PubMed

Caspase inhibitor therapy enhances marginal mass islet graft survival and preserves long-term function in islet transplantation.

Emamaullee JA, Stanton L, Schur C, Shapiro AM.

Diabetes. 2007 May;56(5):1289-98. Epub 2007 Feb 15.PMID: 17303806 [PubMed - indexed for MEDLINE]Related articlesFree article

The caspase selective inhibitor EP1013 augments human islet graft function and longevity in marginal mass islet transplantation in mice.

Emamaullee JA, Davis J, Pawlick R, Toso C, Merani S, Cai SX, Tseng B, Shapiro AM.

Diabetes. 2008 Jun;57(6):1556-66. Epub 2008 Mar 20.PMID: 18356409 [PubMed - indexed for MEDLINE]Related articlesFree article

Short-term culture with the caspase inhibitor z-VAD.fmk reduces beta cell apoptosis in transplanted islets and improves the metabolic outcome of the graft.

Montolio M, Téllez N, Biarnés M, Soler J, Montanya E.

Cell Transplant. 2005;14(1):59-65.PMID: 15789663 [PubMed - indexed for MEDLINE]Related articles

Porcine islet graft function is affected by pretreatment with a caspase-3 inhibitor.

Brandhorst D, Kumarasamy V, Maatoui A, Alt A, Bretzel RG, Brandhorst H.

Cell Transplant. 2006;15(4):311-7.PMID: 16898224 [PubMed - indexed for MEDLINE]Related articles

Caspase-3 inhibitor prevents apoptosis of human islets immediately after isolation and improves islet graft function.

Nakano M, Matsumoto I, Sawada T, Ansite J, Oberbroeckling J, Zhang HJ, Kirchhof N, Shearer J, Sutherland DE, Hering BJ.

Pancreas. 2004 Aug;29(2):104-9.PMID: 15257101 [PubMed - indexed for MEDLINE]Related articles

Exendin-4 does not promote Beta-cell proliferation or survival during the early post-islet transplant period in mice.

Crutchlow MF, Yu M, Bae YS, Deng S, Stoffers DA.

Transplant Proc. 2008 Jun;40(5):1650-7. Erratum in: Transplant Proc. 2009 Jan-Feb;41(1):450. PMID: 18589167 [PubMed - indexed for MEDLINE]Related articlesFree article

Cell-permeable pentapeptide V5 inhibits apoptosis and enhances insulin secretion, allowing experimental single-donor islet transplantation in mice.

Rivas-Carrillo JD, Soto-Gutierrez A, Navarro-Alvarez N, Noguchi H, Okitsu T, Chen Y, Yuasa T, Tanaka K, Narushima M, Miki A, Misawa H, Tabata Y, Jun HS, Matsumoto S, Fox IJ, Tanaka N, Kobayashi N.

Diabetes. 2007 May;56(5):1259-67. Epub 2007 Feb 7.PMID: 17287463 [PubMed - indexed for MEDLINE]Related articlesFree article

Activation of c-Jun NH2-terminal kinase (JNK) pathway during islet transplantation and prevention of islet graft loss by intraportal injection of JNK inhibitor.

Noguchi H, Nakai Y, Ueda M, Masui Y, Futaki S, Kobayashi N, Hayashi S, Matsumoto S.

Diabetologia. 2007 Mar;50(3):612-9. Epub 2007 Jan 16.PMID: 17225125 [PubMed - indexed for MEDLINE]Related articles

Porcine marginal mass islet autografts resist metabolic failure over time and are enhanced by early treatment with liraglutide.

Emamaullee JA, Merani S, Toso C, Kin T, Al-Saif F, Truong W, Pawlick R, Davis J, Edgar R, Lock J, Bonner-Weir S, Knudsen LB, Shapiro AM.

Endocrinology. 2009 May;150(5):2145-52. Epub 2009 Jan 8.PMID: 19131571 [PubMed - indexed for MEDLINE]Related articles

Effect of 15-deoxyspergualin on immediate function and long-term survival of transplanted islets in murine recipients of a marginal islet mass.

Kaufman DB, Gores PF, Field MJ, Farney AC, Gruber SA, Stephanian E, Sutherland DE.

Diabetes. 1994 Jun;43(6):778-83.PMID: 8194663 [PubMed - indexed for MEDLINE]Related articles

The effect of transplantation site and islet mass on long-term survival and metabolic and hormonal function of canine purified islet autografts.

Scharp DW, Marchetti P, Swanson C, Newton M, McCullough CS, Olack B.

Cell Transplant. 1992;1(2-3):245-54.PMID: 1344296 [PubMed - indexed for MEDLINE]Related articles

New mouse model to study islet transplantation in insulin-dependent diabetes mellitus.

Mathews CE, Langley SH, Leiter EH.

Transplantation. 2002 Apr 27;73(8):1333-6.PMID: 11981430 [PubMed - indexed for MEDLINE]Related articles

Improvement of the survival rate after rat massive hepatectomy due to the reduction of apoptosis by caspase inhibitor.

Yoshida N, Iwata H, Yamada T, Sekino T, Matsuo H, Shirahashi K, Miyahara T, Kiyama S, Takemura H.

J Gastroenterol Hepatol. 2007 Nov;22(11):2015-21. Epub 2007 Jun 7.PMID: 17559362 [PubMed - indexed for MEDLINE]Related articles

Intrathymic islet transplantation in the canine: I. Histological and functional evidence of autologous intrathymic islet engraftment and survival in pancreatectomized recipients.

Levy MM, Ketchum RJ, Tomaszewski JE, Naji A, Barker CF, Brayman KL.

Transplantation. 2002 Mar 27;73(6):842-52.PMID: 11923682 [PubMed - indexed for MEDLINE]Related articles

Local expression of B7-H4 by recombinant adenovirus transduction in mouse islets prolongs allograft survival.

Wang X, Hao J, Metzger DL, Mui A, Ao Z, Verchere CB, Chen L, Ou D, Warnock GL.

Transplantation. 2009 Feb 27;87(4):482-90.PMID: 19307783 [PubMed - indexed for MEDLINE]Related articles

Successful islet transplantation: continued insulin reserve provides long-term glycemic control.

Ryan EA, Lakey JR, Paty BW, Imes S, Korbutt GS, Kneteman NM, Bigam D, Rajotte RV, Shapiro AM.

Diabetes. 2002 Jul;51(7):2148-57.PMID: 12086945 [PubMed - indexed for MEDLINE]Related articlesFree article

Cytoprotection of pancreatic islets before and soon after transplantation by gene transfer of the anti-apoptotic Bcl-2 gene.

Contreras JL, Bilbao G, Smyth CA, Jiang XL, Eckhoff DE, Jenkins SM, Thomas FT, Curiel DT, Thomas JM.

Transplantation. 2001 Apr 27;71(8):1015-23.PMID: 11374395 [PubMed - indexed for MEDLINE]Related articles

Long-term survival and function of intrahepatic islet allografts in baboons treated with humanized anti-CD154.

Kenyon NS, Fernandez LA, Lehmann R, Masetti M, Ranuncoli A, Chatzipetrou M, Iaria G, Han D, Wagner JL, Ruiz P, Berho M, Inverardi L, Alejandro R, Mintz DH, Kirk AD, Harlan DM, Burkly LC, Ricordi C.

Diabetes. 1999 Jul;48(7):1473-81.PMID: 10389857 [PubMed - indexed for MEDLINE]Related articlesFree article

Exendin-4 treatment improves metabolic control after rat islet transplantation to athymic mice with streptozotocin-induced diabetes.

Sharma A, Sörenby A, Wernerson A, Efendic S, Kumagai-Braesch M, Tibell A.

Diabetologia. 2006 Jun;49(6):1247-53. Epub 2006 Apr 12.PMID: 16609877 [PubMed - indexed for MEDLINE]Related articles

BCG immunotherapy prevents recurrence of diabetes in islet grafts transplanted into spontaneously diabetic NOD mice.

Lakey JR, Singh B, Warnock GL, Rajotte RV.

Transplantation. 1994 Apr 27;57(8):1213-7.PMID: 8178349 [PubMed - indexed for MEDLINE]Related articles