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Rapid turnover of phosphatidylinositol-4,5-bisphosphate in insulin-secreting cells mediated by Ca2+ and the ATP-to-ADP ratio.

Thore S, Wuttke A, Tengholm A.

Diabetes. 2007 Mar;56(3):818-26.PMID: 17327453 [PubMed - indexed for MEDLINE]Related articlesFree article

Glucose and insulin synergistically activate phosphatidylinositol 3-kinase to trigger oscillations of phosphatidylinositol 3,4,5-trisphosphate in beta-cells.

Hagren OI, Tengholm A.

J Biol Chem. 2006 Dec 22;281(51):39121-7. Epub 2006 Oct 30.PMID: 17074763 [PubMed - indexed for MEDLINE]Related articlesFree article

Feedback activation of phospholipase C via intracellular mobilization and store-operated influx of Ca2+ in insulin-secreting beta-cells.

Thore S, Dyachok O, Gylfe E, Tengholm A.

J Cell Sci. 2005 Oct 1;118(Pt 19):4463-71. Epub 2005 Sep 13.PMID: 16159958 [PubMed - indexed for MEDLINE]Related articlesFree article

Adenine nucleotide regulation in pancreatic beta-cells: modeling of ATP/ADP-Ca2+ interactions.

Fridlyand LE, Ma L, Philipson LH.

Am J Physiol Endocrinol Metab. 2005 Nov;289(5):E839-48. Epub 2005 Jun 28.PMID: 15985450 [PubMed - indexed for MEDLINE]Related articlesFree article

Oscillations of phospholipase C activity triggered by depolarization and Ca2+ influx in insulin-secreting cells.

Thore S, Dyachok O, Tengholm A.

J Biol Chem. 2004 May 7;279(19):19396-400. Epub 2004 Mar 25.PMID: 15044448 [PubMed - indexed for MEDLINE]Related articlesFree article

Interplay between cytoplasmic Ca2+ and the ATP/ADP ratio: a feedback control mechanism in mouse pancreatic islets.

Detimary P, Gilon P, Henquin JC.

Biochem J. 1998 Jul 15;333 ( Pt 2):269-74.PMID: 9657965 [PubMed - indexed for MEDLINE]Related articlesFree article

Temporal patterns of changes in ATP/ADP ratio, glucose 6-phosphate and cytoplasmic free Ca2+ in glucose-stimulated pancreatic beta-cells.

Nilsson T, Schultz V, Berggren PO, Corkey BE, Tornheim K.

Biochem J. 1996 Feb 15;314 ( Pt 1):91-4.PMID: 8660314 [PubMed - indexed for MEDLINE]Related articlesFree article

Hexosamine biosynthesis pathway flux contributes to insulin resistance via altering membrane phosphatidylinositol 4,5-bisphosphate and cortical filamentous actin.

Bhonagiri P, Pattar GR, Horvath EM, Habegger KM, McCarthy AM, Elmendorf JS.

Endocrinology. 2009 Apr;150(4):1636-45. Epub 2008 Nov 26.PMID: 19036880 [PubMed - indexed for MEDLINE]Related articles

Metabolic and ionic coupling factors in amino acid-stimulated insulin release in pancreatic beta-HC9 cells.

Doliba NM, Wehrli SL, Vatamaniuk MZ, Qin W, Buettger CW, Collins HW, Matschinsky FM.

Am J Physiol Endocrinol Metab. 2007 Jun;292(6):E1507-19. Epub 2007 Jan 30.PMID: 17264232 [PubMed - indexed for MEDLINE]Related articlesFree article

Mathematical simulation of membrane processes and metabolic fluxes of the pancreatic beta-cell.

Diederichs F.

Bull Math Biol. 2006 Oct;68(7):1779-818. Epub 2006 Jul 11.PMID: 16832733 [PubMed - indexed for MEDLINE]Related articles

Role of type Ialpha phosphatidylinositol-4-phosphate 5-kinase in insulin secretion, glucose metabolism, and membrane potential in INS-1 beta-cells.

Zhang J, Luo R, Wu H, Wei S, Han W, Li G.

Endocrinology. 2009 May;150(5):2127-35. Epub 2008 Dec 30.PMID: 19116346 [PubMed - indexed for MEDLINE]Related articles

Alpha-latrotoxin induces exocytosis by inhibition of voltage-dependent K+ channels and by stimulation of L-type Ca2+ channels via latrophilin in beta-cells.

Lajus S, Vacher P, Huber D, Dubois M, Benassy MN, Ushkaryov Y, Lang J.

J Biol Chem. 2006 Mar 3;281(9):5522-31. Epub 2005 Nov 21.PMID: 16301314 [PubMed - indexed for MEDLINE]Related articlesFree article

Glucose-induced metabolic oscillations parallel those of Ca(2+) and insulin release in clonal insulin-secreting cells. A multiwell approach to oscillatory cell behavior.

Deeney JT, Köhler M, Kubik K, Brown G, Schultz V, Tornheim K, Corkey BE, Berggren PO.

J Biol Chem. 2001 Oct 5;276(40):36946-50. Epub 2001 Jul 31.PMID: 11481328 [PubMed - indexed for MEDLINE]Related articlesFree article

Angiotensin II inhibits native bTREK-1 K+ channels through a PLC-, kinase C-, and PIP2-independent pathway requiring ATP hydrolysis.

Liu H, Enyeart JA, Enyeart JJ.

Am J Physiol Cell Physiol. 2007 Aug;293(2):C682-95. Epub 2007 May 9.PMID: 17494631 [PubMed - indexed for MEDLINE]Related articlesFree article

Uncoupling by (--)-epigallocatechin-3-gallate of ATP-sensitive potassium channels from phosphatidylinositol polyphosphates and ATP.

Jin JY, Park SH, Bae JH, Cho HC, Lim JG, Park WS, Han J, Lee JH, Song DK.

Pharmacol Res. 2007 Sep;56(3):237-47. Epub 2007 Jun 21.PMID: 17656102 [PubMed - indexed for MEDLINE]Related articles

Glucose stimulates Ca2+ influx and insulin secretion in 2-week-old beta-cells lacking ATP-sensitive K+ channels.

Szollosi A, Nenquin M, Aguilar-Bryan L, Bryan J, Henquin JC.

J Biol Chem. 2007 Jan 19;282(3):1747-56. Epub 2006 Nov 30.PMID: 17138557 [PubMed - indexed for MEDLINE]Related articlesFree article

Increasing uncoupling protein-2 in pancreatic beta cells does not alter glucose-induced insulin secretion but decreases production of reactive oxygen species.

Produit-Zengaffinen N, Davis-Lameloise N, Perreten H, Bécard D, Gjinovci A, Keller PA, Wollheim CB, Herrera P, Muzzin P, Assimacopoulos-Jeannet F.

Diabetologia. 2007 Jan;50(1):84-93. Epub 2006 Nov 28.PMID: 17131143 [PubMed - indexed for MEDLINE]Related articles

Intracellular ADP activates K+ channels that are inhibited by ATP in an insulin-secreting cell line.

Dunne MJ, Petersen OH.

FEBS Lett. 1986 Nov 10;208(1):59-62.PMID: 2429868 [PubMed - indexed for MEDLINE]Related articles

Dihydroxyacetone-induced oscillations in cytoplasmic free Ca2+ and the ATP/ADP ratio in pancreatic beta-cells at substimulatory glucose.

Juntti-Berggren L, Webb DL, Arkhammar PO, Schultz V, Schweda EK, Tornheim K, Berggren PO.

J Biol Chem. 2003 Oct 17;278(42):40710-6. Epub 2003 Aug 12.PMID: 12917415 [PubMed - indexed for MEDLINE]Related articlesFree article

Membrane phosphoinositides control insulin secretion through their effects on ATP-sensitive K+ channel activity.

Lin CW, Yan F, Shimamura S, Barg S, Shyng SL.

Diabetes. 2005 Oct;54(10):2852-8.PMID: 16186385 [PubMed - indexed for MEDLINE]Related articlesFree article