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Formation of multinucleated giant cells and microglial degeneration in rats expressing a mutant Cu/Zn superoxide dismutase gene.

Fendrick SE, Xue QS, Streit WJ.

J Neuroinflammation. 2007 Feb 28;4:9.PMID: 17328801 [PubMed - indexed for MEDLINE]Related articlesFree article

Focal loss of the glutamate transporter EAAT2 in a transgenic rat model of SOD1 mutant-mediated amyotrophic lateral sclerosis (ALS).

Howland DS, Liu J, She Y, Goad B, Maragakis NJ, Kim B, Erickson J, Kulik J, DeVito L, Psaltis G, DeGennaro LJ, Cleveland DW, Rothstein JD.

Proc Natl Acad Sci U S A. 2002 Feb 5;99(3):1604-9. Epub 2002 Jan 29.PMID: 11818550 [PubMed - indexed for MEDLINE]Related articlesFree article

Ablation of proliferating microglia does not affect motor neuron degeneration in amyotrophic lateral sclerosis caused by mutant superoxide dismutase.

Gowing G, Philips T, Van Wijmeersch B, Audet JN, Dewil M, Van Den Bosch L, Billiau AD, Robberecht W, Julien JP.

J Neurosci. 2008 Oct 8;28(41):10234-44.PMID: 18842883 [PubMed - indexed for MEDLINE]Related articlesFree article

Progressive changes in microglia and macrophages in spinal cord and peripheral nerve in the transgenic rat model of amyotrophic lateral sclerosis.

Graber DJ, Hickey WF, Harris BT.

J Neuroinflammation. 2010 Jan 28;7:8.PMID: 20109233 [PubMed - in process]Related articlesFree article

The proinflammatory action of microglial P2 receptors is enhanced in SOD1 models for amyotrophic lateral sclerosis.

D'Ambrosi N, Finocchi P, Apolloni S, Cozzolino M, Ferri A, Padovano V, Pietrini G, Carrì MT, Volonté C.

J Immunol. 2009 Oct 1;183(7):4648-56. Epub 2009 Sep 4.PMID: 19734218 [PubMed - indexed for MEDLINE]Related articles

Impaired spinal cord glutamate transport capacity and reduced sensitivity to riluzole in a transgenic superoxide dismutase mutant rat model of amyotrophic lateral sclerosis.

Dunlop J, Beal McIlvain H, She Y, Howland DS.

J Neurosci. 2003 Mar 1;23(5):1688-96.PMID: 12629173 [PubMed - indexed for MEDLINE]Related articlesFree article

Activation and response to axotomy of microglia in the facial motor nuclei of G93A superoxide dismutase transgenic mice.

Mariotti R, Bentivoglio M.

Neurosci Lett. 2000 May 12;285(2):87-90.PMID: 10793233 [PubMed - indexed for MEDLINE]Related articles

Activated protein C therapy slows ALS-like disease in mice by transcriptionally inhibiting SOD1 in motor neurons and microglia cells.

Zhong Z, Ilieva H, Hallagan L, Bell R, Singh I, Paquette N, Thiyagarajan M, Deane R, Fernandez JA, Lane S, Zlokovic AB, Liu T, Griffin JH, Chow N, Castellino FJ, Stojanovic K, Cleveland DW, Zlokovic BV.

J Clin Invest. 2009 Nov;119(11):3437-49. doi: 10.1172/JCI38476. Epub 2009 Oct 19.PMID: 19841542 [PubMed - indexed for MEDLINE]Related articlesFree article

Minocycline slows disease progression in a mouse model of amyotrophic lateral sclerosis.

Kriz J, Nguyen MD, Julien JP.

Neurobiol Dis. 2002 Aug;10(3):268-78.PMID: 12270689 [PubMed - indexed for MEDLINE]Related articles

Retinoid receptors in chronic degeneration of the spinal cord: observations in a rat model of amyotrophic lateral sclerosis.

Jokic N, Ling YY, Ward RE, Michael-Titus AT, Priestley JV, Malaspina A.

J Neurochem. 2007 Dec;103(5):1821-33. Epub 2007 Sep 13.PMID: 17956549 [PubMed - indexed for MEDLINE]Related articles

Functional alterations of the ubiquitin-proteasome system in motor neurons of a mouse model of familial amyotrophic lateral sclerosis.

Cheroni C, Marino M, Tortarolo M, Veglianese P, De Biasi S, Fontana E, Zuccarello LV, Maynard CJ, Dantuma NP, Bendotti C.

Hum Mol Genet. 2009 Jan 1;18(1):82-96. Epub 2008 Sep 29.PMID: 18826962 [PubMed - indexed for MEDLINE]Related articlesFree article

Motor neuron disease in transgenic mice with an H46R mutant SOD1 gene.

Sasaki S, Nagai M, Aoki M, Komori T, Itoyama Y, Iwata M.

J Neuropathol Exp Neurol. 2007 Jun;66(6):517-24.PMID: 17549011 [PubMed - indexed for MEDLINE]Related articles

Ultrastructural study of mitochondria in the spinal cord of transgenic mice with a G93A mutant SOD1 gene.

Sasaki S, Warita H, Murakami T, Abe K, Iwata M.

Acta Neuropathol. 2004 May;107(5):461-74. Epub 2004 Mar 17.PMID: 15029445 [PubMed - indexed for MEDLINE]Related articles

Cytosolic phospholipase A2 is induced in reactive glia following different forms of neurodegeneration.

Stephenson D, Rash K, Smalstig B, Roberts E, Johnstone E, Sharp J, Panetta J, Little S, Kramer R, Clemens J.

Glia. 1999 Aug;27(2):110-28.PMID: 10417811 [PubMed - indexed for MEDLINE]Related articles

Comparative analysis of the time-dependent functional and molecular changes in spinal cord degeneration induced by the G93A SOD1 gene mutation and by mechanical compression.

Malaspina A, Jokic N, Huang WL, Priestley JV.

BMC Genomics. 2008 Oct 23;9:500.PMID: 18947433 [PubMed - indexed for MEDLINE]Related articlesFree article

Role of matrix metalloproteinase-9 in a mouse model for amyotrophic lateral sclerosis.

Dewil M, Schurmans C, Starckx S, Opdenakker G, Van Den Bosch L, Robberecht W.

Neuroreport. 2005 Mar 15;16(4):321-4.PMID: 15729130 [PubMed - indexed for MEDLINE]Related articles

Accumulation of human SOD1 and ubiquitinated deposits in the spinal cord of SOD1G93A mice during motor neuron disease progression correlates with a decrease of proteasome.

Cheroni C, Peviani M, Cascio P, Debiasi S, Monti C, Bendotti C.

Neurobiol Dis. 2005 Apr;18(3):509-22.PMID: 15755678 [PubMed - indexed for MEDLINE]Related articles

Ultrastructural changes in lumbar spinal cord in transgenic SOD1G93A rats.

Fidziańska A, Gadomski R, Rafałowska J, Chrzanowska H, Grieb P.

Folia Neuropathol. 2006;44(3):175-82.PMID: 17039412 [PubMed - indexed for MEDLINE]Related articlesFree article

A dopamine receptor antagonist L-745,870 suppresses microglia activation in spinal cord and mitigates the progression in ALS model mice.

Tanaka K, Okada Y, Kanno T, Otomo A, Yanagisawa Y, Shouguchi-Miyata J, Suga E, Kohiki E, Onoe K, Osuga H, Aoki M, Hadano S, Itoyama Y, Ikeda JE.

Exp Neurol. 2008 Jun;211(2):378-86. Epub 2008 Mar 4.PMID: 18423451 [PubMed - indexed for MEDLINE]Related articles

Transcriptional profile of primary astrocytes expressing ALS-linked mutant SOD1.

Vargas MR, Pehar M, Díaz-Amarilla PJ, Beckman JS, Barbeito L.

J Neurosci Res. 2008 Dec;86(16):3515-25.PMID: 18683239 [PubMed - indexed for MEDLINE]Related articles