PubMed

Reduced incretin effect in type 2 diabetes: cause or consequence of the diabetic state?

Knop FK, Vilsbøll T, Højberg PV, Larsen S, Madsbad S, Vølund A, Holst JJ, Krarup T.

Diabetes. 2007 Aug;56(8):1951-9. Epub 2007 May 18.PMID: 17513701 [PubMed - indexed for MEDLINE]Related articlesFree article

Separate impact of obesity and glucose tolerance on the incretin effect in normal subjects and type 2 diabetic patients.

Muscelli E, Mari A, Casolaro A, Camastra S, Seghieri G, Gastaldelli A, Holst JJ, Ferrannini E.

Diabetes. 2008 May;57(5):1340-8. Epub 2007 Dec 27.PMID: 18162504 [PubMed - indexed for MEDLINE]Related articlesFree article

Incretin secretion in relation to meal size and body weight in healthy subjects and people with type 1 and type 2 diabetes mellitus.

Vilsbøll T, Krarup T, Sonne J, Madsbad S, Vølund A, Juul AG, Holst JJ.

J Clin Endocrinol Metab. 2003 Jun;88(6):2706-13.PMID: 12788877 [PubMed - indexed for MEDLINE]Related articlesFree article

The pathophysiology of diabetes involves a defective amplification of the late-phase insulin response to glucose by glucose-dependent insulinotropic polypeptide-regardless of etiology and phenotype.

Vilsbøll T, Knop FK, Krarup T, Johansen A, Madsbad S, Larsen S, Hansen T, Pedersen O, Holst JJ.

J Clin Endocrinol Metab. 2003 Oct;88(10):4897-903.PMID: 14557471 [PubMed - indexed for MEDLINE]Related articlesFree article

Secretion of incretin hormones (GIP and GLP-1) and incretin effect after oral glucose in first-degree relatives of patients with type 2 diabetes.

Nauck MA, El-Ouaghlidi A, Gabrys B, Hücking K, Holst JJ, Deacon CF, Gallwitz B, Schmidt WE, Meier JJ.

Regul Pept. 2004 Nov 15;122(3):209-17.PMID: 15491793 [PubMed - indexed for MEDLINE]Related articles

The insulinotropic effect of GIP is impaired in patients with chronic pancreatitis and secondary diabetes mellitus as compared to patients with chronic pancreatitis and normal glucose tolerance.

Knop FK, Vilsbøll T, Højberg PV, Larsen S, Madsbad S, Holst JJ, Krarup T.

Regul Pept. 2007 Dec 4;144(1-3):123-30. Epub 2007 Jul 13.PMID: 17692937 [PubMed - indexed for MEDLINE]Related articles

Inappropriate suppression of glucagon during OGTT but not during isoglycaemic i.v. glucose infusion contributes to the reduced incretin effect in type 2 diabetes mellitus.

Knop FK, Vilsbøll T, Madsbad S, Holst JJ, Krarup T.

Diabetologia. 2007 Apr;50(4):797-805. Epub 2007 Jan 16.PMID: 17225124 [PubMed - indexed for MEDLINE]Related articles

No hypoglycemia after subcutaneous administration of glucagon-like peptide-1 in lean type 2 diabetic patients and in patients with diabetes secondary to chronic pancreatitis.

Knop FK, Vilsbøll T, Larsen S, Madsbad S, Holst JJ, Krarup T.

Diabetes Care. 2003 Sep;26(9):2581-7.PMID: 12941722 [PubMed - indexed for MEDLINE]Related articlesFree article

Reduced incretin effect in type 2 (non-insulin-dependent) diabetes.

Nauck M, Stöckmann F, Ebert R, Creutzfeldt W.

Diabetologia. 1986 Jan;29(1):46-52.PMID: 3514343 [PubMed - indexed for MEDLINE]Related articles

Determinants of the impaired secretion of glucagon-like peptide-1 in type 2 diabetic patients.

Toft-Nielsen MB, Damholt MB, Madsbad S, Hilsted LM, Hughes TE, Michelsen BK, Holst JJ.

J Clin Endocrinol Metab. 2001 Aug;86(8):3717-23.PMID: 11502801 [PubMed - indexed for MEDLINE]Related articlesFree article

Normal secretion of the incretin hormones glucose-dependent insulinotropic polypeptide and glucagon-like peptide-1 during gestational diabetes mellitus.

Cypryk K, Vilsbøll T, Nadel I, Smyczyńska J, Holst JJ, Lewiński A.

Gynecol Endocrinol. 2007 Jan;23(1):58-62.PMID: 17484514 [PubMed - indexed for MEDLINE]Related articles

Predictors of incretin concentrations in subjects with normal, impaired, and diabetic glucose tolerance.

Vollmer K, Holst JJ, Baller B, Ellrichmann M, Nauck MA, Schmidt WE, Meier JJ.

Diabetes. 2008 Mar;57(3):678-87. Epub 2007 Dec 5.PMID: 18057091 [PubMed - indexed for MEDLINE]Related articlesFree article

Preserved incretin effect in type 1 diabetic patients with end-stage nephropathy treated by combined heterotopic pancreas and kidney transplantation.

Nauck MA, Büsing M, Orskov C, Siegel EG, Talartschik J, Baartz A, Baartz T, Hopt UT, Becker HD, Creutzfeldt W.

Acta Diabetol. 1993;30(1):39-45.PMID: 8329730 [PubMed - indexed for MEDLINE]Related articles

Impact of incretin hormones on beta-cell function in subjects with normal or impaired glucose tolerance.

Muscelli E, Mari A, Natali A, Astiarraga BD, Camastra S, Frascerra S, Holst JJ, Ferrannini E.

Am J Physiol Endocrinol Metab. 2006 Dec;291(6):E1144-50. Epub 2006 Feb 14.PMID: 16478775 [PubMed - indexed for MEDLINE]Related articlesFree article

The impact of diabetic autonomic neuropathy on the incretin effect.

Kazakos KA, Sarafidis PA, Yovos JG.

Med Sci Monit. 2008 Apr;14(4):CR213-20.PMID: 18376350 [PubMed - indexed for MEDLINE]Related articlesFree article

Plasma dipeptidyl peptidase-IV activity in patients with type-2 diabetes mellitus correlates positively with HbAlc levels, but is not acutely affected by food intake.

Ryskjaer J, Deacon CF, Carr RD, Krarup T, Madsbad S, Holst J, Vilsbøll T.

Eur J Endocrinol. 2006 Sep;155(3):485-93.PMID: 16914604 [PubMed - indexed for MEDLINE]Related articlesFree article

Similar insulin secretory response to a gastric inhibitory polypeptide bolus injection at euglycemia in first-degree relatives of patients with type 2 diabetes and control subjects.

Meier JJ, Nauck MA, Siepmann N, Greulich M, Holst JJ, Deacon CF, Schmidt WE, Gallwitz B.

Metabolism. 2003 Dec;52(12):1579-85.PMID: 14669159 [PubMed - indexed for MEDLINE]Related articles

[Evaluation of islet beta cell function in subjects with normal glucose tolerance, impaired glucose regulation, and type 2 diabetes mellitus]

Liu J, Li YB, Shao H, Li YX, Yuan YH, Xiao YB, Weng JP.

Zhonghua Yi Xue Za Zhi. 2007 May 15;87(18):1252-5. Chinese. PMID: 17686259 [PubMed - indexed for MEDLINE]Related articles

Increased postprandial responses of GLP-1 and GIP in patients with chronic pancreatitis and steatorrhea following pancreatic enzyme substitution.

Knop FK, Vilsbøll T, Larsen S, Højberg PV, Vølund A, Madsbad S, Holst JJ, Krarup T.

Am J Physiol Endocrinol Metab. 2007 Jan;292(1):E324-30. Epub 2006 Sep 5.PMID: 16954337 [PubMed - indexed for MEDLINE]Related articlesFree article

Human duodenal enteroendocrine cells: source of both incretin peptides, GLP-1 and GIP.

Theodorakis MJ, Carlson O, Michopoulos S, Doyle ME, Juhaszova M, Petraki K, Egan JM.

Am J Physiol Endocrinol Metab. 2006 Mar;290(3):E550-9. Epub 2005 Oct 11.PMID: 16219666 [PubMed - indexed for MEDLINE]Related articlesFree article