. 2005 Mar;288(3):E592-8. Epub 2004 Nov 16.PMID: 15547141 [PubMed - indexed for MEDLINE]Related articlesFree article

    13.

    Effect of 5-aminoimidazole-4-carboxamide-1-beta-D-ribofuranoside infusion on in vivo glucose and lipid metabolism in lean and obese Zucker rats.

    Bergeron R, Previs SF, Cline GW, Perret P, Russell RR 3rd, Young LH, Shulman GI.

    Diabetes. 2001 May;50(5):1076-82.PMID: 11334411 [PubMed - indexed for MEDLINE]Related articlesFree article

    14.

    Intracerebroventricular infusion of glucose, insulin, and the adenosine monophosphate-activated kinase activator, 5-aminoimidazole-4-carboxamide-1-beta-D-ribofuranoside, controls muscle glycogen synthesis.

    Perrin C, Knauf C, Burcelin R.

    Endocrinology. 2004 Sep;145(9):4025-33. Epub 2004 Jun 10.PMID: 15192044 [PubMed - indexed for MEDLINE]Related articlesFree article

    15.

    Insulin stimulation of glucose uptake fails to decrease palmitate oxidation in muscle if AMPK is activated.

    Winder WW, Holmes BF.

    J Appl Physiol. 2000 Dec;89(6):2430-7.PMID: 11090599 [PubMed - indexed for MEDLINE]Related articlesFree article

    16.

    5-Aminoimidazole-4-carboxamide-1-beta-D-ribofuranoside-induced AMP-activated protein kinase phosphorylation inhibits basal and insulin-stimulated glucose uptake, lipid synthesis, and fatty acid oxidation in isolated rat adipocytes.

    Gaidhu MP, Fediuc S, Ceddia RB.

    J Biol Chem. 2006 Sep 8;281(36):25956-64. Epub 2006 Jul 1.PMID: 16816404 [PubMed - indexed for MEDLINE]Related articlesFree article

    17.

    Glycogen-dependent effects of 5-aminoimidazole-4-carboxamide (AICA)-riboside on AMP-activated protein kinase and glycogen synthase activities in rat skeletal muscle.

    Wojtaszewski JF, Jørgensen SB, Hellsten Y, Hardie DG, Richter EA.

    Diabetes. 2002 Feb;51(2):284-92.PMID: 11812734 [PubMed - indexed for MEDLINE]Related articlesFree article

    18.

    AMPK activation with AICAR provokes an acute fall in plasma [K+].

    Zheng D, Perianayagam A, Lee DH, Brannan MD, Yang LE, Tellalian D, Chen P, Lemieux K, Marette A, Youn JH, McDonough AA.

    Am J Physiol Cell Physiol. 2008 Jan;294(1):C126-35. Epub 2007 Nov 14.PMID: 18003746 [PubMed - indexed for MEDLINE]Related articlesFree article

    19.

    The AMP-activated protein kinase activator AICAR does not induce GLUT4 translocation to transverse tubules but stimulates glucose uptake and p38 mitogen-activated protein kinases alpha and beta in skeletal muscle.

    Lemieux K, Konrad D, Klip A, Marette A.

    FASEB J. 2003 Sep;17(12):1658-65.PMID: 12958172 [PubMed - indexed for MEDLINE]Related articlesFree article

    20.

    Activity of LKB1 and AMPK-related kinases in skeletal muscle: effects of contraction, phenformin, and AICAR.

    Sakamoto K, Göransson O, Hardie DG, Alessi DR.

    Am J Physiol Endocrinol Metab. 2004 Aug;287(2):E310-7. Epub 2004 Apr 6.PMID: 15068958 [PubMed - indexed for MEDLINE]Related articlesFree article

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