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    Results: 1 to 20 of 156

    1.

    Family history of diabetes links impaired substrate switching and reduced mitochondrial content in skeletal muscle.

    Ukropcova B, Sereda O, de Jonge L, Bogacka I, Nguyen T, Xie H, Bray GA, Smith SR.

    Diabetes. 2007 Mar;56(3):720-7.PMID: 17327442 [PubMed - indexed for MEDLINE]Related articlesFree article

    2.

    Type 2 diabetes mellitus and skeletal muscle metabolic function.

    Phielix E, Mensink M.

    Physiol Behav. 2008 May 23;94(2):252-8. Epub 2008 Jan 31. Review.PMID: 18342897 [PubMed - indexed for MEDLINE]Related articles

    3.

    Metabolic flexibility in the development of insulin resistance and type 2 diabetes: effects of lifestyle.

    Corpeleijn E, Saris WH, Blaak EE.

    Obes Rev. 2009 Mar;10(2):178-93. Epub 2009 Jan 15. Review.PMID: 19207879 [PubMed - indexed for MEDLINE]Related articles

    4.

    High-fat diet, muscular lipotoxicity and insulin resistance.

    Schrauwen P.

    Proc Nutr Soc. 2007 Feb;66(1):33-41.PMID: 17343770 [PubMed - indexed for MEDLINE]Related articles

    5.

    A high-fat diet coordinately downregulates genes required for mitochondrial oxidative phosphorylation in skeletal muscle.

    Sparks LM, Xie H, Koza RA, Mynatt R, Hulver MW, Bray GA, Smith SR.

    Diabetes. 2005 Jul;54(7):1926-33.PMID: 15983191 [PubMed - indexed for MEDLINE]Related articlesFree article

    6.

    Decreased insulin-stimulated ATP synthesis and phosphate transport in muscle of insulin-resistant offspring of type 2 diabetic parents.

    Petersen KF, Dufour S, Shulman GI.

    PLoS Med. 2005 Sep;2(9):e233. Epub 2005 Aug 16.PMID: 16089501 [PubMed - indexed for MEDLINE]Related articlesFree article

    7.

    Impaired fat oxidation after a single high-fat meal in insulin-sensitive nondiabetic individuals with a family history of type 2 diabetes.

    Heilbronn LK, Gregersen S, Shirkhedkar D, Hu D, Campbell LV.

    Diabetes. 2007 Aug;56(8):2046-53. Epub 2007 Apr 24.PMID: 17456847 [PubMed - indexed for MEDLINE]Related articlesFree article

    8.

    Impaired mitochondrial substrate oxidation in muscle of insulin-resistant offspring of type 2 diabetic patients.

    Befroy DE, Petersen KF, Dufour S, Mason GF, de Graaf RA, Rothman DL, Shulman GI.

    Diabetes. 2007 May;56(5):1376-81. Epub 2007 Feb 7.PMID: 17287462 [PubMed - indexed for MEDLINE]Related articlesFree article

    9.

    Oxidative stress in skeletal muscle impairs mitochondrial respiration and limits exercise capacity in type 2 diabetic mice.

    Yokota T, Kinugawa S, Hirabayashi K, Matsushima S, Inoue N, Ohta Y, Hamaguchi S, Sobirin MA, Ono T, Suga T, Kuroda S, Tanaka S, Terasaki F, Okita K, Tsutsui H.

    Am J Physiol Heart Circ Physiol. 2009 Sep;297(3):H1069-77. Epub 2009 Jul 17.PMID: 19617406 [PubMed - indexed for MEDLINE]Related articles

    10.

    A discordance in rosiglitazone mediated insulin sensitization and skeletal muscle mitochondrial content/activity in Type 2 diabetes mellitus.

    Pagel-Langenickel I, Schwartz DR, Arena RA, Minerbi DC, Johnson DT, Waclawiw MA, Cannon RO 3rd, Balaban RS, Tripodi DJ, Sack MN.

    Am J Physiol Heart Circ Physiol. 2007 Nov;293(5):H2659-66. Epub 2007 Sep 21.PMID: 17890427 [PubMed - indexed for MEDLINE]Related articlesFree article

    11.

    Skeletal muscle mitochondrial functions, mitochondrial DNA copy numbers, and gene transcript profiles in type 2 diabetic and nondiabetic subjects at equal levels of low or high insulin and euglycemia.

    Asmann YW, Stump CS, Short KR, Coenen-Schimke JM, Guo Z, Bigelow ML, Nair KS.

    Diabetes. 2006 Dec;55(12):3309-19.PMID: 17130474 [PubMed - indexed for MEDLINE]Related articlesFree article

    12.

    Failure of fat cell proliferation, mitochondrial function and fat oxidation results in ectopic fat storage, insulin resistance and type II diabetes mellitus.

    Heilbronn L, Smith SR, Ravussin E.

    Int J Obes Relat Metab Disord. 2004 Dec;28 Suppl 4:S12-21. Review.PMID: 15592481 [PubMed - indexed for MEDLINE]Related articles

    13.

    Reduced mitochondrial density and increased IRS-1 serine phosphorylation in muscle of insulin-resistant offspring of type 2 diabetic parents.

    Morino K, Petersen KF, Dufour S, Befroy D, Frattini J, Shatzkes N, Neschen S, White MF, Bilz S, Sono S, Pypaert M, Shulman GI.

    J Clin Invest. 2005 Dec;115(12):3587-93. Epub 2005 Nov 10.PMID: 16284649 [PubMed - indexed for MEDLINE]Related articlesFree article

    14.

    Nicotinic acid-induced insulin resistance is related to increased circulating fatty acids and fat oxidation but not muscle lipid content.

    Poynten AM, Gan SK, Kriketos AD, O'Sullivan A, Kelly JJ, Ellis BA, Chisholm DJ, Campbell LV.

    Metabolism. 2003 Jun;52(6):699-704.PMID: 12800094 [PubMed - indexed for MEDLINE]Related articles

    15.

    High-fat diet impairs the effects of a single bout of endurance exercise on glucose transport and insulin sensitivity in rat skeletal muscle.

    Tanaka S, Hayashi T, Toyoda T, Hamada T, Shimizu Y, Hirata M, Ebihara K, Masuzaki H, Hosoda K, Fushiki T, Nakao K.

    Metabolism. 2007 Dec;56(12):1719-28.PMID: 17998027 [PubMed - indexed for MEDLINE]Related articles

    16.

    Dynamic changes in fat oxidation in human primary myocytes mirror metabolic characteristics of the donor.

    Ukropcova B, McNeil M, Sereda O, de Jonge L, Xie H, Bray GA, Smith SR.

    J Clin Invest. 2005 Jul;115(7):1934-41.PMID: 16007256 [PubMed - indexed for MEDLINE]Related articlesFree article

    17.

    Skeletal muscle "mitochondrial deficiency" does not mediate insulin resistance.

    Holloszy JO.

    Am J Clin Nutr. 2009 Jan;89(1):463S-6S. Epub 2008 Dec 3. Review.PMID: 19056574 [PubMed - indexed for MEDLINE]Related articles

    18.

    Metabolic flexibility and insulin resistance.

    Galgani JE, Moro C, Ravussin E.

    Am J Physiol Endocrinol Metab. 2008 Nov;295(5):E1009-17. Epub 2008 Sep 2. Review.PMID: 18765680 [PubMed - indexed for MEDLINE]Related articlesFree article

    19.

    Mitochondrial dysfunction results from oxidative stress in the skeletal muscle of diet-induced insulin-resistant mice.

    Bonnard C, Durand A, Peyrol S, Chanseaume E, Chauvin MA, Morio B, Vidal H, Rieusset J.

    J Clin Invest. 2008 Feb;118(2):789-800.PMID: 18188455 [PubMed - indexed for MEDLINE]Related articlesFree article

    20.

    Dissociation of obesity and insulin resistance in transgenic mice with skeletal muscle expression of uncoupling protein 1.

    Katterle Y, Keipert S, Hof J, Klaus S.

    Physiol Genomics. 2008 Feb 19;32(3):352-9. Epub 2007 Nov 27.PMID: 18042832 [PubMed - indexed for MEDLINE]Related articlesFree article

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