PubMed

To be or not to be protease activated receptor-1 in activated protein C-initiated endothelial barrier protection?

Li SS.

Crit Care. 2007;11(1):407; author reply 407. No abstract available. PMID: 17328792 [PubMed - indexed for MEDLINE]Related articlesFree article

Endothelial barrier protection by activated protein C through PAR1-dependent sphingosine 1-phosphate receptor-1 crossactivation.

Feistritzer C, Riewald M.

Blood. 2005 Apr 15;105(8):3178-84. Epub 2004 Dec 30.PMID: 15626732 [PubMed - indexed for MEDLINE]Related articlesFree article

Protease activated receptor 1 (PAR-1) activation by thrombin is protective in human pulmonary artery endothelial cells if endothelial protein C receptor is occupied by its natural ligand.

Bae JS, Rezaie AR.

Thromb Haemost. 2008 Jul;100(1):101-9.PMID: 18612544 [PubMed - indexed for MEDLINE]Related articlesFree article

Identification of a specific exosite on activated protein C for interaction with protease-activated receptor 1.

Yang L, Bae JS, Manithody C, Rezaie AR.

J Biol Chem. 2007 Aug 31;282(35):25493-500. Epub 2007 Jun 19.PMID: 17580306 [PubMed - indexed for MEDLINE]Related articlesFree article

The ligand occupancy of endothelial protein C receptor switches the protease-activated receptor 1-dependent signaling specificity of thrombin from a permeability-enhancing to a barrier-protective response in endothelial cells.

Bae JS, Yang L, Manithody C, Rezaie AR.

Blood. 2007 Dec 1;110(12):3909-16. Epub 2007 Sep 6.PMID: 17823308 [PubMed - indexed for MEDLINE]Related articlesFree article

Caveolae are required for protease-selective signaling by protease-activated receptor-1.

Russo A, Soh UJ, Paing MM, Arora P, Trejo J.

Proc Natl Acad Sci U S A. 2009 Apr 14;106(15):6393-7. Epub 2009 Mar 30.PMID: 19332793 [PubMed - indexed for MEDLINE]Related articlesFree article

Microparticle-associated endothelial protein C receptor and the induction of cytoprotective and anti-inflammatory effects.

Pérez-Casal M, Downey C, Cutillas-Moreno B, Zuzel M, Fukudome K, Toh CH.

Haematologica. 2009 Mar;94(3):387-94. Epub 2009 Feb 11.PMID: 19211643 [PubMed - indexed for MEDLINE]Related articlesFree article

Activated protein C-cleaved protease activated receptor-1 is retained on the endothelial cell surface even in the presence of thrombin.

Schuepbach RA, Feistritzer C, Brass LF, Riewald M.

Blood. 2008 Mar 1;111(5):2667-73. Epub 2007 Dec 18.PMID: 18089851 [PubMed - indexed for MEDLINE]Related articlesFree article

Protection of vascular barrier integrity by activated protein C in murine models depends on protease-activated receptor-1.

Schuepbach RA, Feistritzer C, Fernández JA, Griffin JH, Riewald M.

Thromb Haemost. 2009 Apr;101(4):724-33.PMID: 19350118 [PubMed - indexed for MEDLINE]Related articlesFree article

Activated protein C decreases tumor necrosis factor related apoptosis-inducing ligand by an EPCR- independent mechanism involving Egr-1/Erk-1/2 activation.

O'Brien LA, Richardson MA, Mehrbod SF, Berg DT, Gerlitz B, Gupta A, Grinnell BW.

Arterioscler Thromb Vasc Biol. 2007 Dec;27(12):2634-41. Epub 2007 Oct 11.PMID: 17932312 [PubMed - indexed for MEDLINE]Related articlesFree article

Activation of sphingosine kinase-1 reverses the increase in lung vascular permeability through sphingosine-1-phosphate receptor signaling in endothelial cells.

Tauseef M, Kini V, Knezevic N, Brannan M, Ramchandaran R, Fyrst H, Saba J, Vogel SM, Malik AB, Mehta D.

Circ Res. 2008 Nov 7;103(10):1164-72. Epub 2008 Oct 10.PMID: 18849324 [PubMed - indexed for MEDLINE]Related articlesFree article

Is APC activation of endothelial cell PAR1 important in severe sepsis?: Yes.

Ruf W.

J Thromb Haemost. 2005 Sep;3(9):1912-4. No abstract available. PMID: 16102094 [PubMed - indexed for MEDLINE]Related articles

Is APC activation of endothelial cell PAR1 important in severe sepsis?: No.

Esmon CT.

J Thromb Haemost. 2005 Sep;3(9):1910-1. No abstract available. PMID: 16102093 [PubMed - indexed for MEDLINE]Related articles

Lipid raft localization regulates the cleavage specificity of protease activated receptor 1 in endothelial cells.

Bae JS, Yang L, Rezaie AR.

J Thromb Haemost. 2008 Jun;6(6):954-61. Epub 2008 Feb 12.PMID: 18284602 [PubMed - indexed for MEDLINE]Related articles

Modification of the cytoprotective protein C pathway during Dengue virus infection of human endothelial vascular cells.

Cabello-Gutiérrez C, Manjarrez-Zavala ME, Huerta-Zepeda A, Cime-Castillo J, Monroy-Martínez V, Correa BB, Ruiz-Ordaz BH.

Thromb Haemost. 2009 May;101(5):916-28.PMID: 19404546 [PubMed - indexed for MEDLINE]Related articles

Dendritic cell PAR1-S1P3 signalling couples coagulation and inflammation.

Niessen F, Schaffner F, Furlan-Freguia C, Pawlinski R, Bhattacharjee G, Chun J, Derian CK, Andrade-Gordon P, Rosen H, Ruf W.

Nature. 2008 Apr 3;452(7187):654-8. Epub 2008 Feb 27.PMID: 18305483 [PubMed - indexed for MEDLINE]Related articles

Cytoprotective effect of activated protein C: specificity of PAR-1 signaling.

Crawley JT, Efthymiou M.

J Thromb Haemost. 2008 Jun;6(6):951-3. Epub 2008 Mar 21. No abstract available. PMID: 18363817 [PubMed - indexed for MEDLINE]Related articles

Functional responses of bone cells to thrombin.

Pagel CN, Sivagurunathan S, Loh LH, Tudor EM, Pike RN, Mackie EJ.

Biol Chem. 2006 Aug;387(8):1037-41. Review.PMID: 16895473 [PubMed - indexed for MEDLINE]Related articles

Dissociation of activated protein C functions by elimination of protein S cofactor enhancement.

Harmon S, Preston RJ, Ainle FN, Johnson JA, Cunningham MS, Smith OP, White B, O'Donnell JS.

J Biol Chem. 2008 Nov 7;283(45):30531-9. Epub 2008 Sep 8.PMID: 18779332 [PubMed - indexed for MEDLINE]Related articlesFree article

Endogenous EPCR/aPC-PAR1 signaling prevents inflammation-induced vascular leakage and lethality.

Niessen F, Furlan-Freguia C, Fernández JA, Mosnier LO, Castellino FJ, Weiler H, Rosen H, Griffin JH, Ruf W.

Blood. 2009 Mar 19;113(12):2859-66. Epub 2009 Jan 13.PMID: 19141861 [PubMed - indexed for MEDLINE]Related articles