PubMed

PPARalpha agonists suppress osteopontin expression in macrophages and decrease plasma levels in patients with type 2 diabetes.

Nakamachi T, Nomiyama T, Gizard F, Heywood EB, Jones KL, Zhao Y, Fuentes L, Takebayashi K, Aso Y, Staels B, Inukai T, Bruemmer D.

Diabetes. 2007 Jun;56(6):1662-70. Epub 2007 Mar 14.PMID: 17360982 [PubMed - indexed for MEDLINE]Related articlesFree article

Liver x receptor agonists inhibit cytokine-induced osteopontin expression in macrophages through interference with activator protein-1 signaling pathways.

Ogawa D, Stone JF, Takata Y, Blaschke F, Chu VH, Towler DA, Law RE, Hsueh WA, Bruemmer D.

Circ Res. 2005 Apr 15;96(7):e59-67. Epub 2005 Mar 24.PMID: 15790955 [PubMed - indexed for MEDLINE]Related articlesFree article

Matrix metalloproteinase-12 gene regulation by a PPAR alpha agonist in human monocyte-derived macrophages.

Souissi IJ, Billiet L, Cuaz-Pérolin C, Slimane MN, Rouis M.

Exp Cell Res. 2008 Nov 1;314(18):3405-14. Epub 2008 Sep 18.PMID: 18823978 [PubMed - indexed for MEDLINE]Related articles

Peroxisome proliferator-activated receptor alpha negatively regulates the vascular inflammatory gene response by negative cross-talk with transcription factors NF-kappaB and AP-1.

Delerive P, De Bosscher K, Besnard S, Vanden Berghe W, Peters JM, Gonzalez FJ, Fruchart JC, Tedgui A, Haegeman G, Staels B.

J Biol Chem. 1999 Nov 5;274(45):32048-54.PMID: 10542237 [PubMed - indexed for MEDLINE]Related articlesFree article

Differential regulation of macrophage peroxisome proliferator-activated receptor expression by glucose : role of peroxisome proliferator-activated receptors in lipoprotein lipase gene expression.

Sartippour MR, Renier G.

Arterioscler Thromb Vasc Biol. 2000 Jan;20(1):104-10.PMID: 10634806 [PubMed - indexed for MEDLINE]Related articlesFree article

Peroxisome-proliferator-activated receptor alpha agonists inhibit cyclo-oxygenase 2 and vascular endothelial growth factor transcriptional activation in human colorectal carcinoma cells via inhibition of activator protein-1.

Grau R, Punzón C, Fresno M, Iñiguez MA.

Biochem J. 2006 Apr 1;395(1):81-8.PMID: 16343055 [PubMed - indexed for MEDLINE]Related articlesFree article

The direct antioxidative and anti-inflammatory effects of peroxisome proliferator-activated receptors ligands are associated with the inhibition of angiotensin converting enzyme expression in streptozotocin-induced diabetic rat aorta.

Toba H, Miki S, Shimizu T, Yoshimura A, Inoue R, Sawai N, Tsukamoto R, Murakami M, Morita Y, Nakayama Y, Kobara M, Nakata T.

Eur J Pharmacol. 2006 Nov 7;549(1-3):124-32. Epub 2006 Aug 30.PMID: 16979161 [PubMed - indexed for MEDLINE]Related articles

Potential relationship between hepatobiliary osteopontin and peroxisome proliferator-activated receptor alpha expression following ethanol-associated hepatic injury in vivo and in vitro.

Lee JH, Banerjee A, Ueno Y, Ramaiah SK.

Toxicol Sci. 2008 Nov;106(1):290-9. Epub 2008 Aug 14.PMID: 18703563 [PubMed - indexed for MEDLINE]Related articlesFree article

Macrophage expression of peroxisome proliferator-activated receptor-alpha reduces atherosclerosis in low-density lipoprotein receptor-deficient mice.

Babaev VR, Ishiguro H, Ding L, Yancey PG, Dove DE, Kovacs WJ, Semenkovich CF, Fazio S, Linton MF.

Circulation. 2007 Sep 18;116(12):1404-12. Epub 2007 Aug 27.PMID: 17724261 [PubMed - indexed for MEDLINE]Related articlesFree article

Thioredoxin-1 and its natural inhibitor, vitamin D3 up-regulated protein 1, are differentially regulated by PPARalpha in human macrophages.

Billiet L, Furman C, Cuaz-Pérolin C, Paumelle R, Raymondjean M, Simmet T, Rouis M.

J Mol Biol. 2008 Dec 19;384(3):564-76. Epub 2008 Oct 2.PMID: 18848838 [PubMed - indexed for MEDLINE]Related articles

Effects of peroxisome proliferator-activated receptor ligands, bezafibrate and fenofibrate, on adiponectin level.

Hiuge A, Tenenbaum A, Maeda N, Benderly M, Kumada M, Fisman EZ, Tanne D, Matas Z, Hibuse T, Fujita K, Nishizawa H, Adler Y, Motro M, Kihara S, Shimomura I, Behar S, Funahashi T.

Arterioscler Thromb Vasc Biol. 2007 Mar;27(3):635-41. Epub 2006 Dec 28.PMID: 17194889 [PubMed - indexed for MEDLINE]Related articlesFree article

PPARgamma ligand inhibits osteopontin gene expression through interference with binding of nuclear factors to A/T-rich sequence in THP-1 cells.

Oyama Y, Akuzawa N, Nagai R, Kurabayashi M.

Circ Res. 2002 Feb 22;90(3):348-55.PMID: 11861425 [PubMed - indexed for MEDLINE]Related articlesFree article

The inhibition of the human cholesterol 7alpha-hydroxylase gene (CYP7A1) promoter by fibrates in cultured cells is mediated via the liver x receptor alpha and peroxisome proliferator-activated receptor alpha heterodimer.

Gbaguidi GF, Agellon LB.

Nucleic Acids Res. 2004 Feb 11;32(3):1113-21. Print 2004.PMID: 14960721 [PubMed - indexed for MEDLINE]Related articlesFree article

Effect of peroxisome proliferator-activated receptor alpha on human angiotensinogen promoter.

Shimamoto Y, Hirota K, Fukamizu A.

Int J Mol Med. 2004 May;13(5):729-33.PMID: 15067378 [PubMed - indexed for MEDLINE]Related articles

Bezafibrate is a dual ligand for PPARalpha and PPARbeta: studies using null mice.

Peters JM, Aoyama T, Burns AM, Gonzalez FJ.

Biochim Biophys Acta. 2003 Jun 10;1632(1-3):80-9.PMID: 12782154 [PubMed - indexed for MEDLINE]Related articles

Osteopontin in rat renal fibroblasts: functional properties and transcriptional regulation by aldosterone.

Irita J, Okura T, Kurata M, Miyoshi K, Fukuoka T, Higaki J.

Hypertension. 2008 Feb;51(2):507-13. Epub 2007 Dec 24.PMID: 18158341 [PubMed - indexed for MEDLINE]Related articlesFree article

Peroxisome proliferator-activated receptors (PPAR) agonists affect cell viability, apoptosis and expression of cell cycle related proteins in cell lines of glial brain tumors.

Strakova N, Ehrmann J, Bartos J, Malikova J, Dolezel J, Kolar Z.

Neoplasma. 2005;52(2):126-36.PMID: 15800711 [PubMed - indexed for MEDLINE]Related articles

Agonists of the peroxisome proliferator-activated receptor alpha induce a fiber-type-selective transcriptional response in rat skeletal muscle.

De Souza AT, Cornwell PD, Dai X, Caguyong MJ, Ulrich RG.

Toxicol Sci. 2006 Aug;92(2):578-86. Epub 2006 May 17.PMID: 16707586 [PubMed - indexed for MEDLINE]Related articlesFree article

Liver-specific peroxisome proliferator-activated receptor alpha target gene regulation by the angiotensin type 1 receptor blocker telmisartan.

Clemenz M, Frost N, Schupp M, Caron S, Foryst-Ludwig A, Böhm C, Hartge M, Gust R, Staels B, Unger T, Kintscher U.

Diabetes. 2008 May;57(5):1405-13. Epub 2008 Jan 9.PMID: 18184928 [PubMed - indexed for MEDLINE]Related articlesFree article

A nuclear receptor corepressor-dependent pathway mediates suppression of cytokine-induced C-reactive protein gene expression by liver X receptor.

Blaschke F, Takata Y, Caglayan E, Collins A, Tontonoz P, Hsueh WA, Tangirala RK.

Circ Res. 2006 Dec 8;99(12):e88-99. Epub 2006 Nov 16.PMID: 17110595 [PubMed - indexed for MEDLINE]Related articlesFree article