PubMed

CD8+ T-cell responses identify beta-cell autoimmunity in human type 1 diabetes.

Mallone R, Martinuzzi E, Blancou P, Novelli G, Afonso G, Dolz M, Bruno G, Chaillous L, Chatenoud L, Bach JM, van Endert P.

Diabetes. 2007 Mar;56(3):613-21.PMID: 17327428 [PubMed - indexed for MEDLINE]Related articlesFree article

The frequency and immunodominance of islet-specific CD8+ T-cell responses change after type 1 diabetes diagnosis and treatment.

Martinuzzi E, Novelli G, Scotto M, Blancou P, Bach JM, Chaillous L, Bruno G, Chatenoud L, van Endert P, Mallone R.

Diabetes. 2008 May;57(5):1312-20. Epub 2008 Feb 27.PMID: 18305140 [PubMed - indexed for MEDLINE]Related articlesFree article

Equivalent specificity of peripheral blood and islet-infiltrating CD8+ T lymphocytes in spontaneously diabetic HLA-A2 transgenic NOD mice.

Enée E, Martinuzzi E, Blancou P, Bach JM, Mallone R, van Endert P.

J Immunol. 2008 Apr 15;180(8):5430-8.PMID: 18390725 [PubMed - indexed for MEDLINE]Related articlesFree article

Recognition of HLA class I-restricted beta-cell epitopes in type 1 diabetes.

Ouyang Q, Standifer NE, Qin H, Gottlieb P, Verchere CB, Nepom GT, Tan R, Panagiotopoulos C.

Diabetes. 2006 Nov;55(11):3068-74.PMID: 17065344 [PubMed - indexed for MEDLINE]Related articlesFree article

Early autoimmune destruction of islet grafts is associated with a restricted repertoire of IGRP-specific CD8+ T cells in diabetic nonobese diabetic mice.

Wong CP, Li L, Frelinger JA, Tisch R.

J Immunol. 2006 Feb 1;176(3):1637-44.PMID: 16424193 [PubMed - indexed for MEDLINE]Related articlesFree article

CD8 and cytotoxic T cells in type 1 diabetes.

Peakman M.

Novartis Found Symp. 2008;292:113-9; discussion 119-29, 202-3.PMID: 19203096 [PubMed - indexed for MEDLINE]Related articles

Identification of novel IGRP epitopes targeted in type 1 diabetes patients.

Jarchum I, Nichol L, Trucco M, Santamaria P, DiLorenzo TP.

Clin Immunol. 2008 Jun;127(3):359-65. Epub 2008 Mar 20.PMID: 18358785 [PubMed - indexed for MEDLINE]Related articlesFree article

Islet-specific glucose-6-phosphatase catalytic subunit-related protein-reactive CD4+ T cells in human subjects.

Yang J, Danke NA, Berger D, Reichstetter S, Reijonen H, Greenbaum C, Pihoker C, James EA, Kwok WW.

J Immunol. 2006 Mar 1;176(5):2781-9.PMID: 16493034 [PubMed - indexed for MEDLINE]Related articlesFree article

A new role for an old player: do B cells unleash the self-reactive CD8+ T cell storm necessary for the development of type 1 diabetes?

Mariño E, Grey ST.

J Autoimmun. 2008 Nov;31(3):301-5. Epub 2008 Sep 21. Review.PMID: 18809297 [PubMed - indexed for MEDLINE]Related articles

Serum-free culture medium and IL-7 costimulation increase the sensitivity of ELISpot detection.

Martinuzzi E, Scotto M, Enée E, Brezar V, Ribeil JA, van Endert P, Mallone R.

J Immunol Methods. 2008 Apr 20;333(1-2):61-70. Epub 2008 Jan 29.PMID: 18242633 [PubMed - indexed for MEDLINE]Related articles

"Humanized" HLA transgenic NOD mice to identify pancreatic beta cell autoantigens of potential clinical relevance to type 1 diabetes.

Serreze DV, Marron MP, Dilorenzo TP.

Ann N Y Acad Sci. 2007 Apr;1103:103-11. Epub 2007 Mar 21.PMID: 17376821 [PubMed - indexed for MEDLINE]Related articles

Immunization of HLA class I transgenic mice identifies autoantigenic epitopes eliciting dominant responses in type 1 diabetes patients.

Blancou P, Mallone R, Martinuzzi E, Sévère S, Pogu S, Novelli G, Bruno G, Charbonnel B, Dolz M, Chaillous L, van Endert P, Bach JM.

J Immunol. 2007 Jun 1;178(11):7458-66.PMID: 17513797 [PubMed - indexed for MEDLINE]Related articlesFree article

HLA-A*0201-restricted T cells from humanized NOD mice recognize autoantigens of potential clinical relevance to type 1 diabetes.

Takaki T, Marron MP, Mathews CE, Guttmann ST, Bottino R, Trucco M, DiLorenzo TP, Serreze DV.

J Immunol. 2006 Mar 1;176(5):3257-65.PMID: 16493087 [PubMed - indexed for MEDLINE]Related articlesFree article

HLA class I epitope discovery in type 1 diabetes.

van Endert P, Hassainya Y, Lindo V, Bach JM, Blancou P, Lemonnier F, Mallone R.

Ann N Y Acad Sci. 2006 Oct;1079:190-7.PMID: 17130554 [PubMed - indexed for MEDLINE]Related articles

In vivo cytotoxicity of insulin-specific CD8+ T-cells in HLA-A*0201 transgenic NOD mice.

Jarchum I, Baker JC, Yamada T, Takaki T, Marron MP, Serreze DV, DiLorenzo TP.

Diabetes. 2007 Oct;56(10):2551-60. Epub 2007 Jul 9.PMID: 17620420 [PubMed - indexed for MEDLINE]Related articlesFree article

Autoreactive CD8 T cells associated with beta cell destruction in type 1 diabetes.

Pinkse GG, Tysma OH, Bergen CA, Kester MG, Ossendorp F, van Veelen PA, Keymeulen B, Pipeleers D, Drijfhout JW, Roep BO.

Proc Natl Acad Sci U S A. 2005 Dec 20;102(51):18425-30. Epub 2005 Dec 9.PMID: 16339897 [PubMed - indexed for MEDLINE]Related articlesFree article

CD8+ T lymphocytes specific for glutamic acid decarboxylase 90-98 epitope mediate diabetes in NOD SCID mouse.

Sévère S, Gauvrit A, Vu AT, Bach JM.

Mol Immunol. 2007 Apr;44(11):2950-60. Epub 2007 Mar 2.PMID: 17336387 [PubMed - indexed for MEDLINE]Related articles

CTLs are targeted to kill beta cells in patients with type 1 diabetes through recognition of a glucose-regulated preproinsulin epitope.

Skowera A, Ellis RJ, Varela-Calviño R, Arif S, Huang GC, Van-Krinks C, Zaremba A, Rackham C, Allen JS, Tree TI, Zhao M, Dayan CM, Sewell AK, Unger WW, Drijfhout JW, Ossendorp F, Roep BO, Peakman M.

J Clin Invest. 2008 Oct;118(10):3390-402. Erratum in: J Clin Invest. 2009 Sep;119(9):2844. Unger, Wendy [corrected to Unger, Wendy W]. PMID: 18802479 [PubMed - indexed for MEDLINE]Related articlesFree article

Human CD8 responses to a complete epitope set from preproinsulin: implications for approaches to epitope discovery.

Baker C, Petrich de Marquesini LG, Bishop AJ, Hedges AJ, Dayan CM, Wong FS.

J Clin Immunol. 2008 Jul;28(4):350-60. Epub 2008 Feb 29.PMID: 18311511 [PubMed - indexed for MEDLINE]Related articles

Cytochrome P450IID6-specific CD8 T cell immune responses mirror disease activity in autoimmune hepatitis type 2.

Longhi MS, Hussain MJ, Bogdanos DP, Quaglia A, Mieli-Vergani G, Ma Y, Vergani D.

Hepatology. 2007 Aug;46(2):472-84.PMID: 17559153 [PubMed - indexed for MEDLINE]Related articles