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    Results: 1 to 20 of 91

    1.

    Expression of PPARalpha modifies fatty acid effects on insulin secretion in uncoupling protein-2 knockout mice.

    Fatehi-Hassanabad Z, Chan CB.

    Nutr Metab (Lond). 2007 Mar 6;4:6.PMID: 17341307 [PubMed]Related articlesFree article

    2.

    Free fatty acid-induced beta-cell defects are dependent on uncoupling protein 2 expression.

    Joseph JW, Koshkin V, Saleh MC, Sivitz WI, Zhang CY, Lowell BB, Chan CB, Wheeler MB.

    J Biol Chem. 2004 Dec 3;279(49):51049-56. Epub 2004 Sep 23.PMID: 15448158 [PubMed - indexed for MEDLINE]Related articlesFree article

    3.

    Peroxisome proliferator-activated receptor alpha (PPARalpha) potentiates, whereas PPARgamma attenuates, glucose-stimulated insulin secretion in pancreatic beta-cells.

    Ravnskjaer K, Boergesen M, Rubi B, Larsen JK, Nielsen T, Fridriksson J, Maechler P, Mandrup S.

    Endocrinology. 2005 Aug;146(8):3266-76. Epub 2005 May 5.PMID: 15878969 [PubMed - indexed for MEDLINE]Related articlesFree article

    4.

    Peroxisome proliferator-activated receptor-alpha regulates the expression of pancreatic/duodenal homeobox-1 in rat insulinoma (INS-1) cells and ameliorates glucose-induced insulin secretion impaired by palmitate.

    Sun Y, Zhang L, Gu HF, Han W, Ren M, Wang F, Gong B, Wang L, Guo H, Xin W, Zhao J, Gao L.

    Endocrinology. 2008 Feb;149(2):662-71. Epub 2007 Nov 8.PMID: 17991720 [PubMed - indexed for MEDLINE]Related articlesFree article

    5.

    Endogenous islet uncoupling protein-2 expression and loss of glucose homeostasis in ob/ob mice.

    Saleh MC, Wheeler MB, Chan CB.

    J Endocrinol. 2006 Sep;190(3):659-67.PMID: 17003267 [PubMed - indexed for MEDLINE]Related articlesFree article

    6.

    Pancreatic islet adaptation to fasting is dependent on peroxisome proliferator-activated receptor alpha transcriptional up-regulation of fatty acid oxidation.

    Gremlich S, Nolan C, Roduit R, Burcelin R, Peyot ML, Delghingaro-Augusto V, Desvergne B, Michalik L, Prentki M, Wahli W.

    Endocrinology. 2005 Jan;146(1):375-82. Epub 2004 Sep 30.PMID: 15459119 [PubMed - indexed for MEDLINE]Related articlesFree article

    7.

    cAMP-mediated signaling normalizes glucose-stimulated insulin secretion in uncoupling protein-2 overexpressing beta-cells.

    McQuaid TS, Saleh MC, Joseph JW, Gyulkhandanyan A, Manning-Fox JE, MacLellan JD, Wheeler MB, Chan CB.

    J Endocrinol. 2006 Sep;190(3):669-80.PMID: 17003268 [PubMed - indexed for MEDLINE]Related articlesFree article

    8.

    Alteration of the malonyl-CoA/carnitine palmitoyltransferase I interaction in the beta-cell impairs glucose-induced insulin secretion.

    Herrero L, Rubí B, Sebastián D, Serra D, Asins G, Maechler P, Prentki M, Hegardt FG.

    Diabetes. 2005 Feb;54(2):462-71.PMID: 15677504 [PubMed - indexed for MEDLINE]Related articlesFree article

    9.

    PPARalpha suppresses insulin secretion and induces UCP2 in insulinoma cells.

    Tordjman K, Standley KN, Bernal-Mizrachi C, Leone TC, Coleman T, Kelly DP, Semenkovich CF.

    J Lipid Res. 2002 Jun;43(6):936-43.PMID: 12032169 [PubMed - indexed for MEDLINE]Related articlesFree article

    10.

    Interactive influences of peroxisome proliferator-activated receptor alpha activation and glucocorticoids on pancreatic beta cell compensation in insulin resistance induced by dietary saturated fat in the rat.

    Holness MJ, Smith ND, Greenwood GK, Sugden MC.

    Diabetologia. 2005 Oct;48(10):2062-8. Epub 2005 Aug 19.PMID: 16132960 [PubMed - indexed for MEDLINE]Related articles

    11.

    Plasma free fatty acids and peroxisome proliferator-activated receptor alpha in the control of myocardial uncoupling protein levels.

    Murray AJ, Panagia M, Hauton D, Gibbons GF, Clarke K.

    Diabetes. 2005 Dec;54(12):3496-502.PMID: 16306367 [PubMed - indexed for MEDLINE]Related articlesFree article

    12.

    Peroxisome proliferator-activated receptor alpha improves pancreatic adaptation to insulin resistance in obese mice and reduces lipotoxicity in human islets.

    Lalloyer F, Vandewalle B, Percevault F, Torpier G, Kerr-Conte J, Oosterveer M, Paumelle R, Fruchart JC, Kuipers F, Pattou F, Fiévet C, Staels B.

    Diabetes. 2006 Jun;55(6):1605-13.PMID: 16731822 [PubMed - indexed for MEDLINE]Related articlesFree article

    13.

    Peroxisome proliferator-activated receptor-alpha activation during pregnancy attenuates glucose-stimulated insulin hypersecretion in vivo by increasing insulin sensitivity, without impairing pregnancy-induced increases in beta-cell glucose sensing and responsiveness.

    Sugden MC, Greenwood GK, Smith ND, Holness MJ.

    Endocrinology. 2003 Jan;144(1):146-53.PMID: 12488340 [PubMed - indexed for MEDLINE]Related articlesFree article

    14.

    Pancreatic islet response to hyperglycemia is dependent on peroxisome proliferator-activated receptor alpha (PPARalpha).

    Bihan H, Rouault C, Reach G, Poitout V, Staels B, Guerre-Millo M.

    FEBS Lett. 2005 Apr 25;579(11):2284-8.PMID: 15848159 [PubMed - indexed for MEDLINE]Related articles

    15.

    Peroxisome proliferator-activated receptor-alpha and glucocorticoids interactively regulate insulin secretion during pregnancy.

    Holness MJ, Greenwood GK, Smith ND, Sugden MC.

    Diabetes. 2006 Dec;55(12):3501-8.PMID: 17130498 [PubMed - indexed for MEDLINE]Related articlesFree article

    16.

    Peroxisome proliferator-activated receptor-alpha deficiency protects aged mice from insulin resistance induced by high-fat diet.

    Cha DR, Han JY, Su DM, Zhang Y, Fan X, Breyer MD, Guan Y.

    Am J Nephrol. 2007;27(5):479-82. Epub 2007 Jul 25.PMID: 17652964 [PubMed - indexed for MEDLINE]Related articles

    17.

    Durable islet effects on insulin secretion and protein kinase A expression following exendin-4 treatment of high-fat diet-fed mice.

    Winzell MS, Ahrén B.

    J Mol Endocrinol. 2008 Feb;40(2):93-100.PMID: 18234911 [PubMed - indexed for MEDLINE]Related articlesFree article

    18.

    Regulation of hormone-sensitive lipase in islets.

    Shen WJ, Liang Y, Wang J, Harada K, Patel S, Michie SA, Osuga J, Ishibashi S, Kraemer FB.

    Diabetes Res Clin Pract. 2007 Jan;75(1):14-26. Epub 2006 Jun 9.PMID: 16765472 [PubMed - indexed for MEDLINE]Related articles

    19.

    PPARalpha-mediated effects of dietary lipids on intestinal barrier gene expression.

    de Vogel-van den Bosch HM, Bünger M, de Groot PJ, Bosch-Vermeulen H, Hooiveld GJ, Müller M.

    BMC Genomics. 2008 May 19;9:231.PMID: 18489776 [PubMed - indexed for MEDLINE]Related articlesFree article

    20.

    Re-evaluation of fatty acid metabolism-related gene expression in nonalcoholic fatty liver disease.

    Kohjima M, Enjoji M, Higuchi N, Kato M, Kotoh K, Yoshimoto T, Fujino T, Yada M, Yada R, Harada N, Takayanagi R, Nakamuta M.

    Int J Mol Med. 2007 Sep;20(3):351-8.PMID: 17671740 [PubMed - indexed for MEDLINE]Related articles

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