PubMed

Lack of influence of GTP cyclohydrolase gene (GCH1) variations on pain sensitivity in humans.

Kim H, Dionne RA.

Mol Pain. 2007 Mar 7;3:6.PMID: 17343757 [PubMed - indexed for MEDLINE]Free PMC ArticleFree textRelated citations

Do genetic predictors of pain sensitivity associate with persistent widespread pain?

Holliday KL, Nicholl BI, Macfarlane GJ, Thomson W, Davies KA, McBeth J.

Mol Pain. 2009 Sep 23;5:56.PMID: 19775452 [PubMed - indexed for MEDLINE]Free PMC ArticleFree textRelated citations

Does the pain-protective GTP cyclohydrolase haplotype significantly alter the pattern or severity of pain in humans with chronic pancreatitis?

Lazarev M, Lamb J, Barmada MM, Dai F, Anderson MA, Max MB, Whitcomb DC.

Mol Pain. 2008 Nov 17;4:58.PMID: 19014702 [PubMed - indexed for MEDLINE]Free PMC ArticleFree textRelated citations

Reliable screening for a pain-protective haplotype in the GTP cyclohydrolase 1 gene (GCH1) through the use of 3 or fewer single nucleotide polymorphisms.

Lötsch J, Belfer I, Kirchhof A, Mishra BK, Max MB, Doehring A, Costigan M, Woolf CJ, Geisslinger G, Tegeder I.

Clin Chem. 2007 Jun;53(6):1010-5. Epub 2007 Mar 15.PMID: 17363416 [PubMed - indexed for MEDLINE]Free ArticleRelated citations

Polymorphisms in the GTP cyclohydrolase gene (GCH1) are associated with ratings of capsaicin pain.

Campbell CM, Edwards RR, Carmona C, Uhart M, Wand G, Carteret A, Kim YK, Frost J, Campbell JN.

Pain. 2009 Jan;141(1-2):114-8. Epub 2008 Dec 9.PMID: 19081190 [PubMed - indexed for MEDLINE]Free PMC ArticleFree textRelated citations

Cross-sectional assessment of the consequences of a GTP cyclohydrolase 1 haplotype for specialized tertiary outpatient pain care.

Doehring A, Freynhagen R, Griessinger N, Zimmermann M, Sittl R, Hentig N, Geisslinger G, Lötsch J.

Clin J Pain. 2009 Nov-Dec;25(9):781-5.PMID: 19851158 [PubMed - indexed for MEDLINE]Related citations

Reduced hyperalgesia in homozygous carriers of a GTP cyclohydrolase 1 haplotype.

Tegeder I, Adolph J, Schmidt H, Woolf CJ, Geisslinger G, Lötsch J.

Eur J Pain. 2008 Nov;12(8):1069-77. Epub 2008 Apr 18.PMID: 18374612 [PubMed - indexed for MEDLINE]Related citations

Genetic predictors for acute experimental cold and heat pain sensitivity in humans.

Kim H, Mittal DP, Iadarola MJ, Dionne RA.

J Med Genet. 2006 Aug;43(8):e40.PMID: 16882734 [PubMed - indexed for MEDLINE]Free PMC ArticleFree textRelated citations

A GTP cyclohydrolase 1 genetic variant delays cancer pain.

Lötsch J, Klepstad P, Doehring A, Dale O.

Pain. 2010 Jan;148(1):103-6. Epub 2009 Dec 2.PMID: 19959292 [PubMed - indexed for MEDLINE]Related citations

Clinical genetics of functionally mild non-coding GTP cyclohydrolase 1 (GCH1) polymorphisms modulating pain and cardiovascular risk.

Doehring A, Antoniades C, Channon KM, Tegeder I, Lötsch J.

Mutat Res. 2008 Sep-Oct;659(3):195-201. Epub 2008 Apr 26. Review.PMID: 18515178 [PubMed - indexed for MEDLINE]Related citations

A comprehensive analysis of common genetic variation in prolactin (PRL) and PRL receptor (PRLR) genes in relation to plasma prolactin levels and breast cancer risk: the multiethnic cohort.

Lee SA, Haiman CA, Burtt NP, Pooler LC, Cheng I, Kolonel LN, Pike MC, Altshuler D, Hirschhorn JN, Henderson BE, Stram DO.

BMC Med Genet. 2007 Dec 1;8:72.PMID: 18053149 [PubMed - indexed for MEDLINE]Free PMC ArticleFree textRelated citations

Genetic influence on variability in human acute experimental pain sensitivity associated with gender, ethnicity and psychological temperament.

Kim H, Neubert JK, San Miguel A, Xu K, Krishnaraju RK, Iadarola MJ, Goldman D, Dionne RA.

Pain. 2004 Jun;109(3):488-96.PMID: 15157710 [PubMed - indexed for MEDLINE]Related citations

Adaptive copy number evolution in malaria parasites.

Nair S, Miller B, Barends M, Jaidee A, Patel J, Mayxay M, Newton P, Nosten F, Ferdig MT, Anderson TJ.

PLoS Genet. 2008 Oct;4(10):e1000243. Epub 2008 Oct 31.PMID: 18974876 [PubMed - indexed for MEDLINE]Free PMC ArticleFree textRelated citations

The association between genetic variants in SORL1 and Alzheimer disease in an urban, multiethnic, community-based cohort.

Lee JH, Cheng R, Schupf N, Manly J, Lantigua R, Stern Y, Rogaeva E, Wakutani Y, Farrer L, St George-Hyslop P, Mayeux R.

Arch Neurol. 2007 Apr;64(4):501-6.PMID: 17420311 [PubMed - indexed for MEDLINE]Free PMC ArticleFree textRelated citations

GTP cyclohydrolase and tetrahydrobiopterin regulate pain sensitivity and persistence.

Tegeder I, Costigan M, Griffin RS, Abele A, Belfer I, Schmidt H, Ehnert C, Nejim J, Marian C, Scholz J, Wu T, Allchorne A, Diatchenko L, Binshtok AM, Goldman D, Adolph J, Sama S, Atlas SJ, Carlezon WA, Parsegian A, Lötsch J, Fillingim RB, Maixner W, Geisslinger G, Max MB, Woolf CJ.

Nat Med. 2006 Nov;12(11):1269-77. Epub 2006 Oct 22.PMID: 17057711 [PubMed - indexed for MEDLINE]Related citations

Genetic variation in the catechol-O-methyltransferase (COMT) gene and morphine requirements in cancer patients with pain.

Rakvåg TT, Ross JR, Sato H, Skorpen F, Kaasa S, Klepstad P.

Mol Pain. 2008 Dec 18;4:64.PMID: 19094200 [PubMed - indexed for MEDLINE]Free PMC ArticleFree textRelated citations

Comparison of linkage disequilibrium patterns and haplotype structure of eight single nucleotide polymorphisms across the CYP1A2 gene between the Korean, and other populations registered in the International HapMap database.

Woo SW, Kang TS, Park HJ, Lee JE, Roh J.

J Clin Pharm Ther. 2009 Aug;34(4):429-36.PMID: 19583676 [PubMed - indexed for MEDLINE]Related citations

[Genetic polymorphisms and human sensitivity to pain and opioids]

Nishizawa D, Nagashima M, Satoh Y, Tagami M, Ikeda K.

Masui. 2009 Sep;58(9):1093-101. Review. Japanese. PMID: 19764431 [PubMed - indexed for MEDLINE]Related citations

GCH1 haplotype determines vascular and plasma biopterin availability in coronary artery disease effects on vascular superoxide production and endothelial function.

Antoniades C, Shirodaria C, Van Assche T, Cunnington C, Tegeder I, Lötsch J, Guzik TJ, Leeson P, Diesch J, Tousoulis D, Stefanadis C, Costigan M, Woolf CJ, Alp NJ, Channon KM.

J Am Coll Cardiol. 2008 Jul 8;52(2):158-65.PMID: 18598896 [PubMed - indexed for MEDLINE]Free PMC ArticleFree textRelated citations

Effective relief of neuropathic pain by adeno-associated virus-mediated expression of a small hairpin RNA against GTP cyclohydrolase 1.

Kim SJ, Lee WI, Lee YS, Kim DH, Chang JW, Kim SW, Lee H.

Mol Pain. 2009 Nov 18;5:67.PMID: 19922668 [PubMed - indexed for MEDLINE]Free PMC ArticleFree textRelated citations