PubMed

CCL4 protects from type 1 diabetes by altering islet beta-cell-targeted inflammatory responses.

Meagher C, Arreaza G, Peters A, Strathdee CA, Gilbert PA, Mi QS, Santamaria P, Dekaban GA, Delovitch TL.

Diabetes. 2007 Mar;56(3):809-17.PMID: 17327452 [PubMed - indexed for MEDLINE]Related articlesFree article

Differential expression of CC chemokines and the CCR5 receptor in the pancreas is associated with progression to type I diabetes.

Cameron MJ, Arreaza GA, Grattan M, Meagher C, Sharif S, Burdick MD, Strieter RM, Cook DN, Delovitch TL.

J Immunol. 2000 Jul 15;165(2):1102-10.PMID: 10878389 [PubMed - indexed for MEDLINE]Related articlesFree article

Pancreatic IL-4 expression results in islet-reactive Th2 cells that inhibit diabetogenic lymphocytes in the nonobese diabetic mouse.

Gallichan WS, Balasa B, Davies JD, Sarvetnick N.

J Immunol. 1999 Aug 1;163(3):1696-703.PMID: 10415077 [PubMed - indexed for MEDLINE]Related articlesFree article

IL-4 prevents insulitis and insulin-dependent diabetes mellitus in nonobese diabetic mice by potentiation of regulatory T helper-2 cell function.

Cameron MJ, Arreaza GA, Zucker P, Chensue SW, Strieter RM, Chakrabarti S, Delovitch TL.

J Immunol. 1997 Nov 15;159(10):4686-92.PMID: 9366391 [PubMed - indexed for MEDLINE]Related articles

Protection against autoimmune diabetes with oral insulin is associated with the presence of IL-4 type 2 T-cells in the pancreas and pancreatic lymph nodes.

Ploix C, Bergerot I, Fabien N, Perche S, Moulin V, Thivolet C.

Diabetes. 1998 Jan;47(1):39-44.PMID: 9421372 [PubMed - indexed for MEDLINE]Related articles

A Reg family protein is overexpressed in islets from a patient with new-onset type 1 diabetes and acts as T-cell autoantigen in NOD mice.

Gurr W, Yavari R, Wen L, Shaw M, Mora C, Christa L, Sherwin RS.

Diabetes. 2002 Feb;51(2):339-46.PMID: 11812740 [PubMed - indexed for MEDLINE]Related articlesFree article

Suppressor of cytokine signaling-1 overexpression protects pancreatic beta cells from CD8+ T cell-mediated autoimmune destruction.

Chong MM, Chen Y, Darwiche R, Dudek NL, Irawaty W, Santamaria P, Allison J, Kay TW, Thomas HE.

J Immunol. 2004 May 1;172(9):5714-21.PMID: 15100317 [PubMed - indexed for MEDLINE]Related articlesFree article

Insulin-like growth factor (IGF)-I/IGF-binding protein-3 complex: therapeutic efficacy and mechanism of protection against type 1 diabetes.

Chen W, Salojin KV, Mi QS, Grattan M, Meagher TC, Zucker P, Delovitch TL.

Endocrinology. 2004 Feb;145(2):627-38. Epub 2003 Nov 14.PMID: 14617576 [PubMed - indexed for MEDLINE]Related articlesFree article

Interleukin-4 but not interleukin-10 protects against spontaneous and recurrent type 1 diabetes by activated CD1d-restricted invariant natural killer T-cells.

Mi QS, Ly D, Zucker P, McGarry M, Delovitch TL.

Diabetes. 2004 May;53(5):1303-10.PMID: 15111500 [PubMed - indexed for MEDLINE]Related articlesFree article

Transgenic expression of single-chain anti-CTLA-4 Fv on beta cells protects nonobese diabetic mice from autoimmune diabetes.

Shieh SJ, Chou FC, Yu PN, Lin WC, Chang DM, Roffler SR, Sytwu HK.

J Immunol. 2009 Aug 15;183(4):2277-85. Epub 2009 Jul 27.PMID: 19635924 [PubMed - indexed for MEDLINE]Related articles

Anti-CD43 monoclonal antibody L11 blocks migration of T cells to inflamed pancreatic islets and prevents development of diabetes in nonobese diabetic mice.

Johnson GG, Mikulowska A, Butcher EC, McEvoy LM, Michie SA.

J Immunol. 1999 Nov 15;163(10):5678-85.PMID: 10553098 [PubMed - indexed for MEDLINE]Related articlesFree article

Suppression of autoimmune diabetes by soluble galectin-1.

Perone MJ, Bertera S, Shufesky WJ, Divito SJ, Montecalvo A, Mathers AR, Larregina AT, Pang M, Seth N, Wucherpfennig KW, Trucco M, Baum LG, Morelli AE.

J Immunol. 2009 Mar 1;182(5):2641-53.PMID: 19234158 [PubMed - indexed for MEDLINE]Related articles

Cytokine- and costimulation-mediated therapy of IDDM.

Cameron MJ, Arreaza GA, Delovitch TL.

Crit Rev Immunol. 1997;17(5-6):537-44. Review.PMID: 9419441 [PubMed - indexed for MEDLINE]Related articles

The activity of immunoregulatory T cells mediating active tolerance is potentiated in nonobese diabetic mice by an IL-4-based retroviral gene therapy.

Yamamoto AM, Chernajovsky Y, Lepault F, Podhajcer O, Feldmann M, Bach JF, Chatenoud L.

J Immunol. 2001 Apr 15;166(8):4973-80.PMID: 11290776 [PubMed - indexed for MEDLINE]Related articlesFree article

Cyclin-dependent kinase 4 hyperactivity promotes autoreactivity in the immune system but protects pancreatic cell mass from autoimmune destruction in the nonobese diabetic mouse model.

Marzo N, Ortega S, Stratmann T, García A, Ríos M, Giménez A, Gomis R, Mora C.

J Immunol. 2008 Jan 15;180(2):1189-98.PMID: 18178859 [PubMed - indexed for MEDLINE]Related articlesFree article

Lentivirus-mediated transduction of islet grafts with interleukin 4 results in sustained gene expression and protection from insulitis.

Gallichan WS, Kafri T, Krahl T, Verma IM, Sarvetnick N.

Hum Gene Ther. 1998 Dec 10;9(18):2717-26.PMID: 9874270 [PubMed - indexed for MEDLINE]Related articles

Induction of robust diabetes resistance and prevention of recurrent type 1 diabetes following islet transplantation by gene therapy.

Tian C, Ansari MJ, Paez-Cortez J, Bagley J, Godwin J, Donnarumma M, Sayegh MH, Iacomini J.

J Immunol. 2007 Nov 15;179(10):6762-9.PMID: 17982066 [PubMed - indexed for MEDLINE]Related articlesFree article

Essential role for signal transducer and activator of transcription-1 in pancreatic beta-cell death and autoimmune type 1 diabetes of nonobese diabetic mice.

Kim S, Kim HS, Chung KW, Oh SH, Yun JW, Im SH, Lee MK, Kim KW, Lee MS.

Diabetes. 2007 Oct;56(10):2561-8. Epub 2007 Jul 9.PMID: 17620422 [PubMed - indexed for MEDLINE]Related articlesFree article

Marginal-zone B-cells of nonobese diabetic mice expand with diabetes onset, invade the pancreatic lymph nodes, and present autoantigen to diabetogenic T-cells.

Mariño E, Batten M, Groom J, Walters S, Liuwantara D, Mackay F, Grey ST.

Diabetes. 2008 Feb;57(2):395-404. Epub 2007 Nov 19.PMID: 18025414 [PubMed - indexed for MEDLINE]Related articlesFree article

Biolistic-mediated interleukin 4 gene transfer prevents the onset of type 1 diabetes.

Cameron MJ, Strathdee CA, Holmes KD, Arreaza GA, Dekaban GA, Delovitch TL.

Hum Gene Ther. 2000 Aug 10;11(12):1647-56.PMID: 10954899 [PubMed - indexed for MEDLINE]Related articles