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    Results: 1 to 20 of 141

    1.

    Global assessment of regulation of phosphorylation of insulin receptor substrate-1 by insulin in vivo in human muscle.

    Yi Z, Langlais P, De Filippis EA, Luo M, Flynn CR, Schroeder S, Weintraub ST, Mapes R, Mandarino LJ.

    Diabetes. 2007 Jun;56(6):1508-16. Epub 2007 Mar 14.PMID: 17360977 [PubMed - indexed for MEDLINE]Related articlesFree article

    2.

    Identification of insulin receptor substrate 1 serine/threonine phosphorylation sites using mass spectrometry analysis: regulatory role of serine 1223.

    Luo M, Reyna S, Wang L, Yi Z, Carroll C, Dong LQ, Langlais P, Weintraub ST, Mandarino LJ.

    Endocrinology. 2005 Oct;146(10):4410-6. Epub 2005 Jul 14.PMID: 16020478 [PubMed - indexed for MEDLINE]Related articlesFree article

    3.

    Glucocorticoid regulation of insulin receptor and substrate IRS-1 tyrosine phosphorylation in rat skeletal muscle in vivo.

    Giorgino F, Almahfouz A, Goodyear LJ, Smith RJ.

    J Clin Invest. 1993 May;91(5):2020-30.PMID: 7683695 [PubMed - indexed for MEDLINE]Related articlesFree article

    4.

    Reduced activation of phosphatidylinositol-3 kinase and increased serine 636 phosphorylation of insulin receptor substrate-1 in primary culture of skeletal muscle cells from patients with type 2 diabetes.

    Bouzakri K, Roques M, Gual P, Espinosa S, Guebre-Egziabher F, Riou JP, Laville M, Le Marchand-Brustel Y, Tanti JF, Vidal H.

    Diabetes. 2003 Jun;52(6):1319-25.PMID: 12765939 [PubMed - indexed for MEDLINE]Related articlesFree article

    5.

    Rosiglitazone improves downstream insulin receptor signaling in type 2 diabetic patients.

    Miyazaki Y, He H, Mandarino LJ, DeFronzo RA.

    Diabetes. 2003 Aug;52(8):1943-50.PMID: 12882909 [PubMed - indexed for MEDLINE]Related articlesFree article

    6.

    Dietary protein deprivation decreases the serine phosphorylation of insulin receptor substrate-1 in rat skeletal muscle.

    Toyoshima Y, Ohne Y, Takahashi SI, Noguchi T, Kato H.

    J Mol Endocrinol. 2004 Apr;32(2):519-31.PMID: 15072556 [PubMed - indexed for MEDLINE]Related articlesFree article

    7.

    Muscle-specific IRS-1 Ser->Ala transgenic mice are protected from fat-induced insulin resistance in skeletal muscle.

    Morino K, Neschen S, Bilz S, Sono S, Tsirigotis D, Reznick RM, Moore I, Nagai Y, Samuel V, Sebastian D, White M, Philbrick W, Shulman GI.

    Diabetes. 2008 Oct;57(10):2644-51. Epub 2008 Jul 15.PMID: 18633112 [PubMed - indexed for MEDLINE]Related articlesFree article

    8.

    Short-term in vivo inhibition of insulin receptor substrate-1 expression leads to insulin resistance, hyperinsulinemia, and increased adiposity.

    Araújo EP, De Souza CT, Gasparetti AL, Ueno M, Boschero AC, Saad MJ, Velloso LA.

    Endocrinology. 2005 Mar;146(3):1428-37. Epub 2004 Nov 18.PMID: 15550510 [PubMed - indexed for MEDLINE]Related articlesFree article

    9.

    Reduced mitochondrial density and increased IRS-1 serine phosphorylation in muscle of insulin-resistant offspring of type 2 diabetic parents.

    Morino K, Petersen KF, Dufour S, Befroy D, Frattini J, Shatzkes N, Neschen S, White MF, Bilz S, Sono S, Pypaert M, Shulman GI.

    J Clin Invest. 2005 Dec;115(12):3587-93. Epub 2005 Nov 10.PMID: 16284649 [PubMed - indexed for MEDLINE]Related articlesFree article

    10.

    Serine phosphorylation proximal to its phosphotyrosine binding domain inhibits insulin receptor substrate 1 function and promotes insulin resistance.

    Liu YF, Herschkovitz A, Boura-Halfon S, Ronen D, Paz K, Leroith D, Zick Y.

    Mol Cell Biol. 2004 Nov;24(21):9668-81.PMID: 15485932 [PubMed - indexed for MEDLINE]Related articlesFree article

    11.

    Phosphorylation of human insulin receptor substrate-1 at Serine 629 plays a positive role in insulin signaling.

    Luo M, Langlais P, Yi Z, Lefort N, De Filippis EA, Hwang H, Christ-Roberts CY, Mandarino LJ.

    Endocrinology. 2007 Oct;148(10):4895-905. Epub 2007 Jul 19.PMID: 17640984 [PubMed - indexed for MEDLINE]Related articlesFree article

    12.

    Disruption of the availability of amino acids induces a rapid reduction of serine phosphorylation of insulin receptor substrate-1 in vivo and in vitro.

    Ohne Y, Toyoshima Y, Kato H.

    Biosci Biotechnol Biochem. 2005 May;69(5):989-98.PMID: 15914920 [PubMed - indexed for MEDLINE]Related articlesFree article

    13.

    Identification of phosphorylation sites in insulin receptor substrate-1 by hypothesis-driven high-performance liquid chromatography-electrospray ionization tandem mass spectrometry.

    Yi Z, Luo M, Carroll CA, Weintraub ST, Mandarino LJ.

    Anal Chem. 2005 Sep 1;77(17):5693-9.PMID: 16131083 [PubMed - indexed for MEDLINE]Related articles

    14.

    [Effects of insulin receptor substrate-1 and its serine phosphorylation and tyrosine phosphorylation on insulin resistance in skeletal muscle cells in the state of sepsis: experiment with rats]

    Yan XW, Li WQ, Wang XD, Li JS, Li N.

    Zhonghua Yi Xue Za Zhi. 2006 Nov 7;86(41):2922-7. Chinese. PMID: 17288791 [PubMed - indexed for MEDLINE]Related articles

    15.

    Alteration in insulin action: role of IRS-1 serine phosphorylation in the retroregulation of insulin signalling.

    Tanti JF, Gual P, Grémeaux T, Gonzalez T, Barrès R, Le Marchand-Brustel Y.

    Ann Endocrinol (Paris). 2004 Feb;65(1):43-8. Review.PMID: 15122091 [PubMed - indexed for MEDLINE]Related articles

    16.

    IRS-1 serine phosphorylation and insulin resistance in skeletal muscle from pancreas transplant recipients.

    Bouzakri K, Karlsson HK, Vestergaard H, Madsbad S, Christiansen E, Zierath JR.

    Diabetes. 2006 Mar;55(3):785-91.PMID: 16505244 [PubMed - indexed for MEDLINE]Related articlesFree article

    17.

    RhoA/Rho kinase blocks muscle differentiation via serine phosphorylation of insulin receptor substrate-1 and -2.

    Lim MJ, Choi KJ, Ding Y, Kim JH, Kim BS, Kim YH, Lee J, Choe W, Kang I, Ha J, Yoon KS, Kim SS.

    Mol Endocrinol. 2007 Sep;21(9):2282-93. Epub 2007 Jun 19. Erratum in: Mol Endocrinol. 2007 Dec;21(12):2955. PMID: 17579208 [PubMed - indexed for MEDLINE]Related articlesFree article

    18.

    Reversal of insulin resistance postpartum is linked to enhanced skeletal muscle insulin signaling.

    Kirwan JP, Varastehpour A, Jing M, Presley L, Shao J, Friedman JE, Catalano PM.

    J Clin Endocrinol Metab. 2004 Sep;89(9):4678-84.PMID: 15356080 [PubMed - indexed for MEDLINE]Related articlesFree article

    19.

    Insulin-stimulated insulin receptor substrate-2-associated phosphatidylinositol 3-kinase activity is enhanced in human skeletal muscle after exercise.

    Howlett KF, Sakamoto K, Yu H, Goodyear LJ, Hargreaves M.

    Metabolism. 2006 Aug;55(8):1046-52.PMID: 16839840 [PubMed - indexed for MEDLINE]Related articles

    20.

    [Relationship between tyrosine phosphorylation and protein expression of insulin receptor substrate-1 and insulin resistance in gestational diabetes mellitus]

    Qu HM, Ye YH, Peng W, Zhan Y.

    Zhonghua Fu Chan Ke Za Zhi. 2007 Apr;42(4):249-52. Chinese. PMID: 17631765 [PubMed - indexed for MEDLINE]Related articles

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