PubMed

Adipose mitochondrial biogenesis is suppressed in db/db and high-fat diet-fed mice and improved by rosiglitazone.

Rong JX, Qiu Y, Hansen MK, Zhu L, Zhang V, Xie M, Okamoto Y, Mattie MD, Higashiyama H, Asano S, Strum JC, Ryan TE.

Diabetes. 2007 Jul;56(7):1751-60. Epub 2007 Apr 24.PMID: 17456854 [PubMed - indexed for MEDLINE]Related articlesFree article

Effect of rosiglitazone on peroxisome proliferator-activated receptor gamma gene expression in human adipose tissue is limited by antiretroviral drug-induced mitochondrial dysfunction.

Mallon PW, Sedwell R, Rogers G, Nolan D, Unemori P, Hoy J, Samaras K, Kelleher A, Emery S, Cooper DA, Carr A; Rosey Investigators.

J Infect Dis. 2008 Dec 15;198(12):1794-803.PMID: 18954260 [PubMed - indexed for MEDLINE]Related articles

Up-regulation of peroxisome proliferator-activated receptors (PPAR-alpha) and PPAR-gamma messenger ribonucleic acid expression in the liver in murine obesity: troglitazone induces expression of PPAR-gamma-responsive adipose tissue-specific genes in the liver of obese diabetic mice.

Memon RA, Tecott LH, Nonogaki K, Beigneux A, Moser AH, Grunfeld C, Feingold KR.

Endocrinology. 2000 Nov;141(11):4021-31.PMID: 11089532 [PubMed - indexed for MEDLINE]Related articlesFree article

Effects of PPARgamma and PPARalpha agonists on serum leptin levels in diet-induced obese rats.

Törüner F, Akbay E, Cakir N, Sancak B, Elbeg S, Taneri F, Aktürk M, Karakoç A, Ayvaz G, Arslan M.

Horm Metab Res. 2004 Apr;36(4):226-30.PMID: 15114521 [PubMed - indexed for MEDLINE]Related articles

Comparison of mitochondrial and macrophage content between subcutaneous and visceral fat in db/db mice.

Okamoto Y, Higashiyama H, Rong JX, McVey MJ, Kinoshita M, Asano S, Hansen MK.

Exp Mol Pathol. 2007 Aug;83(1):73-83. Epub 2007 Mar 12.PMID: 17434481 [PubMed - indexed for MEDLINE]Related articles

Peroxisome proliferator activator receptor gamma coactivator-1 expression is reduced in obesity: potential pathogenic role of saturated fatty acids and p38 mitogen-activated protein kinase activation.

Crunkhorn S, Dearie F, Mantzoros C, Gami H, da Silva WS, Espinoza D, Faucette R, Barry K, Bianco AC, Patti ME.

J Biol Chem. 2007 May 25;282(21):15439-50. Epub 2007 Apr 6.PMID: 17416903 [PubMed - indexed for MEDLINE]Related articlesFree article

Adiponectin mediates the suppressive effect of rosiglitazone on plasminogen activator inhibitor-1 production.

Hoo RL, Chow WS, Yau MH, Xu A, Tso AW, Tse HF, Fong CH, Tam S, Chan L, Lam KS.

Arterioscler Thromb Vasc Biol. 2007 Dec;27(12):2777-82. Epub 2007 Oct 11.PMID: 17932317 [PubMed - indexed for MEDLINE]Related articlesFree article

A novel selective peroxisome proliferator-activator receptor-gamma modulator-SPPARgammaM5 improves insulin sensitivity with diminished adverse cardiovascular effects.

Chang CH, McNamara LA, Wu MS, Muise ES, Tan Y, Wood HB, Meinke PT, Thompson JR, Doebber TW, Berger JP, McCann ME.

Eur J Pharmacol. 2008 Apr 14;584(1):192-201. Epub 2008 Feb 14.PMID: 18346728 [PubMed - indexed for MEDLINE]Related articles

Metallothionein prevents high-fat diet induced cardiac contractile dysfunction: role of peroxisome proliferator activated receptor gamma coactivator 1alpha and mitochondrial biogenesis.

Dong F, Li Q, Sreejayan N, Nunn JM, Ren J.

Diabetes. 2007 Sep;56(9):2201-12. Epub 2007 Jun 15.PMID: 17575086 [PubMed - indexed for MEDLINE]Related articlesFree article

Combined effects of rosiglitazone and conjugated linoleic acid on adiposity, insulin sensitivity, and hepatic steatosis in high-fat-fed mice.

Liu LF, Purushotham A, Wendel AA, Belury MA.

Am J Physiol Gastrointest Liver Physiol. 2007 Jun;292(6):G1671-82. Epub 2007 Feb 22.PMID: 17322064 [PubMed - indexed for MEDLINE]Related articlesFree article

Differential effects of YM440 a hypoglycemic agent on binding to a peroxisome proliferator-activated receptor gamma and its transactivation.

Kurosaki E, Nakano R, Shimaya A, Yoshida S, Ida M, Suzuki T, Shibasaki M, Shikama H.

Biochem Pharmacol. 2003 Mar 1;65(5):795-805.PMID: 12628477 [PubMed - indexed for MEDLINE]Related articles

Acquirement of brown fat cell features by human white adipocytes.

Tiraby C, Tavernier G, Lefort C, Larrouy D, Bouillaud F, Ricquier D, Langin D.

J Biol Chem. 2003 Aug 29;278(35):33370-6. Epub 2003 Jun 13.PMID: 12807871 [PubMed - indexed for MEDLINE]Related articlesFree article

Blood glucose-lowering nuclear receptor agonists only partially normalize hepatic gene expression in db/db mice.

Loffler M, Bilban M, Reimers M, Waldhäusl W, Stulnig TM.

J Pharmacol Exp Ther. 2006 Feb;316(2):797-804. Epub 2005 Oct 31.PMID: 16260581 [PubMed - indexed for MEDLINE]Related articlesFree article

Pioglitazone induces mitochondrial biogenesis in human subcutaneous adipose tissue in vivo.

Bogacka I, Xie H, Bray GA, Smith SR.

Diabetes. 2005 May;54(5):1392-9.PMID: 15855325 [PubMed - indexed for MEDLINE]Related articlesFree article

Polyunsaturated fatty acids of marine origin upregulate mitochondrial biogenesis and induce beta-oxidation in white fat.

Flachs P, Horakova O, Brauner P, Rossmeisl M, Pecina P, Franssen-van Hal N, Ruzickova J, Sponarova J, Drahota Z, Vlcek C, Keijer J, Houstek J, Kopecky J.

Diabetologia. 2005 Nov;48(11):2365-75. Epub 2005 Oct 5.PMID: 16205884 [PubMed - indexed for MEDLINE]Related articles

Peroxisome proliferator-activated receptor-gamma agonist rosiglitazone reverses the adverse effects of diet-induced obesity on oocyte quality.

Minge CE, Bennett BD, Norman RJ, Robker RL.

Endocrinology. 2008 May;149(5):2646-56. Epub 2008 Feb 14.PMID: 18276752 [PubMed - indexed for MEDLINE]Related articlesFree article

Thiazolidinediones and rexinoids induce peroxisome proliferator-activated receptor-coactivator (PGC)-1alpha gene transcription: an autoregulatory loop controls PGC-1alpha expression in adipocytes via peroxisome proliferator-activated receptor-gamma coactivation.

Hondares E, Mora O, Yubero P, Rodriguez de la Concepción M, Iglesias R, Giralt M, Villarroya F.

Endocrinology. 2006 Jun;147(6):2829-38. Epub 2006 Mar 2.PMID: 16513826 [PubMed - indexed for MEDLINE]Related articlesFree article

Cilostazol ameliorates metabolic abnormalities with suppression of proinflammatory markers in a db/db mouse model of type 2 diabetes via activation of peroxisome proliferator-activated receptor gamma transcription.

Park SY, Shin HK, Lee JH, Kim CD, Lee WS, Rhim BY, Hong KW.

J Pharmacol Exp Ther. 2009 May;329(2):571-9. Epub 2009 Feb 12.PMID: 19221061 [PubMed - indexed for MEDLINE]Related articles

Quantitative image analysis in adipose tissue using an automated image analysis system: differential effects of peroxisome proliferator-activated receptor-alpha and -gamma agonist on white and brown adipose tissue morphology in AKR obese and db/db diabetic mice.

Okamoto Y, Higashiyama H, Inoue H, Kanematsu M, Kinoshita M, Asano S.

Pathol Int. 2007 Jun;57(6):369-77.PMID: 17539968 [PubMed - indexed for MEDLINE]Related articles

The PPARgamma ligand, rosiglitazone, reduces vascular oxidative stress and NADPH oxidase expression in diabetic mice.

Hwang J, Kleinhenz DJ, Rupnow HL, Campbell AG, Thulé PM, Sutliff RL, Hart CM.

Vascul Pharmacol. 2007 Jun;46(6):456-62. Epub 2007 Feb 8.PMID: 17337254 [PubMed - indexed for MEDLINE]Related articles