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    Results: 1 to 20 of 292

    1.

    Minimal impact of a de novo-expressed beta-cell autoantigen on spontaneous diabetes development in NOD mice.

    Martinic MM, Juedes AE, Bresson D, Homann D, Skak K, Huber C, Ling E, Ejrnaes M, Wolfe T, Togher L, Christen U, von Herrath MG.

    Diabetes. 2007 Apr;56(4):1059-68.PMID: 17395746 [PubMed - indexed for MEDLINE]Related articlesFree article

    2.

    Genetic and therapeutic control of diabetogenic CD8+ T cells.

    Santamaria P.

    Novartis Found Symp. 2008;292:130-6; discussion 136-45, 202-3.PMID: 19209463 [PubMed - indexed for MEDLINE]Related articles

    3.

    Identification of CD4+ T cell-specific epitopes of islet-specific glucose-6-phosphatase catalytic subunit-related protein: a novel beta cell autoantigen in type 1 diabetes.

    Mukherjee R, Wagar D, Stephens TA, Lee-Chan E, Singh B.

    J Immunol. 2005 May 1;174(9):5306-15.PMID: 15843527 [PubMed - indexed for MEDLINE]Related articlesFree article

    4.

    "Humanized" HLA transgenic NOD mice to identify pancreatic beta cell autoantigens of potential clinical relevance to type 1 diabetes.

    Serreze DV, Marron MP, Dilorenzo TP.

    Ann N Y Acad Sci. 2007 Apr;1103:103-11. Epub 2007 Mar 21.PMID: 17376821 [PubMed - indexed for MEDLINE]Related articles

    5.

    Responses against islet antigens in NOD mice are prevented by tolerance to proinsulin but not IGRP.

    Krishnamurthy B, Dudek NL, McKenzie MD, Purcell AW, Brooks AG, Gellert S, Colman PG, Harrison LC, Lew AM, Thomas HE, Kay TW.

    J Clin Invest. 2006 Dec;116(12):3258-65.PMID: 17143333 [PubMed - indexed for MEDLINE]Related articlesFree article

    6.

    HLA-A*0201-restricted T cells from humanized NOD mice recognize autoantigens of potential clinical relevance to type 1 diabetes.

    Takaki T, Marron MP, Mathews CE, Guttmann ST, Bottino R, Trucco M, DiLorenzo TP, Serreze DV.

    J Immunol. 2006 Mar 1;176(5):3257-65.PMID: 16493087 [PubMed - indexed for MEDLINE]Related articlesFree article

    7.

    Identification of the beta cell antigen targeted by a prevalent population of pathogenic CD8+ T cells in autoimmune diabetes.

    Lieberman SM, Evans AM, Han B, Takaki T, Vinnitskaya Y, Caldwell JA, Serreze DV, Shabanowitz J, Hunt DF, Nathenson SG, Santamaria P, DiLorenzo TP.

    Proc Natl Acad Sci U S A. 2003 Jul 8;100(14):8384-8. Epub 2003 Jun 18.PMID: 12815107 [PubMed - indexed for MEDLINE]Related articlesFree article

    8.

    RegII is a beta-cell protein and autoantigen in diabetes of NOD mice.

    Gurr W, Shaw M, Li Y, Sherwin R.

    Diabetes. 2007 Jan;56(1):34-40.PMID: 17192462 [PubMed - indexed for MEDLINE]Related articlesFree article

    9.

    On the pathogenicity of autoantigen-specific T-cell receptors.

    Burton AR, Vincent E, Arnold PY, Lennon GP, Smeltzer M, Li CS, Haskins K, Hutton J, Tisch RM, Sercarz EE, Santamaria P, Workman CJ, Vignali DA.

    Diabetes. 2008 May;57(5):1321-30. Epub 2008 Feb 25.PMID: 18299317 [PubMed - indexed for MEDLINE]Related articlesFree article

    10.

    Different diabetogenic potential of autoaggressive CD8+ clones associated with IFN-gamma-inducible protein 10 (CXC chemokine ligand 10) production but not cytokine expression, cytolytic activity, or homing characteristics.

    Ejrnaes M, Videbaek N, Christen U, Cooke A, Michelsen BK, von Herrath M.

    J Immunol. 2005 Mar 1;174(5):2746-55.PMID: 15728483 [PubMed - indexed for MEDLINE]Related articlesFree article

    11.

    The target cell response to cytokines governs the autoreactive T cell repertoire in the pancreas of NOD mice.

    Hultcrantz M, Jacobson S, Hill NJ, Santamaria P, Flodström-Tullberg M.

    Diabetologia. 2009 Feb;52(2):299-305. Epub 2008 Nov 25.PMID: 19031069 [PubMed - indexed for MEDLINE]Related articles

    12.

    Autoreactive diabetogenic T-cells in NOD mice can efficiently expand from a greatly reduced precursor pool.

    Serreze DV, Johnson EA, Chapman HD, Graser RT, Marron MP, DiLorenzo TP, Silveira P, Yoshimura Y, Nathenson SG, Joyce S.

    Diabetes. 2001 Sep;50(9):1992-2000.PMID: 11522664 [PubMed - indexed for MEDLINE]Related articlesFree article

    13.

    Focal expression of interleukin-2 does not break unresponsiveness to "self" (viral) antigen expressed in beta cells but enhances development of autoimmune disease (diabetes) after initiation of an anti-self immune response.

    von Herrath MG, Allison J, Miller JF, Oldstone MB.

    J Clin Invest. 1995 Feb;95(2):477-85.PMID: 7860729 [PubMed - indexed for MEDLINE]Related articlesFree article

    14.

    Human clonal CD8 autoreactivity to an IGRP islet epitope shared between mice and men.

    Unger WW, Pinkse GG, Mulder-van der Kracht S, van der Slik AR, Kester MG, Ossendorp F, Drijfhout JW, Serreze DV, Roep BO.

    Ann N Y Acad Sci. 2007 Apr;1103:192-5. Epub 2007 Mar 21.PMID: 17376840 [PubMed - indexed for MEDLINE]Related articles

    15.

    Prospective prediction of spontaneous but not recurrent autoimmune diabetes in the non-obese diabetic mouse.

    Trudeau JD, Chandler T, Soukhatcheva G, Verchere CB, Tan R.

    Diabetologia. 2007 May;50(5):1015-23. Epub 2007 Mar 2.PMID: 17334749 [PubMed - indexed for MEDLINE]Related articles

    16.

    Islet-specific expression of CXCL10 causes spontaneous islet infiltration and accelerates diabetes development.

    Rhode A, Pauza ME, Barral AM, Rodrigo E, Oldstone MB, von Herrath MG, Christen U.

    J Immunol. 2005 Sep 15;175(6):3516-24.PMID: 16148094 [PubMed - indexed for MEDLINE]Related articlesFree article

    17.

    A Reg family protein is overexpressed in islets from a patient with new-onset type 1 diabetes and acts as T-cell autoantigen in NOD mice.

    Gurr W, Yavari R, Wen L, Shaw M, Mora C, Christa L, Sherwin RS.

    Diabetes. 2002 Feb;51(2):339-46.PMID: 11812740 [PubMed - indexed for MEDLINE]Related articlesFree article

    18.

    Proinsulin: a unique autoantigen triggering autoimmune diabetes.

    You S, Chatenoud L.

    J Clin Invest. 2006 Dec;116(12):3108-10.PMID: 17143326 [PubMed - indexed for MEDLINE]Related articlesFree article

    19.

    Selective delivery of beta cell antigen to dendritic cells in vivo leads to deletion and tolerance of autoreactive CD8+ T cells in NOD mice.

    Mukhopadhaya A, Hanafusa T, Jarchum I, Chen YG, Iwai Y, Serreze DV, Steinman RM, Tarbell KV, DiLorenzo TP.

    Proc Natl Acad Sci U S A. 2008 Apr 29;105(17):6374-9. Epub 2008 Apr 22.PMID: 18430797 [PubMed - indexed for MEDLINE]Related articlesFree article

    20.

    Early autoimmune destruction of islet grafts is associated with a restricted repertoire of IGRP-specific CD8+ T cells in diabetic nonobese diabetic mice.

    Wong CP, Li L, Frelinger JA, Tisch R.

    J Immunol. 2006 Feb 1;176(3):1637-44.PMID: 16424193 [PubMed - indexed for MEDLINE]Related articlesFree article

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