Warning: The NCBI web site requires JavaScript to function. more...
Efficient inhibition of HIV-1 expression by LNA modified antisense oligonucleotides and DNAzymes targeted to functionally selected binding sites.
Jakobsen MR, Haasnoot J, Wengel J, Berkhout B, Kjems J.
Retrovirology. 2007 Apr 26;4:29.
Related citations
A genomic selection strategy to identify accessible and dimerization blocking targets in the 5'-UTR of HIV-1 RNA.
Jakobsen MR, Damgaard CK, Andersen ES, Podhajska A, Kjems J.
Nucleic Acids Res. 2004 Apr 23;32(7):e67.
A structure-activity study of the inhibition of HIV-1 Tat-dependent trans-activation by mixmer 2'-O-methyl oligoribonucleotides containing locked nucleic acid (LNA), alpha-L-LNA, or 2'-thio-LNA residues.
Arzumanov A, Stetsenko DA, Malakhov AD, Reichelt S, Sørensen MD, Babu BR, Wengel J, Gait MJ.
Oligonucleotides. 2003;13(6):435-53.
Specific inhibition of in vitro reverse transcription using antisense oligonucleotides targeted to the TAR regions of HIV-1 and HIV-2.
Boulme F, Perälä-Heape M, Sarih-Cottin L, Litvak S.
Biochim Biophys Acta. 1997 Apr 10;1351(3):249-55.
In vitro effect of antisense oligonucleotides on human immunodeficiency virus type 1 reverse transcription.
Bordier B, Hélène C, Barr PJ, Litvak S, Sarih-Cottin L.
Nucleic Acids Res. 1992 Nov 25;20(22):5999-6006.
Locked nucleic acid containing antisense oligonucleotides enhance inhibition of HIV-1 genome dimerization and inhibit virus replication.
Elmén J, Zhang HY, Zuber B, Ljungberg K, Wahren B, Wahlestedt C, Liang Z.
FEBS Lett. 2004 Dec 17;578(3):285-90.
Antisense inhibition of gene expression in cells by oligonucleotides incorporating locked nucleic acids: effect of mRNA target sequence and chimera design.
Braasch DA, Liu Y, Corey DR.
Nucleic Acids Res. 2002 Dec 1;30(23):5160-7.
Tricyclo-DNA containing oligonucleotides as steric block inhibitors of human immunodeficiency virus type 1 tat-dependent trans-activation and HIV-1 infectivity.
Ivanova G, Reigadas S, Ittig D, Arzumanov A, Andreola ML, Leumann C, Toulmé JJ, Gait MJ.
Oligonucleotides. 2007 Spring;17(1):54-65.
Locked nucleoside analogues expand the potential of DNAzymes to cleave structured RNA targets.
Vester B, Hansen LH, Lundberg LB, Babu BR, Sørensen MD, Wengel J, Douthwaite S.
BMC Mol Biol. 2006 Jun 5;7:19.
In vitro and in vivo transport and delivery of phosphorothioate oligonucleotides with cationic liposomes.
Miyano-Kurosaki N, Barnor JS, Takeuchi H, Owada T, Nakashima H, Yamamoto N, Matsuzaki T, Shimada F, Takaku H.
Antivir Chem Chemother. 2004 Mar;15(2):93-100.
The multiple inhibitory mechanisms of GEM 91, a gag antisense phosphorothioate oligonucleotide, for human immunodeficiency virus type 1.
Yamaguchi K, Papp B, Zhang D, Ali AN, Agrawal S, Byrn RA.
AIDS Res Hum Retroviruses. 1997 May 1;13(7):545-54.
Mechanisms of inhibition of in vitro dimerization of HIV type I RNA by sense and antisense oligonucleotides.
Skripkin E, Paillart JC, Marquet R, Blumenfeld M, Ehresmann B, Ehresmann C.
J Biol Chem. 1996 Nov 15;271(46):28812-7.
Antiviral activity of steric-block oligonucleotides targeting the HIV-1 trans-activation response and packaging signal stem-loop RNAs.
Brown D, Arzumanov AA, Turner JJ, Stetsenko DA, Lever AM, Gait MJ.
Nucleosides Nucleotides Nucleic Acids. 2005;24(5-7):393-6.
Hairpin antisense oligonucleotides containing 2'-methoxynucleosides with base-pairing in the stem region at the 3'-end: penetration, localization, and Anti-HIV activity.
Kuwasaki T, Hosono K, Takai K, Ushijima K, Nakashima H, Saito T, Yamamoto N, Takaku H.
Biochem Biophys Res Commun. 1996 Nov 12;228(2):623-31.
Study of HIV-2 primer-template initiation complex using antisense oligonucleotides.
Boulmé F, Freund F, Gryaznov S, Nielsen PE, Tarrago-Litvak L, Litvak S.
Eur J Biochem. 2000 May;267(9):2803-11.
Inhibition of HIV-1 replication by triple-helix-forming phosphorothioate oligonucleotides targeted to the polypurine tract.
Tsukahara S, Suzuki J, Hiratou T, Takai K, Koyanagi Y, Yamamoto N, Takaku H.
Biochem Biophys Res Commun. 1997 Apr 28;233(3):742-7.
In vitro evidence that the untranslated leader of the HIV-1 genome is an RNA checkpoint that regulates multiple functions through conformational changes.
Berkhout B, Ooms M, Beerens N, Huthoff H, Southern E, Verhoef K.
J Biol Chem. 2002 May 31;277(22):19967-75. Epub 2002 Mar 14.
Inhibition of HIV-1 replication and dimerization interference by dual inhibitory RNAs.
Sánchez-Luque FJ, Reyes-Darias JA, Puerta-Fernández E, Berzal-Herranz A.
Molecules. 2010 Jul 7;15(7):4757-72.
Antisense oligonucleotides inhibit in vitro cDNA synthesis by HIV-1 reverse transcriptase.
Boiziau C, Tarrago-Litvak L, Sinha ND, Moreau S, Litvak S, Toulmé JJ.
Antisense Nucleic Acid Drug Dev. 1996 Summer;6(2):103-9.
Inhibition of papilloma progression by antisense oligonucleotides targeted to HPV11 E6/E7 RNA.
Clawson GA, Miranda GQ, Sivarajah A, Xin P, Pan W, Thiboutot D, Christensen ND.
Gene Ther. 2004 Sep;11(17):1331-41.
Filter your results:
Your browsing activity is empty.
Activity recording is turned off.
Turn recording back on