PubMed

Association studies of BMI and type 2 diabetes in the neuropeptide Y pathway: a possible role for NPY2R as a candidate gene for type 2 diabetes in men.

Campbell CD, Lyon HN, Nemesh J, Drake JA, Tuomi T, Gaudet D, Zhu X, Cooper RS, Ardlie KG, Groop LC, Hirschhorn JN.

Diabetes. 2007 May;56(5):1460-7. Epub 2007 Feb 26.PMID: 17325259 [PubMed - indexed for MEDLINE]Related articlesFree article

Single nucleotide polymorphisms in the neuropeptide Y2 receptor (NPY2R) gene and association with severe obesity in French white subjects.

Siddiq A, Gueorguiev M, Samson C, Hercberg S, Heude B, Levy-Marchal C, Jouret B, Weill J, Meyre D, Walley A, Froguel P.

Diabetologia. 2007 Mar;50(3):574-84. Epub 2007 Jan 18.PMID: 17235527 [PubMed - indexed for MEDLINE]Related articles

Variants in the 5' region of the neuropeptide Y receptor Y2 gene (NPY2R) are associated with obesity in 5,971 white subjects.

Torekov SS, Larsen LH, Andersen G, Albrechtsen A, Glümer C, Borch-Johnsen K, Jørgensen T, Hansen T, Pedersen O.

Diabetologia. 2006 Nov;49(11):2653-8. Epub 2006 Sep 22.PMID: 17019604 [PubMed - indexed for MEDLINE]Related articles

Novel genetic variants contributing to left ventricular hypertrophy: the HyperGEN study.

Arnett DK, Devereux RB, Rao DC, Li N, Tang W, Kraemer R, Claas SA, Leon JM, Broeckel U.

J Hypertens. 2009 Aug;27(8):1585-93.PMID: 19593212 [PubMed - indexed for MEDLINE]Related articles

Variations in peptide YY and Y2 receptor genes are associated with severe obesity in Pima Indian men.

Ma L, Tataranni PA, Hanson RL, Infante AM, Kobes S, Bogardus C, Baier LJ.

Diabetes. 2005 May;54(5):1598-602.PMID: 15855352 [PubMed - indexed for MEDLINE]Related articlesFree article

Variations in the HHEX gene are associated with increased risk of type 2 diabetes in the Japanese population.

Horikoshi M, Hara K, Ito C, Shojima N, Nagai R, Ueki K, Froguel P, Kadowaki T.

Diabetologia. 2007 Dec;50(12):2461-6. Epub 2007 Oct 10.PMID: 17928989 [PubMed - indexed for MEDLINE]Related articles

Identification of novel candidate genes for type 2 diabetes from a genome-wide association scan in the Old Order Amish: evidence for replication from diabetes-related quantitative traits and from independent populations.

Rampersaud E, Damcott CM, Fu M, Shen H, McArdle P, Shi X, Shelton J, Yin J, Chang YP, Ott SH, Zhang L, Zhao Y, Mitchell BD, O'Connell J, Shuldiner AR.

Diabetes. 2007 Dec;56(12):3053-62. Epub 2007 Sep 10.PMID: 17846126 [PubMed - indexed for MEDLINE]Related articlesFree article

Study of association between common variation in the insulin-like growth factor 2 gene and indices of obesity and body size in middle-aged men and women.

Heude B, Ong KK, Luben R, Wareham NJ, Sandhu MS.

J Clin Endocrinol Metab. 2007 Jul;92(7):2734-8. Epub 2007 May 8.PMID: 17488802 [PubMed - indexed for MEDLINE]Related articlesFree article

Polymorphisms of the low-density lipoprotein receptor-related protein 5 (LRP5) gene are associated with obesity phenotypes in a large family-based association study.

Guo YF, Xiong DH, Shen H, Zhao LJ, Xiao P, Guo Y, Wang W, Yang TL, Recker RR, Deng HW.

J Med Genet. 2006 Oct;43(10):798-803. Epub 2006 May 24.PMID: 16723389 [PubMed - indexed for MEDLINE]Related articlesFree article

Novel polymorphisms in the neuropeptide-Y Y5 receptor associated with obesity in Pima Indians.

Jenkinson CP, Cray K, Walder K, Herzog H, Hanson, Ravussin E.

Int J Obes Relat Metab Disord. 2000 May;24(5):580-4.PMID: 10849579 [PubMed - indexed for MEDLINE]Related articles

No association of sequence variants in the neuropeptide Y2 receptor (NPY2R) gene with early onset obesity in Germans.

Wang HJ, Wermter AK, Nguyen TT, Scherag A, Reichwald K, Waldenmaier B, Lichtner P, Bettecken T, Hebebrand J, Hinney A.

Horm Metab Res. 2007 Nov;39(11):840-4.PMID: 17992642 [PubMed - indexed for MEDLINE]Related articles

Genome-wide association scan shows genetic variants in the FTO gene are associated with obesity-related traits.

Scuteri A, Sanna S, Chen WM, Uda M, Albai G, Strait J, Najjar S, Nagaraja R, Orrú M, Usala G, Dei M, Lai S, Maschio A, Busonero F, Mulas A, Ehret GB, Fink AA, Weder AB, Cooper RS, Galan P, Chakravarti A, Schlessinger D, Cao A, Lakatta E, Abecasis GR.

PLoS Genet. 2007 Jul;3(7):e115.PMID: 17658951 [PubMed - indexed for MEDLINE]Related articlesFree article

Neuropeptide Y receptor genes are associated with alcohol dependence, alcohol withdrawal phenotypes, and cocaine dependence.

Wetherill L, Schuckit MA, Hesselbrock V, Xuei X, Liang T, Dick DM, Kramer J, Nurnberger JI Jr, Tischfield JA, Porjesz B, Edenberg HJ, Foroud T.

Alcohol Clin Exp Res. 2008 Dec;32(12):2031-40. Epub 2008 Sep 25.PMID: 18828811 [PubMed - indexed for MEDLINE]Related articlesFree article

Common neuropeptide Y2 receptor gene variant is protective against obesity among Swedish men.

Lavebratt C, Alpman A, Persson B, Arner P, Hoffstedt J.

Int J Obes (Lond). 2006 Mar;30(3):453-9.PMID: 16331299 [PubMed - indexed for MEDLINE]Related articles

Evaluation of common variants in the six known maturity-onset diabetes of the young (MODY) genes for association with type 2 diabetes.

Winckler W, Weedon MN, Graham RR, McCarroll SA, Purcell S, Almgren P, Tuomi T, Gaudet D, Boström KB, Walker M, Hitman G, Hattersley AT, McCarthy MI, Ardlie KG, Hirschhorn JN, Daly MJ, Frayling TM, Groop L, Altshuler D.

Diabetes. 2007 Mar;56(3):685-93.PMID: 17327436 [PubMed - indexed for MEDLINE]Related articlesFree article

Association of neuropeptide Y receptor Y5 polymorphisms with dyslipidemia in Mexican Americans.

Coletta DK, Schneider J, Stern MP, Blangero J, DeFronzo RA, Duggirala R, Jenkinson CP.

Obesity (Silver Spring). 2007 Apr;15(4):809-15.PMID: 17426313 [PubMed - indexed for MEDLINE]Related articles

Effects of genetic variation in the human retinol binding protein-4 gene (RBP4) on insulin resistance and fat depot-specific mRNA expression.

Kovacs P, Geyer M, Berndt J, Klöting N, Graham TE, Böttcher Y, Enigk B, Tönjes A, Schleinitz D, Schön MR, Kahn BB, Blüher M, Stumvoll M.

Diabetes. 2007 Dec;56(12):3095-100. Epub 2007 Aug 29.PMID: 17728376 [PubMed - indexed for MEDLINE]Related articlesFree article

LPIN2 is associated with type 2 diabetes, glucose metabolism, and body composition.

Aulchenko YS, Pullen J, Kloosterman WP, Yazdanpanah M, Hofman A, Vaessen N, Snijders PJ, Zubakov D, Mackay I, Olavesen M, Sidhu B, Smith VE, Carey A, Berezikov E, Uitterlinden AG, Plasterk RH, Oostra BA, van Duijn CM.

Diabetes. 2007 Dec;56(12):3020-6. Epub 2007 Sep 5.PMID: 17804763 [PubMed - indexed for MEDLINE]Related articlesFree article

Variation within the gene encoding the upstream stimulatory factor 1 does not influence susceptibility to type 2 diabetes in samples from populations with replicated evidence of linkage to chromosome 1q.

Zeggini E, Damcott CM, Hanson RL, Karim MA, Rayner NW, Groves CJ, Baier LJ, Hale TC, Hattersley AT, Hitman GA, Hunt SE, Knowler WC, Mitchell BD, Ng MC, O'Connell JR, Pollin TI, Vaxillaire M, Walker M, Wang X, Whittaker P, Xiang K, Jia W, Chan JC, Froguel P, Deloukas P, Shuldiner AR, Elbein SC, McCarthy MI; International Type 2 Diabetes 1q Consortium.

Diabetes. 2006 Sep;55(9):2541-8. Erratum in: Diabetes. 2006 Nov;55(11):3197. Kunsun, Xiang [corrected to Xiang, Kunsan]. PMID: 16936202 [PubMed - indexed for MEDLINE]Related articlesFree article

Common variants in the ENPP1 gene are not reproducibly associated with diabetes or obesity.

Lyon HN, Florez JC, Bersaglieri T, Saxena R, Winckler W, Almgren P, Lindblad U, Tuomi T, Gaudet D, Zhu X, Cooper R, Ardlie KG, Daly MJ, Altshuler D, Groop L, Hirschhorn JN.

Diabetes. 2006 Nov;55(11):3180-4.PMID: 17065359 [PubMed - indexed for MEDLINE]Related articlesFree article