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    Results: 1 to 20 of 1800

    1.

    Peroxisome proliferator-activated receptor gamma1 expression is diminished in human osteoarthritic cartilage and is downregulated by interleukin-1beta in articular chondrocytes.

    Afif H, Benderdour M, Mfuna-Endam L, Martel-Pelletier J, Pelletier JP, Duval N, Fahmi H.

    Arthritis Res Ther. 2007;9(2):R31.

    PMID:
    17386086
    [PubMed - indexed for MEDLINE]
    Free PMC Article
    2.

    Activation of proteinase-activated receptor 2 in human osteoarthritic cartilage upregulates catabolic and proinflammatory pathways capable of inducing cartilage degradation: a basic science study.

    Boileau C, Amiable N, Martel-Pelletier J, Fahmi H, Duval N, Pelletier JP.

    Arthritis Res Ther. 2007;9(6):R121.

    PMID:
    18031579
    [PubMed - indexed for MEDLINE]
    Free PMC Article
    3.

    Increased expression of lipocalin-type prostaglandin D2 synthase in osteoarthritic cartilage.

    Zayed N, Li X, Chabane N, Benderdour M, Martel-Pelletier J, Pelletier JP, Duval N, Fahmi H.

    Arthritis Res Ther. 2008;10(6):R146. Epub 2008 Dec 18.

    PMID:
    19094210
    [PubMed - indexed for MEDLINE]
    Free PMC Article
    4.

    Expression and regulation of microsomal prostaglandin E synthase-1 in human osteoarthritic cartilage and chondrocytes.

    Li X, Afif H, Cheng S, Martel-Pelletier J, Pelletier JP, Ranger P, Fahmi H.

    J Rheumatol. 2005 May;32(5):887-95.

    PMID:
    15868626
    [PubMed - indexed for MEDLINE]
    5.

    Advanced glycation end products downregulates peroxisome proliferator-activated receptor γ expression in cultured rabbit chondrocyte through MAPK pathway.

    Yang Q, Chen C, Wu S, Zhang Y, Mao X, Wang W.

    Eur J Pharmacol. 2010 Dec 15;649(1-3):108-14. Epub 2010 Sep 20.

    PMID:
    20863825
    [PubMed - indexed for MEDLINE]
    8.

    Peroxisome proliferator-activated receptor-gamma down-regulates chondrocyte matrix metalloproteinase-1 via a novel composite element.

    François M, Richette P, Tsagris L, Raymondjean M, Fulchignoni-Lataud MC, Forest C, Savouret JF, Corvol MT.

    J Biol Chem. 2004 Jul 2;279(27):28411-8. Epub 2004 Apr 16.

    PMID:
    15090544
    [PubMed - indexed for MEDLINE]
    Free Article
    9.

    The catabolic pathway mediated by Toll-like receptors in human osteoarthritic chondrocytes.

    Kim HA, Cho ML, Choi HY, Yoon CS, Jhun JY, Oh HJ, Kim HY.

    Arthritis Rheum. 2006 Jul;54(7):2152-63.

    PMID:
    16802353
    [PubMed - indexed for MEDLINE]
    Free Article
    10.

    Involvement of protein kinase Czeta in interleukin-1beta induction of ADAMTS-4 and type 2 nitric oxide synthase via NF-kappaB signaling in primary human osteoarthritic chondrocytes.

    Chockalingam PS, Varadarajan U, Sheldon R, Fortier E, LaVallie ER, Morris EA, Yaworsky PJ, Majumdar MK.

    Arthritis Rheum. 2007 Dec;56(12):4074-83.

    PMID:
    18050214
    [PubMed - indexed for MEDLINE]
    Free Article
    11.

    Induction of matrix metalloproteinase-13 gene expression by TNF-alpha is mediated by MAP kinases, AP-1, and NF-kappaB transcription factors in articular chondrocytes.

    Liacini A, Sylvester J, Li WQ, Huang W, Dehnade F, Ahmad M, Zafarullah M.

    Exp Cell Res. 2003 Aug 1;288(1):208-17.

    PMID:
    12878172
    [PubMed - indexed for MEDLINE]
    13.

    Calcium/calmodulin-dependent protein kinase II in human articular chondrocytes.

    Shimazaki A, Wright MO, Elliot K, Salter DM, Millward-Sadler SJ.

    Biorheology. 2006;43(3-4):223-33.

    PMID:
    16912396
    [PubMed - indexed for MEDLINE]
    14.

    Regulation of prostaglandin E(2) synthesis in cells derived from chondrocytes of patients with osteoarthritis.

    Shimpo H, Sakai T, Kondo S, Mishima S, Yoda M, Hiraiwa H, Ishiguro N.

    J Orthop Sci. 2009 Sep;14(5):611-7. Epub 2009 Oct 3.

    PMID:
    19802674
    [PubMed - indexed for MEDLINE]
    15.

    Interleukin-1alpha stimulates proinflammatory cytokine expression in human cardiac myofibroblasts.

    Turner NA, Das A, Warburton P, O'Regan DJ, Ball SG, Porter KE.

    Am J Physiol Heart Circ Physiol. 2009 Sep;297(3):H1117-27. Epub 2009 Jul 31.

    PMID:
    19648252
    [PubMed - indexed for MEDLINE]
    Free Article
    16.

    Protein kinase Czeta is up-regulated in osteoarthritic cartilage and is required for activation of NF-kappaB by tumor necrosis factor and interleukin-1 in articular chondrocytes.

    LaVallie ER, Chockalingam PS, Collins-Racie LA, Freeman BA, Keohan CC, Leitges M, Dorner AJ, Morris EA, Majumdar MK, Arai M.

    J Biol Chem. 2006 Aug 25;281(34):24124-37. Epub 2006 Jun 23.

    PMID:
    16798739
    [PubMed - indexed for MEDLINE]
    Free Article
    17.

    Up-regulation of microsomal prostaglandin E synthase 1 in osteoarthritic human cartilage: critical roles of the ERK-1/2 and p38 signaling pathways.

    Masuko-Hongo K, Berenbaum F, Humbert L, Salvat C, Goldring MB, Thirion S.

    Arthritis Rheum. 2004 Sep;50(9):2829-38.

    PMID:
    15457451
    [PubMed - indexed for MEDLINE]
    Free Article
    18.

    IL-17 stimulates MMP-1 expression in primary human cardiac fibroblasts via p38 MAPK- and ERK1/2-dependent C/EBP-beta , NF-kappaB, and AP-1 activation.

    Cortez DM, Feldman MD, Mummidi S, Valente AJ, Steffensen B, Vincenti M, Barnes JL, Chandrasekar B.

    Am J Physiol Heart Circ Physiol. 2007 Dec;293(6):H3356-65. Epub 2007 Oct 5.

    PMID:
    17921324
    [PubMed - indexed for MEDLINE]
    Free Article
    19.

    MyD88, IRAK1 and TRAF6 knockdown in human chondrocytes inhibits interleukin-1-induced matrix metalloproteinase-13 gene expression and promoter activity by impairing MAP kinase activation.

    Ahmad R, Sylvester J, Zafarullah M.

    Cell Signal. 2007 Dec;19(12):2549-57. Epub 2007 Aug 25.

    PMID:
    17905570
    [PubMed - indexed for MEDLINE]
    20.

    Dynamic compression counteracts IL-1beta induced inducible nitric oxide synthase and cyclo-oxygenase-2 expression in chondrocyte/agarose constructs.

    Chowdhury TT, Arghandawi S, Brand J, Akanji OO, Bader DL, Salter DM, Lee DA.

    Arthritis Res Ther. 2008;10(2):R35. Epub 2008 Mar 18.

    PMID:
    18348730
    [PubMed - indexed for MEDLINE]
    Free PMC Article

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