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    Results: 1 to 20 of 144

    1.

    A pilot study of IL-1 inhibition by anakinra in acute gout.

    So A, De Smedt T, Revaz S, Tschopp J.

    Arthritis Res Ther. 2007;9(2):R28.

    PMID:
    17352828
    [PubMed - indexed for MEDLINE]
    Free PMC Article
    2.

    Gout-associated uric acid crystals activate the NALP3 inflammasome.

    Martinon F, Pétrilli V, Mayor A, Tardivel A, Tschopp J.

    Nature. 2006 Mar 9;440(7081):237-41. Epub 2006 Jan 11.

    PMID:
    16407889
    [PubMed - indexed for MEDLINE]
    3.

    Plasma interleukin (IL)-18 (interferon-gamma-inducing factor) and other inflammatory cytokines in patients with gouty arthritis and monosodium urate monohydrate crystal-induced secretion of IL-18.

    Inokuchi T, Moriwaki Y, Tsutsui H, Yamamoto A, Takahashi S, Tsutsumi Z, Ka T, Nakanishi K, Yamamoto T.

    Cytokine. 2006 Jan 7;33(1):21-7. Epub 2006 Jan 5.

    PMID:
    16406656
    [PubMed - indexed for MEDLINE]
    4.

    Hyperalgesia, synovitis and multiple biomarkers of inflammation are suppressed by interleukin 1 inhibition in a novel animal model of gouty arthritis.

    Torres R, Macdonald L, Croll SD, Reinhardt J, Dore A, Stevens S, Hylton DM, Rudge JS, Liu-Bryan R, Terkeltaub RA, Yancopoulos GD, Murphy AJ.

    Ann Rheum Dis. 2009 Oct;68(10):1602-8. Epub 2009 Jun 14.

    PMID:
    19528034
    [PubMed - indexed for MEDLINE]
    5.

    Engagement of fatty acids with Toll-like receptor 2 drives interleukin-1β production via the ASC/caspase 1 pathway in monosodium urate monohydrate crystal-induced gouty arthritis.

    Joosten LA, Netea MG, Mylona E, Koenders MI, Malireddi RK, Oosting M, Stienstra R, van de Veerdonk FL, Stalenhoef AF, Giamarellos-Bourboulis EJ, Kanneganti TD, van der Meer JW.

    Arthritis Rheum. 2010 Nov;62(11):3237-48. doi: 10.1002/art.27667.

    PMID:
    20662061
    [PubMed - indexed for MEDLINE]
    Free PMC Article
    6.

    The inflammasome, autoinflammatory diseases, and gout.

    Pétrilli V, Martinon F.

    Joint Bone Spine. 2007 Dec;74(6):571-6. Epub 2007 Aug 21. Review.

    PMID:
    17714972
    [PubMed - indexed for MEDLINE]
    7.
    8.

    NALP3 inflammasome functional polymorphisms and gout susceptibility.

    Miao ZM, Zhao SH, Yan SL, Li CG, Wang YG, Meng DM, Zhou L, Mi QS.

    Cell Cycle. 2009 Jan 1;8(1):27-30. Epub 2009 Jan 31.

    PMID:
    19106604
    [PubMed - indexed for MEDLINE]
    Free Article
    9.

    Gene polymorphisms in the NALP3 inflammasome are associated with interleukin-1 production and severe inflammation: relation to common inflammatory diseases?

    Verma D, Lerm M, Blomgran Julinder R, Eriksson P, Söderkvist P, Särndahl E.

    Arthritis Rheum. 2008 Mar;58(3):888-94.

    PMID:
    18311798
    [PubMed - indexed for MEDLINE]
    Free Article
    10.

    Central role of complement membrane attack complex in monosodium urate crystal-induced neutrophilic rabbit knee synovitis.

    Tramontini N, Huber C, Liu-Bryan R, Terkeltaub RA, Kilgore KS.

    Arthritis Rheum. 2004 Aug;50(8):2633-9.

    PMID:
    15334478
    [PubMed - indexed for MEDLINE]
    Free Article
    11.

    Transglutaminase 2 limits murine peritoneal acute gout-like inflammation by regulating macrophage clearance of apoptotic neutrophils.

    Rose DM, Sydlaske AD, Agha-Babakhani A, Johnson K, Terkeltaub R.

    Arthritis Rheum. 2006 Oct;54(10):3363-71.

    PMID:
    17009310
    [PubMed - indexed for MEDLINE]
    Free Article
    12.

    Interleukin-1 inhibition by anakinra in refractory chronic tophaceous gout.

    Tran AP, Edelman J.

    Int J Rheum Dis. 2011 Aug;14(3):e33-7. doi: 10.1111/j.1756-185X.2011.01629.x.

    PMID:
    21816011
    [PubMed - indexed for MEDLINE]
    13.

    [New aspects of the pathogenesis of gout. Danger signals, autoinflammation and beyond].

    Lamprecht P, Till A, Kabelitz D.

    Z Rheumatol. 2008 Mar;67(2):151-6. Review. German.

    PMID:
    18299853
    [PubMed - indexed for MEDLINE]
    14.

    Antihyperalgesic effects induced by the IL-1 receptor antagonist anakinra and increased IL-1beta levels in inflamed and osteosarcoma-bearing mice.

    Baamonde A, Curto-Reyes V, Juárez L, Meana A, Hidalgo A, Menéndez L.

    Life Sci. 2007 Aug 2;81(8):673-82. Epub 2007 Jul 18.

    PMID:
    17692876
    [PubMed - indexed for MEDLINE]
    15.

    Difficult-to-treat gouty arthritis: a disease warranting better management.

    Schlesinger N.

    Drugs. 2011 Jul 30;71(11):1413-39. doi: 10.2165/11592290-000000000-00000. Review.

    PMID:
    21812506
    [PubMed - indexed for MEDLINE]
    16.

    Is IL-1 a good therapeutic target in the treatment of arthritis?

    Burger D, Dayer JM, Palmer G, Gabay C.

    Best Pract Res Clin Rheumatol. 2006 Oct;20(5):879-96. Review.

    PMID:
    16980212
    [PubMed - indexed for MEDLINE]
    17.

    [New knowledge on the pathophysiology and therapy of gout].

    So A.

    Z Rheumatol. 2007 Nov;66(7):562, 564-7. Review. German.

    PMID:
    17924125
    [PubMed - indexed for MEDLINE]
    18.

    Management of treatment resistant inflammation of acute on chronic tophaceous gout with anakinra.

    McGonagle D, Tan AL, Shankaranarayana S, Madden J, Emery P, McDermott MF.

    Ann Rheum Dis. 2007 Dec;66(12):1683-4. No abstract available.

    PMID:
    17998217
    [PubMed - indexed for MEDLINE]
    Free PMC Article
    19.

    Colchicine: its mechanism of action and efficacy in crystal-induced inflammation.

    Nuki G.

    Curr Rheumatol Rep. 2008 Jul;10(3):218-27. Review.

    PMID:
    18638431
    [PubMed - indexed for MEDLINE]
    20.

    Phenotype, genotype, and sustained response to anakinra in 22 patients with autoinflammatory disease associated with CIAS-1/NALP3 mutations.

    Leslie KS, Lachmann HJ, Bruning E, McGrath JA, Bybee A, Gallimore JR, Roberts PF, Woo P, Grattan CE, Hawkins PN.

    Arch Dermatol. 2006 Dec;142(12):1591-7.

    PMID:
    17178985
    [PubMed - indexed for MEDLINE]

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