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Association of the estrogen receptor-alpha gene with the metabolic syndrome and its component traits in African-American families: the Insulin Resistance Atherosclerosis Family Study.

Gallagher CJ, Langefeld CD, Gordon CJ, Campbell JK, Mychaleckyj JC, Bryer-Ash M, Rich SS, Bowden DW, Sale MM.

Diabetes. 2007 Aug;56(8):2135-41. Epub 2007 May 18. Erratum in: Diabetes. 2007 Oct;56(10):2650. Mychalecky, Josyf C [corrected to Mychaleckyj, Josyf C]. PMID: 17513703 [PubMed - indexed for MEDLINE]Related articlesFree article

Metabolic syndrome in nondiabetic, obese, first-degree relatives of African American patients with type 2 diabetes: African American triglycerides-HDL-C and insulin resistance paradox.

Meis SB, Schuster D, Gaillard T, Osei K.

Ethn Dis. 2006 Autumn;16(4):830-6.PMID: 17061734 [PubMed - indexed for MEDLINE]Related articles

Investigation of the estrogen receptor-alpha gene with type 2 diabetes and/or nephropathy in African-American and European-American populations.

Gallagher CJ, Keene KL, Mychaleckyj JC, Langefeld CD, Hirschhorn JN, Henderson BE, Gordon CJ, Freedman BI, Rich SS, Bowden DW, Sale MM.

Diabetes. 2007 Mar;56(3):675-84.PMID: 17327435 [PubMed - indexed for MEDLINE]Related articlesFree article

Quantitative trait analysis of type 2 diabetes susceptibility loci identified from whole genome association studies in the Insulin Resistance Atherosclerosis Family Study.

Palmer ND, Goodarzi MO, Langefeld CD, Ziegler J, Norris JM, Haffner SM, Bryer-Ash M, Bergman RN, Wagenknecht LE, Taylor KD, Rotter JI, Bowden DW.

Diabetes. 2008 Apr;57(4):1093-100. Epub 2008 Feb 5.PMID: 18252897 [PubMed - indexed for MEDLINE]Related articlesFree article

Estrogen receptor alpha gene variants associate with type 2 diabetes and fasting plasma glucose.

Dahlman I, Vaxillaire M, Nilsson M, Lecoeur C, Gu HF, Cavalcanti-Proença C, Efendic S, Ostenson CG, Brismar K, Charpentier G, Gustafsson JA, Froguel P, Dahlman-Wright K, Steffensen KR.

Pharmacogenet Genomics. 2008 Nov;18(11):967-75.PMID: 18854778 [PubMed - indexed for MEDLINE]Related articles

Genetic variants of FTO influence adiposity, insulin sensitivity, leptin levels, and resting metabolic rate in the Quebec Family Study.

Do R, Bailey SD, Desbiens K, Belisle A, Montpetit A, Bouchard C, Pérusse L, Vohl MC, Engert JC.

Diabetes. 2008 Apr;57(4):1147-50. Epub 2008 Mar 3.PMID: 18316358 [PubMed - indexed for MEDLINE]Related articlesFree article

Comprehensive evaluation of the estrogen receptor alpha gene reveals further evidence for association with type 2 diabetes enriched for nephropathy in an African American population.

Keene KL, Mychaleckyj JC, Smith SG, Leak TS, Perlegas PS, Langefeld CD, Herrington DM, Freedman BI, Rich SS, Bowden DW, Sale MM.

Hum Genet. 2008 May;123(4):333-41. Epub 2008 Feb 28.PMID: 18305958 [PubMed - indexed for MEDLINE]Related articlesFree article

The association of genetic polymorphisms in sex hormone biosynthesis and action with insulin sensitivity and diabetes mellitus in women at midlife.

Lo JC, Zhao X, Scuteri A, Brockwell S, Sowers MR.

Am J Med. 2006 Sep;119(9 Suppl 1):S69-78.PMID: 16949391 [PubMed - indexed for MEDLINE]Related articles

Transcription factor 7-like 2 polymorphisms and type 2 diabetes, glucose homeostasis traits and gene expression in US participants of European and African descent.

Elbein SC, Chu WS, Das SK, Yao-Borengasser A, Hasstedt SJ, Wang H, Rasouli N, Kern PA.

Diabetologia. 2007 Aug;50(8):1621-30. Epub 2007 Jun 20.PMID: 17579832 [PubMed - indexed for MEDLINE]Related articles

Association of SSTR2 polymorphisms and glucose homeostasis phenotypes: the Insulin Resistance Atherosclerosis Family Study.

Sutton BS, Palmer ND, Langefeld CD, Xue B, Proctor A, Ziegler JT, Haffner SM, Norris JM, Bowden DW.

Diabetes. 2009 Jun;58(6):1457-62. Epub 2009 Mar 26.PMID: 19324939 [PubMed - indexed for MEDLINE]Related articlesFree article

Polymorphisms near SOCS3 are associated with obesity and glucose homeostasis traits in Hispanic Americans from the Insulin Resistance Atherosclerosis Family Study.

Talbert ME, Langefeld CD, Ziegler J, Mychaleckyj JC, Haffner SM, Norris JM, Bowden DW.

Hum Genet. 2009 Mar;125(2):153-62. Epub 2008 Dec 13.PMID: 19083014 [PubMed - indexed for MEDLINE]Related articles

Analysis of FTO gene variants with measures of obesity and glucose homeostasis in the IRAS Family Study.

Wing MR, Ziegler J, Langefeld CD, Ng MC, Haffner SM, Norris JM, Goodarzi MO, Bowden DW.

Hum Genet. 2009 Jun;125(5-6):615-26. Epub 2009 Mar 26.PMID: 19322589 [PubMed - indexed for MEDLINE]Related articles

Genetic mapping of disposition index and acute insulin response loci on chromosome 11q. The Insulin Resistance Atherosclerosis Study (IRAS) Family Study.

Palmer ND, Langefeld CD, Campbell JK, Williams AH, Saad M, Norris JM, Haffner SM, Rotter JI, Wagenknecht LE, Bergman RN, Rich SS, Bowden DW.

Diabetes. 2006 Apr;55(4):911-8.PMID: 16567510 [PubMed - indexed for MEDLINE]Related articlesFree article

Impact of estrogen receptor gene polymorphisms and mRNA levels on obesity and lipolysis--a cohort study.

Nilsson M, Dahlman I, Jiao H, Gustafsson JA, Arner P, Dahlman-Wright K.

BMC Med Genet. 2007 Dec 4;8:73.PMID: 18053221 [PubMed - indexed for MEDLINE]Related articlesFree article

Variation in IGF2BP2 interacts with adiposity to alter insulin sensitivity in Mexican Americans.

Li X, Allayee H, Xiang AH, Trigo E, Hartiala J, Lawrence JM, Buchanan TA, Watanabe RM.

Obesity (Silver Spring). 2009 Apr;17(4):729-36. Epub 2009 Jan 15.PMID: 19148120 [PubMed - indexed for MEDLINE]Related articles

Association of TCF7L2 gene polymorphisms with reduced acute insulin response in Hispanic Americans.

Palmer ND, Lehtinen AB, Langefeld CD, Campbell JK, Haffner SM, Norris JM, Bergman RN, Goodarzi MO, Rotter JI, Bowden DW.

J Clin Endocrinol Metab. 2008 Jan;93(1):304-9. Epub 2007 Oct 30.PMID: 17971425 [PubMed - indexed for MEDLINE]Related articlesFree article

The uncoupling protein 1 gene, UCP1, is expressed in mammalian islet cells and associated with acute insulin response to glucose in African American families from the IRAS Family Study.

Sale MM, Hsu FC, Palmer ND, Gordon CJ, Keene KL, Borgerink HM, Sharma AJ, Bergman RN, Taylor KD, Saad MF, Norris JM.

BMC Endocr Disord. 2007 Mar 30;7:1.PMID: 17397545 [PubMed]Related articlesFree article

Association of protein tyrosine phosphatase 1B gene polymorphisms with measures of glucose homeostasis in Hispanic Americans: the insulin resistance atherosclerosis study (IRAS) family study.

Palmer ND, Bento JL, Mychaleckyj JC, Langefeld CD, Campbell JK, Norris JM, Haffner SM, Bergman RN, Bowden DW; insulin resistance atherosclerosis study (IRAS) family study.

Diabetes. 2004 Nov;53(11):3013-9.PMID: 15504985 [PubMed - indexed for MEDLINE]Related articlesFree article

A genome-wide association scan for acute insulin response to glucose in Hispanic-Americans: the Insulin Resistance Atherosclerosis Family Study (IRAS FS).

Rich SS, Goodarzi MO, Palmer ND, Langefeld CD, Ziegler J, Haffner SM, Bryer-Ash M, Norris JM, Taylor KD, Haritunians T, Rotter JI, Chen YD, Wagenknecht LE, Bowden DW, Bergman RN.

Diabetologia. 2009 Jul;52(7):1326-33. Epub 2009 May 9.PMID: 19430760 [PubMed - indexed for MEDLINE]Related articles

Protein tyrosine phosphatase-1B gene PTPN1: selection of tagging single nucleotide polymorphisms and association with body fat, insulin sensitivity, and the metabolic syndrome in a normal female population.

Spencer-Jones NJ, Wang X, Snieder H, Spector TD, Carter ND, O'Dell SD.

Diabetes. 2005 Nov;54(11):3296-304.PMID: 16249458 [PubMed - indexed for MEDLINE]Related articlesFree article