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Effects of endurance exercise training on insulin signaling in human skeletal muscle: interactions at the level of phosphatidylinositol 3-kinase, Akt, and AS160.

Frøsig C, Rose AJ, Treebak JT, Kiens B, Richter EA, Wojtaszewski JF.

Diabetes. 2007 Aug;56(8):2093-102. Epub 2007 May 18.PMID: 17513702 [PubMed - indexed for MEDLINE]Related articlesFree article

Caffeine-induced impairment of insulin action but not insulin signaling in human skeletal muscle is reduced by exercise.

Thong FS, Derave W, Kiens B, Graham TE, Ursø B, Wojtaszewski JF, Hansen BF, Richter EA.

Diabetes. 2002 Mar;51(3):583-90.PMID: 11872654 [PubMed - indexed for MEDLINE]Related articlesFree article

Insulin-stimulated insulin receptor substrate-2-associated phosphatidylinositol 3-kinase activity is enhanced in human skeletal muscle after exercise.

Howlett KF, Sakamoto K, Yu H, Goodyear LJ, Hargreaves M.

Metabolism. 2006 Aug;55(8):1046-52.PMID: 16839840 [PubMed - indexed for MEDLINE]Related articles

The effect of exercise and insulin on AS160 phosphorylation and 14-3-3 binding capacity in human skeletal muscle.

Howlett KF, Mathews A, Garnham A, Sakamoto K.

Am J Physiol Endocrinol Metab. 2008 Feb;294(2):E401-7. Epub 2007 Nov 27.PMID: 18042670 [PubMed - indexed for MEDLINE]Related articlesFree article

Effects of exercise and insulin on insulin signaling proteins in human skeletal muscle.

Koval JA, Maezono K, Patti ME, Pendergrass M, DeFronzo RA, Mandarino LJ.

Med Sci Sports Exerc. 1999 Jul;31(7):998-1004.PMID: 10416561 [PubMed - indexed for MEDLINE]Related articles

Insulin signaling in human skeletal muscle: time course and effect of exercise.

Wojtaszewski JF, Hansen BF, Kiens B, Richter EA.

Diabetes. 1997 Nov;46(11):1775-81.PMID: 9356025 [PubMed - indexed for MEDLINE]Related articles

Exercise-induced changes in expression and activity of proteins involved in insulin signal transduction in skeletal muscle: differential effects on insulin-receptor substrates 1 and 2.

Chibalin AV, Yu M, Ryder JW, Song XM, Galuska D, Krook A, Wallberg-Henriksson H, Zierath JR.

Proc Natl Acad Sci U S A. 2000 Jan 4;97(1):38-43.PMID: 10618367 [PubMed - indexed for MEDLINE]Related articlesFree article

Insulin signaling and insulin sensitivity after exercise in human skeletal muscle.

Wojtaszewski JF, Hansen BF, Gade, Kiens B, Markuns JF, Goodyear LJ, Richter EA.

Diabetes. 2000 Mar;49(3):325-31.PMID: 10868952 [PubMed - indexed for MEDLINE]Related articlesFree article

Endurance training improves responsiveness to insulin and modulates insulin signal transduction through the phosphatidylinositol 3-kinase/Akt-1 pathway.

Luciano E, Carneiro EM, Carvalho CR, Carvalheira JB, Peres SB, Reis MA, Saad MJ, Boschero AC, Velloso LA.

Eur J Endocrinol. 2002 Jul;147(1):149-57.PMID: 12088932 [PubMed - indexed for MEDLINE]Related articlesFree article

Exercise improves phosphatidylinositol-3,4,5-trisphosphate responsiveness of atypical protein kinase C and interacts with insulin signalling to peptide elongation in human skeletal muscle.

Frøsig C, Sajan MP, Maarbjerg SJ, Brandt N, Roepstorff C, Wojtaszewski JF, Kiens B, Farese RV, Richter EA.

J Physiol. 2007 Aug 1;582(Pt 3):1289-301. Epub 2007 May 31.PMID: 17540697 [PubMed - indexed for MEDLINE]Related articlesFree article

Evidence against a role for insulin-signaling proteins PI 3-kinase and Akt in insulin resistance in human skeletal muscle induced by short-term GH infusion.

Jessen N, Djurhuus CB, Jørgensen JO, Jensen LS, Møller N, Lund S, Schmitz O.

Am J Physiol Endocrinol Metab. 2005 Jan;288(1):E194-9. Epub 2004 Aug 31.PMID: 15339744 [PubMed - indexed for MEDLINE]Related articlesFree article

Role of Akt2 in contraction-stimulated cell signaling and glucose uptake in skeletal muscle.

Sakamoto K, Arnolds DE, Fujii N, Kramer HF, Hirshman MF, Goodyear LJ.

Am J Physiol Endocrinol Metab. 2006 Nov;291(5):E1031-7. Epub 2006 Jun 27.PMID: 16803855 [PubMed - indexed for MEDLINE]Related articlesFree article

Regular exercise enhances insulin activation of IRS-1-associated PI3-kinase in human skeletal muscle.

Kirwan JP, del Aguila LF, Hernandez JM, Williamson DL, O'Gorman DJ, Lewis R, Krishnan RK.

J Appl Physiol. 2000 Feb;88(2):797-803.PMID: 10658053 [PubMed - indexed for MEDLINE]Related articlesFree article

Potential role of TBC1D4 in enhanced post-exercise insulin action in human skeletal muscle.

Treebak JT, Frøsig C, Pehmøller C, Chen S, Maarbjerg SJ, Brandt N, MacKintosh C, Zierath JR, Hardie DG, Kiens B, Richter EA, Pilegaard H, Wojtaszewski JF.

Diabetologia. 2009 May;52(5):891-900. Epub 2009 Feb 28.PMID: 19252894 [PubMed - indexed for MEDLINE]Related articles

Increased insulin-stimulated Akt pSer473 and cytosolic SHP2 protein abundance in human skeletal muscle following acute exercise and short-term training.

Wadley GD, Konstantopoulos N, Macaulay L, Howlett KF, Garnham A, Hargreaves M, Cameron-Smith D.

J Appl Physiol. 2007 Apr;102(4):1624-31. Epub 2006 Dec 21.PMID: 17185494 [PubMed - indexed for MEDLINE]Related articlesFree article

Exercise training increases glycogen synthase activity and GLUT4 expression but not insulin signaling in overweight nondiabetic and type 2 diabetic subjects.

Christ-Roberts CY, Pratipanawatr T, Pratipanawatr W, Berria R, Belfort R, Kashyap S, Mandarino LJ.

Metabolism. 2004 Sep;53(9):1233-42.PMID: 15334390 [PubMed - indexed for MEDLINE]Related articles

Reduced malonyl-CoA content in recovery from exercise correlates with improved insulin-stimulated glucose uptake in human skeletal muscle.

Frøsig C, Roepstorff C, Brandt N, Maarbjerg SJ, Birk JB, Wojtaszewski JF, Richter EA, Kiens B.

Am J Physiol Endocrinol Metab. 2009 Apr;296(4):E787-95. Epub 2009 Feb 3.PMID: 19190265 [PubMed - indexed for MEDLINE]Related articles

Role of Akt substrate of 160 kDa in insulin-stimulated and contraction-stimulated glucose transport.

Cartee GD, Wojtaszewski JF.

Appl Physiol Nutr Metab. 2007 Jun;32(3):557-66. Review.PMID: 17510697 [PubMed - indexed for MEDLINE]Related articles

Altered PI3-kinase/Akt signalling in skeletal muscle of young men with low birth weight.

Jensen CB, Martin-Gronert MS, Storgaard H, Madsbad S, Vaag A, Ozanne SE.

PLoS One. 2008;3(11):e3738. Epub 2008 Nov 17.PMID: 19011679 [PubMed - indexed for MEDLINE]Related articlesFree article

Muscle damage impairs insulin stimulation of IRS-1, PI 3-kinase, and Akt-kinase in human skeletal muscle.

Del Aguila LF, Krishnan RK, Ulbrecht JS, Farrell PA, Correll PH, Lang CH, Zierath JR, Kirwan JP.

Am J Physiol Endocrinol Metab. 2000 Jul;279(1):E206-12.PMID: 10893341 [PubMed - indexed for MEDLINE]Related articlesFree article