PubMed

Toward further mapping of the association between the IL2RA locus and type 1 diabetes.

Qu HQ, Montpetit A, Ge B, Hudson TJ, Polychronakos C.

Diabetes. 2007 Apr;56(4):1174-6.PMID: 17395754 [PubMed - indexed for MEDLINE]Related articlesFree article

Genetic association between the interleukin-2 receptor-alpha gene and mode of onset of type 1 diabetes in the Japanese population.

Kawasaki E, Awata T, Ikegami H, Kobayashi T, Maruyama T, Nakanishi K, Shimada A, Uga M, Kurihara S, Kawabata Y, Tanaka S, Kanazawa Y, Eguchi K; Japanese Study Group on Type 1 Diabetes Genetics.

J Clin Endocrinol Metab. 2009 Mar;94(3):947-52. Epub 2008 Dec 23.PMID: 19106270 [PubMed - indexed for MEDLINE]Related articles

Large-scale genetic fine mapping and genotype-phenotype associations implicate polymorphism in the IL2RA region in type 1 diabetes.

Lowe CE, Cooper JD, Brusko T, Walker NM, Smyth DJ, Bailey R, Bourget K, Plagnol V, Field S, Atkinson M, Clayton DG, Wicker LS, Todd JA.

Nat Genet. 2007 Sep;39(9):1074-82. Epub 2007 Aug 5.PMID: 17676041 [PubMed - indexed for MEDLINE]Related articles

IL2RA/CD25 gene polymorphisms: uneven association with multiple sclerosis (MS) and type 1 diabetes (T1D).

Alcina A, Fedetz M, Ndagire D, Fernández O, Leyva L, Guerrero M, Abad-Grau MM, Arnal C, Delgado C, Lucas M, Izquierdo G, Matesanz F.

PLoS One. 2009;4(1):e4137. Epub 2009 Jan 6.PMID: 19125193 [PubMed - indexed for MEDLINE]Related articlesFree article

A cis-acting regulatory variant in the IL2RA locus.

Qu HQ, Verlaan DJ, Ge B, Lu Y, Lam KC, Grabs R, Harmsen E, Hudson TJ, Hakonarson H, Pastinen T, Polychronakos C.

J Immunol. 2009 Oct 15;183(8):5158-62. Epub 2009 Sep 30.PMID: 19794070 [PubMed - indexed for MEDLINE]Related articles

Calsquestrin 1 (CASQ1) gene polymorphisms under chromosome 1q21 linkage peak are associated with type 2 diabetes in Northern European Caucasians.

Das SK, Chu W, Zhang Z, Hasstedt SJ, Elbein SC.

Diabetes. 2004 Dec;53(12):3300-6.PMID: 15561963 [PubMed - indexed for MEDLINE]Related articlesFree article

Localization of a type 1 diabetes locus in the IL2RA/CD25 region by use of tag single-nucleotide polymorphisms.

Vella A, Cooper JD, Lowe CE, Walker N, Nutland S, Widmer B, Jones R, Ring SM, McArdle W, Pembrey ME, Strachan DP, Dunger DB, Twells RC, Clayton DG, Todd JA.

Am J Hum Genet. 2005 May;76(5):773-9. Epub 2005 Mar 17.PMID: 15776395 [PubMed - indexed for MEDLINE]Related articlesFree article

Investigation of the estrogen receptor-alpha gene with type 2 diabetes and/or nephropathy in African-American and European-American populations.

Gallagher CJ, Keene KL, Mychaleckyj JC, Langefeld CD, Hirschhorn JN, Henderson BE, Gordon CJ, Freedman BI, Rich SS, Bowden DW, Sale MM.

Diabetes. 2007 Mar;56(3):675-84.PMID: 17327435 [PubMed - indexed for MEDLINE]Related articlesFree article

Complete molecular scanning of the human Fas gene: mutational analysis and linkage studies in families with type I diabetes mellitus. The Danish Study Group of Diabetes in Childhood and The Danish IDDM Epidemiology and Genetics Group.

Nolsøe RL, Kristiansen OP, Sangthongpitag K, Larsen ZM, Johannesen J, Karlsen AE, Pociot F, Nerup J, Verge CF, Mandrup-Poulsen T.

Diabetologia. 2000 Jun;43(6):800-8.PMID: 10907126 [PubMed - indexed for MEDLINE]Related articles

Lack of association of type 1 diabetes with the IL4R gene.

Qu HQ, Tessier MC, Fréchette R, Bacot F, Polychronakos C.

Diabetologia. 2006 May;49(5):958-61. Epub 2006 Mar 15.PMID: 16538488 [PubMed - indexed for MEDLINE]Related articles

Further evidence of a primary, causal association of the PTPN22 620W variant with type 1 diabetes.

Zoledziewska M, Perra C, Orrù V, Moi L, Frongia P, Congia M, Bottini N, Cucca F.

Diabetes. 2008 Jan;57(1):229-34. Epub 2007 Oct 12.PMID: 17934143 [PubMed - indexed for MEDLINE]Related articlesFree article

Risk alleles for multiple sclerosis identified by a genomewide study.

International Multiple Sclerosis Genetics Consortium, Hafler DA, Compston A, Sawcer S, Lander ES, Daly MJ, De Jager PL, de Bakker PI, Gabriel SB, Mirel DB, Ivinson AJ, Pericak-Vance MA, Gregory SG, Rioux JD, McCauley JL, Haines JL, Barcellos LF, Cree B, Oksenberg JR, Hauser SL.

N Engl J Med. 2007 Aug 30;357(9):851-62. Epub 2007 Jul 29.PMID: 17660530 [PubMed - indexed for MEDLINE]Related articlesFree article

PTPN22 Trp620 explains the association of chromosome 1p13 with type 1 diabetes and shows a statistical interaction with HLA class II genotypes.

Smyth DJ, Cooper JD, Howson JM, Walker NM, Plagnol V, Stevens H, Clayton DG, Todd JA.

Diabetes. 2008 Jun;57(6):1730-7. Epub 2008 Feb 27.PMID: 18305142 [PubMed - indexed for MEDLINE]Related articlesFree article

Association of the interleukin-2 receptor alpha (IL-2Ralpha)/CD25 gene region with Graves' disease using a multilocus test and tag SNPs.

Brand OJ, Lowe CE, Heward JM, Franklyn JA, Cooper JD, Todd JA, Gough SC.

Clin Endocrinol (Oxf). 2007 Apr;66(4):508-12.PMID: 17371467 [PubMed - indexed for MEDLINE]Related articles

Shared and distinct genetic variants in type 1 diabetes and celiac disease.

Smyth DJ, Plagnol V, Walker NM, Cooper JD, Downes K, Yang JH, Howson JM, Stevens H, McManus R, Wijmenga C, Heap GA, Dubois PC, Clayton DG, Hunt KA, van Heel DA, Todd JA.

N Engl J Med. 2008 Dec 25;359(26):2767-77. Epub 2008 Dec 10.PMID: 19073967 [PubMed - indexed for MEDLINE]Related articlesFree article

Association of the IL2RA/CD25 gene with juvenile idiopathic arthritis.

Hinks A, Ke X, Barton A, Eyre S, Bowes J, Worthington J, Thompson SD, Langefeld CD, Glass DN, Thomson W; UK Rheumatoid Arthritis Genetics Consortium; British Society of Paediatric and Adolescent Rheumatology Study Group.

Arthritis Rheum. 2009 Jan;60(1):251-7.PMID: 19116909 [PubMed - indexed for MEDLINE]Related articles

Molecular analysis of KCNJ10 on 1q as a candidate gene for Type 2 diabetes in Pima Indians.

Farook VS, Hanson RL, Wolford JK, Bogardus C, Prochazka M.

Diabetes. 2002 Nov;51(11):3342-6.PMID: 12401729 [PubMed - indexed for MEDLINE]Related articlesFree article

IFIH1 polymorphisms are significantly associated with type 1 diabetes and IFIH1 gene expression in peripheral blood mononuclear cells.

Liu S, Wang H, Jin Y, Podolsky R, Reddy MV, Pedersen J, Bode B, Reed J, Steed D, Anderson S, Yang P, Muir A, Steed L, Hopkins D, Huang Y, Purohit S, Wang CY, Steck AK, Montemari A, Eisenbarth G, Rewers M, She JX.

Hum Mol Genet. 2009 Jan 15;18(2):358-65. Epub 2008 Oct 16.PMID: 18927125 [PubMed - indexed for MEDLINE]Related articles

Cell-specific protein phenotypes for the autoimmune locus IL2RA using a genotype-selectable human bioresource.

Dendrou CA, Plagnol V, Fung E, Yang JH, Downes K, Cooper JD, Nutland S, Coleman G, Himsworth M, Hardy M, Burren O, Healy B, Walker NM, Koch K, Ouwehand WH, Bradley JR, Wareham NJ, Todd JA, Wicker LS.

Nat Genet. 2009 Sep;41(9):1011-5. Epub 2009 Aug 23.PMID: 19701192 [PubMed - indexed for MEDLINE]Related articles

Testing the possible negative association of type 1 diabetes and atopic disease by analysis of the interleukin 4 receptor gene.

Maier LM, Twells RC, Howson JM, Lam AC, Clayton DG, Smyth DJ, Savage D, Carson D, Patterson CC, Smink LJ, Walker NM, Burren OS, Nutland S, Rance H, Tuomilehto-Wolf E, Tuomilehto J, Guja C, Ionescu-Tirgoviste C, Undlien DE, Rønningen KS, Cucca F, Todd JA.

Genes Immun. 2003 Oct;4(7):469-75.PMID: 14551599 [PubMed - indexed for MEDLINE]Related articles