PubMed

TGF-beta dependent regulation of oxygen radicals during transdifferentiation of activated hepatic stellate cells to myofibroblastoid cells.

Proell V, Carmona-Cuenca I, Murillo MM, Huber H, Fabregat I, Mikulits W.

Comp Hepatol. 2007 Feb 20;6:1.PMID: 17311678 [PubMed]Related articlesFree article

Opposing effects of oestradiol and progesterone on intracellular pathways and activation processes in the oxidative stress induced activation of cultured rat hepatic stellate cells.

Itagaki T, Shimizu I, Cheng X, Yuan Y, Oshio A, Tamaki K, Fukuno H, Honda H, Okamura Y, Ito S.

Gut. 2005 Dec;54(12):1782-9. Erratum in: Gut. 2008 Nov;57(11):1634. PMID: 16284289 [PubMed - indexed for MEDLINE]Related articlesFree article

Phagocytosis of apoptotic bodies by hepatic stellate cells induces NADPH oxidase and is associated with liver fibrosis in vivo.

Zhan SS, Jiang JX, Wu J, Halsted C, Friedman SL, Zern MA, Torok NJ.

Hepatology. 2006 Mar;43(3):435-43.PMID: 16496318 [PubMed - indexed for MEDLINE]Related articles

Activated hepatic stellate cells induce tumor progression of neoplastic hepatocytes in a TGF-beta dependent fashion.

Mikula M, Proell V, Fischer AN, Mikulits W.

J Cell Physiol. 2006 Nov;209(2):560-7.PMID: 16883581 [PubMed - indexed for MEDLINE]Related articles

Reduced nicotinamide adenine dinucleotide phosphate oxidase mediates fibrotic and inflammatory effects of leptin on hepatic stellate cells.

De Minicis S, Seki E, Oesterreicher C, Schnabl B, Schwabe RF, Brenner DA.

Hepatology. 2008 Dec;48(6):2016-26.PMID: 19025999 [PubMed - indexed for MEDLINE]Related articles

Modulation of intracellular reactive oxygen species level in chondrocytes by IGF-1, FGF, and TGF-beta1.

Jallali N, Ridha H, Thrasivoulou C, Butler P, Cowen T.

Connect Tissue Res. 2007;48(3):149-58.PMID: 17522998 [PubMed - indexed for MEDLINE]Related articles

The inhibition of the epidermal growth factor (EGF) pathway enhances TGF-beta-induced apoptosis in rat hepatoma cells through inducing oxidative stress coincident with a change in the expression pattern of the NADPH oxidases (NOX) isoforms.

Sancho P, Bertran E, Caja L, Carmona-Cuenca I, Murillo MM, Fabregat I.

Biochim Biophys Acta. 2009 Feb;1793(2):253-63. Epub 2008 Sep 24.PMID: 18848961 [PubMed - indexed for MEDLINE]Related articles

Overactivation of the MEK/ERK pathway in liver tumor cells confers resistance to TGF-{beta}-induced cell death through impairing up-regulation of the NADPH oxidase NOX4.

Caja L, Sancho P, Bertran E, Iglesias-Serret D, Gil J, Fabregat I.

Cancer Res. 2009 Oct 1;69(19):7595-602. Epub 2009 Sep 22.PMID: 19773433 [PubMed - indexed for MEDLINE]Related articles

Hepatitis C virus (HCV) proteins induce NADPH oxidase 4 expression in a transforming growth factor beta-dependent manner: a new contributor to HCV-induced oxidative stress.

Boudreau HE, Emerson SU, Korzeniowska A, Jendrysik MA, Leto TL.

J Virol. 2009 Dec;83(24):12934-46. Epub 2009 Oct 7.PMID: 19812163 [PubMed - indexed for MEDLINE]Related articles

Activation of NADPH oxidase by transforming growth factor-beta in hepatocytes mediates up-regulation of epidermal growth factor receptor ligands through a nuclear factor-kappaB-dependent mechanism.

Murillo MM, Carmona-Cuenca I, Del Castillo G, Ortiz C, Roncero C, Sánchez A, Fernández M, Fabregat I.

Biochem J. 2007 Jul 15;405(2):251-9.PMID: 17407446 [PubMed - indexed for MEDLINE]Related articlesFree article

Superoxide anions and hydrogen peroxide inhibit proliferation of activated rat stellate cells and induce different modes of cell death.

Dunning S, Hannivoort RA, de Boer JF, Buist-Homan M, Faber KN, Moshage H.

Liver Int. 2009 Jul;29(6):922-32. Epub 2009 Apr 6.PMID: 19386027 [PubMed - indexed for MEDLINE]Related articles

Profibrogenic transforming growth factor-beta/activin receptor-like kinase 5 signaling via connective tissue growth factor expression in hepatocytes.

Weng HL, Ciuclan L, Liu Y, Hamzavi J, Godoy P, Gaitantzi H, Kanzler S, Heuchel R, Ueberham U, Gebhardt R, Breitkopf K, Dooley S.

Hepatology. 2007 Oct;46(4):1257-70.PMID: 17657819 [PubMed - indexed for MEDLINE]Related articles

High glucose activates PKC-zeta and NADPH oxidase through autocrine TGF-beta1 signaling in mesangial cells.

Xia L, Wang H, Munk S, Kwan J, Goldberg HJ, Fantus IG, Whiteside CI.

Am J Physiol Renal Physiol. 2008 Dec;295(6):F1705-14. Epub 2008 Sep 24.PMID: 18815221 [PubMed - indexed for MEDLINE]Related articlesFree article

Upregulation of the NADPH oxidase NOX4 by TGF-beta in hepatocytes is required for its pro-apoptotic activity.

Carmona-Cuenca I, Roncero C, Sancho P, Caja L, Fausto N, Fernández M, Fabregat I.

J Hepatol. 2008 Dec;49(6):965-76. Epub 2008 Sep 19.PMID: 18845355 [PubMed - indexed for MEDLINE]Related articles

Loss of TGF-beta dependent growth control during HSC transdifferentiation.

Purps O, Lahme B, Gressner AM, Meindl-Beinker NM, Dooley S.

Biochem Biophys Res Commun. 2007 Feb 16;353(3):841-7. Epub 2006 Dec 26.PMID: 17204247 [PubMed - indexed for MEDLINE]Related articles

Kupffer cells mediate leptin-induced liver fibrosis.

Wang J, Leclercq I, Brymora JM, Xu N, Ramezani-Moghadam M, London RM, Brigstock D, George J.

Gastroenterology. 2009 Aug;137(2):713-23. Epub 2009 Apr 16.PMID: 19375424 [PubMed - indexed for MEDLINE]Related articles

Extracts of Lindera obtusiloba induce antifibrotic effects in hepatic stellate cells via suppression of a TGF-beta-mediated profibrotic gene expression pattern.

Ruehl M, Erben U, Kim K, Freise C, Dagdelen T, Eisele S, Trowitzsch-Kienast W, Zeitz M, Jia J, Stickel F, Somasundaram R.

J Nutr Biochem. 2009 Aug;20(8):597-606. Epub 2008 Sep 27.PMID: 18824344 [PubMed - indexed for MEDLINE]Related articles

Adenosine inhibits cytosolic calcium signals and chemotaxis in hepatic stellate cells.

Hashmi AZ, Hakim W, Kruglov EA, Watanabe A, Watkins W, Dranoff JA, Mehal WZ.

Am J Physiol Gastrointest Liver Physiol. 2007 Jan;292(1):G395-401. Epub 2006 Oct 19.PMID: 17053161 [PubMed - indexed for MEDLINE]Related articlesFree article

Zinc supplementation attenuates ethanol- and acetaldehyde-induced liver stellate cell activation by inhibiting reactive oxygen species (ROS) production and by influencing intracellular signaling.

Szuster-Ciesielska A, Plewka K, Daniluk J, Kandefer-Szerszeń M.

Biochem Pharmacol. 2009 Aug 1;78(3):301-14. Epub 2009 Apr 17.PMID: 19376089 [PubMed - indexed for MEDLINE]Related articles

Adenoviral delivery of dominant-negative transforming growth factor beta type II receptor up-regulates transcriptional repressor SKI-like oncogene, decreases matrix metalloproteinase 2 in hepatic stellate cell and prevents liver fibrosis in rats.

Marquez-Aguirre A, Sandoval-Rodriguez A, Gonzalez-Cuevas J, Bueno-Topete M, Navarro-Partida J, Arellano-Olivera I, Lucano-Landeros S, Armendariz-Borunda J.

J Gene Med. 2009 Mar;11(3):207-19.PMID: 19189315 [PubMed - indexed for MEDLINE]Related articles