PubMed

Metabolic endotoxemia initiates obesity and insulin resistance.

Cani PD, Amar J, Iglesias MA, Poggi M, Knauf C, Bastelica D, Neyrinck AM, Fava F, Tuohy KM, Chabo C, Waget A, Delmée E, Cousin B, Sulpice T, Chamontin B, Ferrières J, Tanti JF, Gibson GR, Casteilla L, Delzenne NM, Alessi MC, Burcelin R.

Diabetes. 2007 Jul;56(7):1761-72. Epub 2007 Apr 24.PMID: 17456850 [PubMed - indexed for MEDLINE]Related articlesFree article

Changes in gut microbiota control metabolic endotoxemia-induced inflammation in high-fat diet-induced obesity and diabetes in mice.

Cani PD, Bibiloni R, Knauf C, Waget A, Neyrinck AM, Delzenne NM, Burcelin R.

Diabetes. 2008 Jun;57(6):1470-81. Epub 2008 Feb 27.PMID: 18305141 [PubMed - indexed for MEDLINE]Related articlesFree article

Selective increases of bifidobacteria in gut microflora improve high-fat-diet-induced diabetes in mice through a mechanism associated with endotoxaemia.

Cani PD, Neyrinck AM, Fava F, Knauf C, Burcelin RG, Tuohy KM, Gibson GR, Delzenne NM.

Diabetologia. 2007 Nov;50(11):2374-83. Epub 2007 Sep 6.PMID: 17823788 [PubMed - indexed for MEDLINE]Related articles

Energy intake is associated with endotoxemia in apparently healthy men.

Amar J, Burcelin R, Ruidavets JB, Cani PD, Fauvel J, Alessi MC, Chamontin B, Ferriéres J.

Am J Clin Nutr. 2008 May;87(5):1219-23.PMID: 18469242 [PubMed - indexed for MEDLINE]Related articlesFree article

Toll-like receptor-4 mediates vascular inflammation and insulin resistance in diet-induced obesity.

Kim F, Pham M, Luttrell I, Bannerman DD, Tupper J, Thaler J, Hawn TR, Raines EW, Schwartz MW.

Circ Res. 2007 Jun 8;100(11):1589-96. Epub 2007 May 3.PMID: 17478729 [PubMed - indexed for MEDLINE]Related articlesFree article

The role of the gut microbiota in energy metabolism and metabolic disease.

Cani PD, Delzenne NM.

Curr Pharm Des. 2009;15(13):1546-58. Review.PMID: 19442172 [PubMed - indexed for MEDLINE]Related articles

GIP receptor antagonism reverses obesity, insulin resistance, and associated metabolic disturbances induced in mice by prolonged consumption of high-fat diet.

McClean PL, Irwin N, Cassidy RS, Holst JJ, Gault VA, Flatt PR.

Am J Physiol Endocrinol Metab. 2007 Dec;293(6):E1746-55. Epub 2007 Sep 11.PMID: 17848629 [PubMed - indexed for MEDLINE]Related articlesFree article

Chemical gastric inhibitory polypeptide receptor antagonism protects against obesity, insulin resistance, glucose intolerance and associated disturbances in mice fed high-fat and cafeteria diets.

Gault VA, McClean PL, Cassidy RS, Irwin N, Flatt PR.

Diabetologia. 2007 Aug;50(8):1752-62. Epub 2007 Jun 9.PMID: 17558485 [PubMed - indexed for MEDLINE]Related articles

Apolipoprotein E predisposes to obesity and related metabolic dysfunctions in mice.

Karagiannides I, Abdou R, Tzortzopoulou A, Voshol PJ, Kypreos KE.

FEBS J. 2008 Oct;275(19):4796-809. Epub 2008 Aug 27.PMID: 18754772 [PubMed - indexed for MEDLINE]Related articles

Dissociation of obesity and insulin resistance in transgenic mice with skeletal muscle expression of uncoupling protein 1.

Katterle Y, Keipert S, Hof J, Klaus S.

Physiol Genomics. 2008 Feb 19;32(3):352-9. Epub 2007 Nov 27.PMID: 18042832 [PubMed - indexed for MEDLINE]Related articlesFree article

Osteopontin mediates obesity-induced adipose tissue macrophage infiltration and insulin resistance in mice.

Nomiyama T, Perez-Tilve D, Ogawa D, Gizard F, Zhao Y, Heywood EB, Jones KL, Kawamori R, Cassis LA, Tschöp MH, Bruemmer D.

J Clin Invest. 2007 Oct;117(10):2877-88.PMID: 17823662 [PubMed - indexed for MEDLINE]Related articlesFree article

FGFR4 prevents hyperlipidemia and insulin resistance but underlies high-fat diet induced fatty liver.

Huang X, Yang C, Luo Y, Jin C, Wang F, McKeehan WL.

Diabetes. 2007 Oct;56(10):2501-10. Epub 2007 Jul 30.PMID: 17664243 [PubMed - indexed for MEDLINE]Related articlesFree article

Increased oxidative stress precedes the onset of high-fat diet-induced insulin resistance and obesity.

Matsuzawa-Nagata N, Takamura T, Ando H, Nakamura S, Kurita S, Misu H, Ota T, Yokoyama M, Honda M, Miyamoto K, Kaneko S.

Metabolism. 2008 Aug;57(8):1071-7.PMID: 18640384 [PubMed - indexed for MEDLINE]Related articles

Role of gut microflora in the development of obesity and insulin resistance following high-fat diet feeding.

Cani PD, Delzenne NM, Amar J, Burcelin R.

Pathol Biol (Paris). 2008 Jul;56(5):305-9. Epub 2008 Jan 30. Review.PMID: 18178333 [PubMed - indexed for MEDLINE]Related articles

Changes in adiponectin and inflammatory genes in response to hormonal imbalances in female mice and exacerbation of depot selective visceral adiposity by high-fat diet: implications for insulin resistance.

Zhang H, Chen X, Aravindakshan J, Sairam MR.

Endocrinology. 2007 Dec;148(12):5667-79. Epub 2007 Aug 23.PMID: 17717050 [PubMed - indexed for MEDLINE]Related articlesFree article

Loss-of-function mutation in Toll-like receptor 4 prevents diet-induced obesity and insulin resistance.

Tsukumo DM, Carvalho-Filho MA, Carvalheira JB, Prada PO, Hirabara SM, Schenka AA, Araújo EP, Vassallo J, Curi R, Velloso LA, Saad MJ.

Diabetes. 2007 Aug;56(8):1986-98. Epub 2007 May 22.PMID: 17519423 [PubMed - indexed for MEDLINE]Related articlesFree article

Adipose tissue macrophages, low grade inflammation and insulin resistance in human obesity.

Heilbronn LK, Campbell LV.

Curr Pharm Des. 2008;14(12):1225-30. Review.PMID: 18473870 [PubMed - indexed for MEDLINE]Related articles

Attenuation of the cardiovascular and metabolic complications of obesity in CD14 knockout mice.

Roncon-Albuquerque R Jr, Moreira-Rodrigues M, Faria B, Ferreira AP, Cerqueira C, Lourenço AP, Pestana M, von Hafe P, Leite-Moreira AF.

Life Sci. 2008 Sep 26;83(13-14):502-10. Epub 2008 Aug 12.PMID: 18761356 [PubMed - indexed for MEDLINE]Related articles

Obesity-induced inflammation in white adipose tissue is attenuated by loss of melanocortin-3 receptor signaling.

Ellacott KL, Murphy JG, Marks DL, Cone RD.

Endocrinology. 2007 Dec;148(12):6186-94. Epub 2007 Sep 27.PMID: 17901224 [PubMed - indexed for MEDLINE]Related articlesFree article

Chronic blockade of nitric oxide synthesis reduces adiposity and improves insulin resistance in high fat-induced obese mice.

Tsuchiya K, Sakai H, Suzuki N, Iwashima F, Yoshimoto T, Shichiri M, Hirata Y.

Endocrinology. 2007 Oct;148(10):4548-56. Epub 2007 Jun 21.PMID: 17584959 [PubMed - indexed for MEDLINE]Related articlesFree article