PubMed

To be or not to be protease activated receptor-1 in activated protein C-initiated endothelial barrier protection?

Li SS.

Crit Care. 2007;11(1):407; author reply 407. No abstract available. PMID: 17328792 [PubMed - indexed for MEDLINE]Related articlesFree article

Endothelial barrier protection by activated protein C through PAR1-dependent sphingosine 1-phosphate receptor-1 crossactivation.

Feistritzer C, Riewald M.

Blood. 2005 Apr 15;105(8):3178-84. Epub 2004 Dec 30.PMID: 15626732 [PubMed - indexed for MEDLINE]Related articlesFree article

Activated protein C alters cytosolic calcium flux in human brain endothelium via binding to endothelial protein C receptor and activation of protease activated receptor-1.

Dömötör E, Benzakour O, Griffin JH, Yule D, Fukudome K, Zlokovic BV.

Blood. 2003 Jun 15;101(12):4797-801. Epub 2003 Feb 13.PMID: 12586611 [PubMed - indexed for MEDLINE]Related articlesFree article

Identification of a specific exosite on activated protein C for interaction with protease-activated receptor 1.

Yang L, Bae JS, Manithody C, Rezaie AR.

J Biol Chem. 2007 Aug 31;282(35):25493-500. Epub 2007 Jun 19.PMID: 17580306 [PubMed - indexed for MEDLINE]Related articlesFree article

Receptors of the protein C activation and activated protein C signaling pathways are colocalized in lipid rafts of endothelial cells.

Bae JS, Yang L, Rezaie AR.

Proc Natl Acad Sci U S A. 2007 Feb 20;104(8):2867-72. Epub 2007 Feb 13.PMID: 17299037 [PubMed - indexed for MEDLINE]Related articlesFree article

Activated protein C decreases tumor necrosis factor related apoptosis-inducing ligand by an EPCR- independent mechanism involving Egr-1/Erk-1/2 activation.

O'Brien LA, Richardson MA, Mehrbod SF, Berg DT, Gerlitz B, Gupta A, Grinnell BW.

Arterioscler Thromb Vasc Biol. 2007 Dec;27(12):2634-41. Epub 2007 Oct 11.PMID: 17932312 [PubMed - indexed for MEDLINE]Related articlesFree article

Is APC activation of endothelial cell PAR1 important in severe sepsis?: Yes.

Ruf W.

J Thromb Haemost. 2005 Sep;3(9):1912-4. No abstract available. PMID: 16102094 [PubMed - indexed for MEDLINE]Related articles

Is APC activation of endothelial cell PAR1 important in severe sepsis?: No.

Esmon CT.

J Thromb Haemost. 2005 Sep;3(9):1910-1. No abstract available. PMID: 16102093 [PubMed - indexed for MEDLINE]Related articles

Lipid raft localization regulates the cleavage specificity of protease activated receptor 1 in endothelial cells.

Bae JS, Yang L, Rezaie AR.

J Thromb Haemost. 2008 Jun;6(6):954-61. Epub 2008 Feb 12.PMID: 18284602 [PubMed - indexed for MEDLINE]Related articles

Dendritic cell PAR1-S1P3 signalling couples coagulation and inflammation.

Niessen F, Schaffner F, Furlan-Freguia C, Pawlinski R, Bhattacharjee G, Chun J, Derian CK, Andrade-Gordon P, Rosen H, Ruf W.

Nature. 2008 Apr 3;452(7187):654-8. Epub 2008 Feb 27.PMID: 18305483 [PubMed - indexed for MEDLINE]Related articles

Cytoprotective effect of activated protein C: specificity of PAR-1 signaling.

Crawley JT, Efthymiou M.

J Thromb Haemost. 2008 Jun;6(6):951-3. Epub 2008 Mar 21. No abstract available. PMID: 18363817 [PubMed - indexed for MEDLINE]Related articles

Functional responses of bone cells to thrombin.

Pagel CN, Sivagurunathan S, Loh LH, Tudor EM, Pike RN, Mackie EJ.

Biol Chem. 2006 Aug;387(8):1037-41. Review.PMID: 16895473 [PubMed - indexed for MEDLINE]Related articles

Endotoxemia and sepsis mortality reduction by non-anticoagulant activated protein C.

Kerschen EJ, Fernandez JA, Cooley BC, Yang XV, Sood R, Mosnier LO, Castellino FJ, Mackman N, Griffin JH, Weiler H.

J Exp Med. 2007 Oct 1;204(10):2439-48. Epub 2007 Sep 24.PMID: 17893198 [PubMed - indexed for MEDLINE]Related articlesFree article

Recombinant activated protein C in sepsis: endothelium protection or endothelium therapy?

Regnault V, Levy B.

Crit Care. 2007;11(1):103. Review.PMID: 17224039 [PubMed - indexed for MEDLINE]Related articlesFree article

Activated protein C in sepsis.

Taylor FB, Kinasewitz G.

J Thromb Haemost. 2004 May;2(5):708-17. Review. No abstract available. PMID: 15099275 [PubMed - indexed for MEDLINE]Related articles

Tissue factor induction by protease-activated receptor 1 requires intact caveolin-enriched membrane microdomains in human endothelial cells.

Banfi C, Brioschi M, Barcella S, Pignieri A, Parolari A, Biglioli P, Tremoli E, Mussoni L.

J Thromb Haemost. 2007 Dec;5(12):2437-44. Epub 2007 Sep 10.PMID: 17848177 [PubMed - indexed for MEDLINE]Related articles

Kallikrein-related peptidase 4 (KLK4) initiates intracellular signaling via protease-activated receptors (PARs). KLK4 and PAR-2 are co-expressed during prostate cancer progression.

Ramsay AJ, Dong Y, Hunt ML, Linn M, Samaratunga H, Clements JA, Hooper JD.

J Biol Chem. 2008 May 2;283(18):12293-304. Epub 2008 Feb 28.PMID: 18308730 [PubMed - indexed for MEDLINE]Related articlesFree article

'Role reversal' for the receptor PAR1 in sepsis-induced vascular damage.

Kaneider NC, Leger AJ, Agarwal A, Nguyen N, Perides G, Derian C, Covic L, Kuliopulos A.

Nat Immunol. 2007 Dec;8(12):1303-12. Epub 2007 Oct 28.PMID: 17965715 [PubMed - indexed for MEDLINE]Related articles

Dual regulation of endothelial junctional permeability.

Komarova YA, Mehta D, Malik AB.

Sci STKE. 2007 Nov 13;2007(412):re8. Review.PMID: 18000237 [PubMed - indexed for MEDLINE]Related articles

Activated protein C up-regulates IL-10 and inhibits tissue factor in blood monocytes.

Toltl LJ, Beaudin S, Liaw PC; Canadian Critical Care Translational Biology Group.

J Immunol. 2008 Aug 1;181(3):2165-73.PMID: 18641355 [PubMed - indexed for MEDLINE]Related articlesFree article