PubMed

Glucose-dependent modulation of insulin secretion and intracellular calcium ions by GKA50, a glucokinase activator.

Johnson D, Shepherd RM, Gill D, Gorman T, Smith DM, Dunne MJ.

Diabetes. 2007 Jun;56(6):1694-702. Epub 2007 Mar 14.PMID: 17360975 [PubMed - indexed for MEDLINE]Related articlesFree article

Glucose triggers protein kinase A-dependent insulin secretion in mouse pancreatic islets through activation of the K+ATP channel-dependent pathway.

Thams P, Anwar MR, Capito K.

Eur J Endocrinol. 2005 Apr;152(4):671-7.PMID: 15817925 [PubMed - indexed for MEDLINE]Related articlesFree article

Imidazoline NNC77-0074 stimulates insulin secretion and inhibits glucagon release by control of Ca(2+)-dependent exocytosis in pancreatic alpha- and beta-cells.

Høy M, Olsen HL, Andersen HS, Bokvist K, Buschard K, Hansen J, Jacobsen P, Petersen JS, Rorsman P, Gromada J.

Eur J Pharmacol. 2003 Apr 11;466(1-2):213-21.PMID: 12679159 [PubMed - indexed for MEDLINE]Related articles

Effect of 17beta-estradiol on insulin secretion and cytosolic calcium in Min6 mouse insulinoma cells and human islets of Langerhans.

Al-Majed HT, Squires PE, Persaud SJ, Huang GC, Amiel S, Whitehouse BJ, Jones PM.

Pancreas. 2005 May;30(4):307-13.PMID: 15841038 [PubMed - indexed for MEDLINE]Related articles

Wortmannin inhibits insulin secretion in pancreatic islets and beta-TC3 cells independent of its inhibition of phosphatidylinositol 3-kinase.

Gao Z, Konrad RJ, Collins H, Matschinsky FM, Rothenberg PL, Wolf BA.

Diabetes. 1996 Jul;45(7):854-62.PMID: 8666133 [PubMed - indexed for MEDLINE]Related articles

Pancreatic beta cell line MIN6 exhibits characteristics of glucose metabolism and glucose-stimulated insulin secretion similar to those of normal islets.

Ishihara H, Asano T, Tsukuda K, Katagiri H, Inukai K, Anai M, Kikuchi M, Yazaki Y, Miyazaki JI, Oka Y.

Diabetologia. 1993 Nov;36(11):1139-45.PMID: 8270128 [PubMed - indexed for MEDLINE]Related articles

Regulation of gene expression by glucose in pancreatic beta -cells (MIN6) via insulin secretion and activation of phosphatidylinositol 3'-kinase.

da Silva Xavier G, Varadi A, Ainscow EK, Rutter GA.

J Biol Chem. 2000 Nov 17;275(46):36269-77.PMID: 10967119 [PubMed - indexed for MEDLINE]Related articlesFree article

Tolbutamide and diazoxide modulate phospholipase C-linked Ca(2+) signaling and insulin secretion in beta-cells.

Schöfl C, Börger J, Mader T, Waring M, von zur Mühlen A, Brabant G.

Am J Physiol Endocrinol Metab. 2000 Apr;278(4):E639-47.PMID: 10751197 [PubMed - indexed for MEDLINE]Related articlesFree article

Inhibition of mitochondrial Na+-Ca2+ exchanger increases mitochondrial metabolism and potentiates glucose-stimulated insulin secretion in rat pancreatic islets.

Lee B, Miles PD, Vargas L, Luan P, Glasco S, Kushnareva Y, Kornbrust ES, Grako KA, Wollheim CB, Maechler P, Olefsky JM, Anderson CM.

Diabetes. 2003 Apr;52(4):965-73.PMID: 12663468 [PubMed - indexed for MEDLINE]Related articlesFree article

Glucose-regulated pulsatile insulin release from mouse islets via the K(ATP) channel-independent pathway.

Westerlund J, Ortsäter H, Palm F, Sundsten T, Bergsten P.

Eur J Endocrinol. 2001 Jun;144(6):667-75.PMID: 11375802 [PubMed - indexed for MEDLINE]Related articlesFree article

Glucose- and interleukin-1beta-induced beta-cell apoptosis requires Ca2+ influx and extracellular signal-regulated kinase (ERK) 1/2 activation and is prevented by a sulfonylurea receptor 1/inwardly rectifying K+ channel 6.2 (SUR/Kir6.2) selective potassium channel opener in human islets.

Maedler K, Størling J, Sturis J, Zuellig RA, Spinas GA, Arkhammar PO, Mandrup-Poulsen T, Donath MY.

Diabetes. 2004 Jul;53(7):1706-13.PMID: 15220194 [PubMed - indexed for MEDLINE]Related articlesFree article

Selective loss of glucose-induced amplification of insulin secretion in mouse pancreatic islets pretreated with sulfonylurea in the absence of fuels.

Urban KA, Panten U.

Diabetologia. 2005 Dec;48(12):2563-6. Epub 2005 Nov 11.PMID: 16283243 [PubMed - indexed for MEDLINE]Related articles

Direct regulation of insulin secretion by angiotensin II in human islets of Langerhans.

Ramracheya RD, Muller DS, Wu Y, Whitehouse BJ, Huang GC, Amiel SA, Karalliedde J, Viberti G, Jones PM, Persaud SJ.

Diabetologia. 2006 Feb;49(2):321-31. Epub 2006 Jan 17.PMID: 16416272 [PubMed - indexed for MEDLINE]Related articles

Glucokinase activator PSN-GK1 displays enhanced antihyperglycaemic and insulinotropic actions.

Fyfe MC, White JR, Taylor A, Chatfield R, Wargent E, Printz RL, Sulpice T, McCormack JG, Procter MJ, Reynet C, Widdowson PS, Wong-Kai-In P.

Diabetologia. 2007 Jun;50(6):1277-87. Epub 2007 Apr 6.PMID: 17415548 [PubMed - indexed for MEDLINE]Related articles

Distinct effect of diazoxide on insulin secretion stimulated by protein kinase A and protein kinase C in rat pancreatic islets.

Shen ZP, Nishimura M, Tsuura Y, Fujimoto S, Mukai E, Yamada Y, Seino Y.

Diabetes Res Clin Pract. 2001 Jul;53(1):9-16.PMID: 11378208 [PubMed - indexed for MEDLINE]Related articles

The atypical antipsychotic clozapine impairs insulin secretion by inhibiting glucose metabolism and distal steps in rat pancreatic islets.

Sasaki N, Iwase M, Uchizono Y, Nakamura U, Imoto H, Abe S, Iida M.

Diabetologia. 2006 Dec;49(12):2930-8. Epub 2006 Oct 27.PMID: 17072584 [PubMed - indexed for MEDLINE]Related articles

Differential mechanisms of glucose and palmitate in augmentation of insulin secretion in mouse pancreatic islets.

Thams P, Capito K.

Diabetologia. 2001 Jun;44(6):738-46.PMID: 11440367 [PubMed - indexed for MEDLINE]Related articles

Metabolic, cationic and secretory response to D-glucose in depolarized and Ca(2+)-deprived rat islets exposed to diazoxide.

Lebrun P, Antoine MH, Nguyen QA, Picton S, Malaisse WJ.

Cell Calcium. 2000 Apr;27(4):213-22.PMID: 10858667 [PubMed - indexed for MEDLINE]Related articles

Different signaling pathways involved in glucose- and cell swelling-induced insulin secretion by rat pancreatic islets in vitro.

Bacová Z, Benický J, Lukyanetz EE, Lukyanetz IA, Strbák V.

Cell Physiol Biochem. 2005;16(1-3):59-68.PMID: 16121034 [PubMed - indexed for MEDLINE]Related articles

Effect of the insulin mimetic L-783,281 on intracellular Ca2+ and insulin secretion from pancreatic beta-cells.

Roper MG, Qian WJ, Zhang BB, Kulkarni RN, Kahn CR, Kennedy RT.

Diabetes. 2002 Feb;51 Suppl 1:S43-9.PMID: 11815457 [PubMed - indexed for MEDLINE]Related articlesFree article