PubMed

Cx36-mediated coupling reduces beta-cell heterogeneity, confines the stimulating glucose concentration range, and affects insulin release kinetics.

Speier S, Gjinovci A, Charollais A, Meda P, Rupnik M.

Diabetes. 2007 Apr;56(4):1078-86.PMID: 17395748 [PubMed - indexed for MEDLINE]Related articlesFree article

Loss of connexin36 channels alters beta-cell coupling, islet synchronization of glucose-induced Ca2+ and insulin oscillations, and basal insulin release.

Ravier MA, Güldenagel M, Charollais A, Gjinovci A, Caille D, Söhl G, Wollheim CB, Willecke K, Henquin JC, Meda P.

Diabetes. 2005 Jun;54(6):1798-807.PMID: 15919802 [PubMed - indexed for MEDLINE]Related articlesFree article

Beta cells preferentially exchange cationic molecules via connexin 36 gap junction channels.

Charpantier E, Cancela J, Meda P.

Diabetologia. 2007 Nov;50(11):2332-41. Epub 2007 Sep 8.PMID: 17828386 [PubMed - indexed for MEDLINE]Related articles

Ghrelin uses Galphai2 and activates voltage-dependent K+ channels to attenuate glucose-induced Ca2+ signaling and insulin release in islet beta-cells: novel signal transduction of ghrelin.

Dezaki K, Kakei M, Yada T.

Diabetes. 2007 Sep;56(9):2319-27. Epub 2007 Jun 15.PMID: 17575083 [PubMed - indexed for MEDLINE]Related articlesFree article

A new conditional mouse mutant reveals specific expression and functions of connexin36 in neurons and pancreatic beta-cells.

Wellershaus K, Degen J, Deuchars J, Theis M, Charollais A, Caille D, Gauthier B, Janssen-Bienhold U, Sonntag S, Herrera P, Meda P, Willecke K.

Exp Cell Res. 2008 Mar 10;314(5):997-1012. Epub 2008 Jan 12.PMID: 18258229 [PubMed - indexed for MEDLINE]Related articles

ICER-1gamma overexpression drives palmitate-mediated connexin36 down-regulation in insulin-secreting cells.

Allagnat F, Alonso F, Martin D, Abderrahmani A, Waeber G, Haefliger JA.

J Biol Chem. 2008 Feb 29;283(9):5226-34. Epub 2007 Dec 11.PMID: 18073214 [PubMed - indexed for MEDLINE]Related articlesFree article

Enhanced glucose tolerance by SK4 channel inhibition in pancreatic beta-cells.

Düfer M, Gier B, Wolpers D, Krippeit-Drews P, Ruth P, Drews G.

Diabetes. 2009 Aug;58(8):1835-43. Epub 2009 Apr 28.PMID: 19401418 [PubMed - indexed for MEDLINE]Related articlesFree article

Cx36 makes channels coupling human pancreatic beta-cells, and correlates with insulin expression.

Serre-Beinier V, Bosco D, Zulianello L, Charollais A, Caille D, Charpantier E, Gauthier BR, Diaferia GR, Giepmans BN, Lupi R, Marchetti P, Deng S, Buhler L, Berney T, Cirulli V, Meda P.

Hum Mol Genet. 2009 Feb 1;18(3):428-39. Epub 2008 Nov 10.PMID: 19000992 [PubMed - indexed for MEDLINE]Related articles

Regulation by glucose of oscillatory electrical activity and 5-HT/insulin release from single mouse pancreatic islets in absence of functional K(ATP) channels.

Rosário LM, Barbosa RM, Antunes CM, Baldeiras IE, Silva AM, Tomé AR, Santos RM.

Endocr J. 2008 Aug;55(4):639-50. Epub 2008 May 21.PMID: 18493109 [PubMed - indexed for MEDLINE]Related articlesFree article

Connexin 36 controls synchronization of Ca2+ oscillations and insulin secretion in MIN6 cells.

Calabrese A, Zhang M, Serre-Beinier V, Caton D, Mas C, Satin LS, Meda P.

Diabetes. 2003 Feb;52(2):417-24.PMID: 12540616 [PubMed - indexed for MEDLINE]Related articlesFree article

Glucose represses connexin36 in insulin-secreting cells.

Allagnat F, Martin D, Condorelli DF, Waeber G, Haefliger JA.

J Cell Sci. 2005 Nov 15;118(Pt 22):5335-44. Epub 2005 Nov 1.PMID: 16263767 [PubMed - indexed for MEDLINE]Related articlesFree article

Glucose stimulates Ca2+ influx and insulin secretion in 2-week-old beta-cells lacking ATP-sensitive K+ channels.

Szollosi A, Nenquin M, Aguilar-Bryan L, Bryan J, Henquin JC.

J Biol Chem. 2007 Jan 19;282(3):1747-56. Epub 2006 Nov 30.PMID: 17138557 [PubMed - indexed for MEDLINE]Related articlesFree article

Deformation of network connectivity in the inferior olive of connexin 36-deficient mice is compensated by morphological and electrophysiological changes at the single neuron level.

De Zeeuw CI, Chorev E, Devor A, Manor Y, Van Der Giessen RS, De Jeu MT, Hoogenraad CC, Bijman J, Ruigrok TJ, French P, Jaarsma D, Kistler WM, Meier C, Petrasch-Parwez E, Dermietzel R, Sohl G, Gueldenagel M, Willecke K, Yarom Y.

J Neurosci. 2003 Jun 1;23(11):4700-11.PMID: 12805309 [PubMed - indexed for MEDLINE]Related articlesFree article

Non-steroidal anti-inflammatory drugs increase insulin release from beta cells by inhibiting ATP-sensitive potassium channels.

Li J, Zhang N, Ye B, Ju W, Orser B, Fox JE, Wheeler MB, Wang Q, Lu WY.

Br J Pharmacol. 2007 Jun;151(4):483-93. Epub 2007 Apr 16.PMID: 17435793 [PubMed - indexed for MEDLINE]Related articlesFree article

Voltage-gated ion channels in human pancreatic beta-cells: electrophysiological characterization and role in insulin secretion.

Braun M, Ramracheya R, Bengtsson M, Zhang Q, Karanauskaite J, Partridge C, Johnson PR, Rorsman P.

Diabetes. 2008 Jun;57(6):1618-28. Epub 2008 Apr 4.PMID: 18390794 [PubMed - indexed for MEDLINE]Related articlesFree article

Connexin36 mediates gap junctional coupling of alpha-ganglion cells in mouse retina.

Schubert T, Degen J, Willecke K, Hormuzdi SG, Monyer H, Weiler R.

J Comp Neurol. 2005 May 9;485(3):191-201.PMID: 15791644 [PubMed - indexed for MEDLINE]Related articles

Alkali pH directly activates ATP-sensitive K+ channels and inhibits insulin secretion in beta-cells.

Manning Fox JE, Karaman G, Wheeler MB.

Biochem Biophys Res Commun. 2006 Nov 17;350(2):492-7. Epub 2006 Sep 26.PMID: 17011513 [PubMed - indexed for MEDLINE]Related articles

Connexin36 and pancreatic beta-cell functions.

Nlend RN, Michon L, Bavamian S, Boucard N, Caille D, Cancela J, Charollais A, Charpantier E, Klee P, Peyrou M, Populaire C, Zulianello L, Meda P.

Arch Physiol Biochem. 2006 Apr;112(2):74-81. Review.PMID: 16931449 [PubMed - indexed for MEDLINE]Related articles

Novel mechanism of chronic exposure of oleic acid-induced insulin release impairment in rat pancreatic beta-cells.

Kudo T, Wu J, Ogawa Y, Suga S, Hasegawa N, Suda T, Mizukami H, Yagihashi S, Wakui M.

J Pharmacol Exp Ther. 2006 Sep;318(3):1203-10. Epub 2006 Jun 6.PMID: 16757537 [PubMed - indexed for MEDLINE]Related articlesFree article

Connexin36 mediates spike synchrony in olfactory bulb glomeruli.

Christie JM, Bark C, Hormuzdi SG, Helbig I, Monyer H, Westbrook GL.

Neuron. 2005 Jun 2;46(5):761-72.PMID: 15924862 [PubMed - indexed for MEDLINE]Related articles