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    Results: 1 to 20 of 182

    1.

    Genetic deletion of Trb3, the mammalian Drosophila tribbles homolog, displays normal hepatic insulin signaling and glucose homeostasis.

    Okamoto H, Latres E, Liu R, Thabet K, Murphy A, Valenzeula D, Yancopoulos GD, Stitt TN, Glass DJ, Sleeman MW.

    Diabetes. 2007 May;56(5):1350-6. Epub 2007 Feb 15.PMID: 17303803 [PubMed - indexed for MEDLINE]Related articlesFree article

    2.

    TRB3: a tribbles homolog that inhibits Akt/PKB activation by insulin in liver.

    Du K, Herzig S, Kulkarni RN, Montminy M.

    Science. 2003 Jun 6;300(5625):1574-7.PMID: 12791994 [PubMed - indexed for MEDLINE]Related articlesFree article

    3.

    Acute exercise reduces insulin resistance-induced TRB3 expression and amelioration of the hepatic production of glucose in the liver of diabetic mice.

    Lima AF, Ropelle ER, Pauli JR, Cintra DE, Frederico MJ, Pinho RA, Velloso LA, De Souza CT.

    J Cell Physiol. 2009 Oct;221(1):92-7.PMID: 19492410 [PubMed - indexed for MEDLINE]Related articles

    4.

    Tissue-specific role of glycogen synthase kinase 3beta in glucose homeostasis and insulin action.

    Patel S, Doble BW, MacAulay K, Sinclair EM, Drucker DJ, Woodgett JR.

    Mol Cell Biol. 2008 Oct;28(20):6314-28. Epub 2008 Aug 11.PMID: 18694957 [PubMed - indexed for MEDLINE]Related articlesFree article

    5.

    Lack of evidence for a role of TRB3/NIPK as an inhibitor of PKB-mediated insulin signalling in primary hepatocytes.

    Iynedjian PB.

    Biochem J. 2005 Feb 15;386(Pt 1):113-8.PMID: 15469416 [PubMed - indexed for MEDLINE]Related articlesFree article

    6.

    TRIB3 R84 variant is associated with impaired insulin-mediated nitric oxide production in human endothelial cells.

    Andreozzi F, Formoso G, Prudente S, Hribal ML, Pandolfi A, Bellacchio E, Di Silvestre S, Trischitta V, Consoli A, Sesti G.

    Arterioscler Thromb Vasc Biol. 2008 Jul;28(7):1355-60. Epub 2008 Apr 24.PMID: 18436806 [PubMed - indexed for MEDLINE]Related articlesFree article

    7.

    Effect of TRB3 on insulin and nutrient-stimulated hepatic p70 S6 kinase activity.

    Matsushima R, Harada N, Webster NJ, Tsutsumi YM, Nakaya Y.

    J Biol Chem. 2006 Oct 6;281(40):29719-29. Epub 2006 Aug 3.PMID: 16887816 [PubMed - indexed for MEDLINE]Related articlesFree article

    8.

    Skeletal muscle-selective knockout of LKB1 increases insulin sensitivity, improves glucose homeostasis, and decreases TRB3.

    Koh HJ, Arnolds DE, Fujii N, Tran TT, Rogers MJ, Jessen N, Li Y, Liew CW, Ho RC, Hirshman MF, Kulkarni RN, Kahn CR, Goodyear LJ.

    Mol Cell Biol. 2006 Nov;26(22):8217-27. Epub 2006 Sep 11.PMID: 16966378 [PubMed - indexed for MEDLINE]Related articlesFree article

    9.

    Caveolin-3 knockout mice show increased adiposity and whole body insulin resistance, with ligand-induced insulin receptor instability in skeletal muscle.

    Capozza F, Combs TP, Cohen AW, Cho YR, Park SY, Schubert W, Williams TM, Brasaemle DL, Jelicks LA, Scherer PE, Kim JK, Lisanti MP.

    Am J Physiol Cell Physiol. 2005 Jun;288(6):C1317-31. Epub 2005 Feb 2.PMID: 15689413 [PubMed - indexed for MEDLINE]Related articlesFree article

    10.

    Hepatic insulin resistance induced by prenatal alcohol exposure is associated with reduced PTEN and TRB3 acetylation in adult rat offspring.

    Yao XH, Nyomba BL.

    Am J Physiol Regul Integr Comp Physiol. 2008 Jun;294(6):R1797-806. Epub 2008 Apr 2.PMID: 18385463 [PubMed - indexed for MEDLINE]Related articles

    11.

    Impact of transgenic overexpression of SH2-containing inositol 5'-phosphatase 2 on glucose metabolism and insulin signaling in mice.

    Kagawa S, Soeda Y, Ishihara H, Oya T, Sasahara M, Yaguchi S, Oshita R, Wada T, Tsuneki H, Sasaoka T.

    Endocrinology. 2008 Feb;149(2):642-50. Epub 2007 Nov 26.PMID: 18039790 [PubMed - indexed for MEDLINE]Related articlesFree article

    12.

    Ghrelin enhances in vivo skeletal muscle but not liver AKT signaling in rats.

    Barazzoni R, Zanetti M, Cattin MR, Visintin L, Vinci P, Cattin L, Stebel M, Guarnieri G.

    Obesity (Silver Spring). 2007 Nov;15(11):2614-23.PMID: 18070752 [PubMed - indexed for MEDLINE]Related articles

    13.

    Muscle-specific deletion of rictor impairs insulin-stimulated glucose transport and enhances Basal glycogen synthase activity.

    Kumar A, Harris TE, Keller SR, Choi KM, Magnuson MA, Lawrence JC Jr.

    Mol Cell Biol. 2008 Jan;28(1):61-70. Epub 2007 Oct 29.PMID: 17967879 [PubMed - indexed for MEDLINE]Related articlesFree article

    14.

    Liver-specific deletion of insulin receptor substrate 2 does not impair hepatic glucose and lipid metabolism in mice.

    Simmgen M, Knauf C, Lopez M, Choudhury AI, Charalambous M, Cantley J, Bedford DC, Claret M, Iglesias MA, Heffron H, Cani PD, Vidal-Puig A, Burcelin R, Withers DJ.

    Diabetologia. 2006 Mar;49(3):552-61. Epub 2006 Jan 11.PMID: 16404553 [PubMed - indexed for MEDLINE]Related articles

    15.

    Dual effect of the adapter growth factor receptor-bound protein 14 (grb14) on insulin action in primary hepatocytes.

    Carré N, Caüzac M, Girard J, Burnol AF.

    Endocrinology. 2008 Jun;149(6):3109-17. Epub 2008 Mar 13.PMID: 18339716 [PubMed - indexed for MEDLINE]Related articlesFree article

    16.

    Analysis of hepatic gene transcription in mice expressing insulin-insensitive GSK3.

    Lipina C, Huang X, Finlay D, McManus EJ, Alessi DR, Sutherland C.

    Biochem J. 2005 Dec 15;392(Pt 3):633-9.PMID: 16176184 [PubMed - indexed for MEDLINE]Related articlesFree article

    17.

    L-glutamine supplementation induces insulin resistance in adipose tissue and improves insulin signalling in liver and muscle of rats with diet-induced obesity.

    Prada PO, Hirabara SM, de Souza CT, Schenka AA, Zecchin HG, Vassallo J, Velloso LA, Carneiro E, Carvalheira JB, Curi R, Saad MJ.

    Diabetologia. 2007 Sep;50(9):1949-59. Epub 2007 Jun 29.PMID: 17604977 [PubMed - indexed for MEDLINE]Related articles

    18.

    Glycogen synthase kinase 3alpha-specific regulation of murine hepatic glycogen metabolism.

    MacAulay K, Doble BW, Patel S, Hansotia T, Sinclair EM, Drucker DJ, Nagy A, Woodgett JR.

    Cell Metab. 2007 Oct;6(4):329-37.PMID: 17908561 [PubMed - indexed for MEDLINE]Related articles

    19.

    Continuous fat oxidation in acetyl-CoA carboxylase 2 knockout mice increases total energy expenditure, reduces fat mass, and improves insulin sensitivity.

    Choi CS, Savage DB, Abu-Elheiga L, Liu ZX, Kim S, Kulkarni A, Distefano A, Hwang YJ, Reznick RM, Codella R, Zhang D, Cline GW, Wakil SJ, Shulman GI.

    Proc Natl Acad Sci U S A. 2007 Oct 16;104(42):16480-5. Epub 2007 Oct 8.PMID: 17923673 [PubMed - indexed for MEDLINE]Related articlesFree article

    20.

    Suppression of hepatic glucose production by human neutrophil alpha-defensins through a signaling pathway distinct from insulin.

    Liu HY, Collins QF, Moukdar F, Zhuo D, Han J, Hong T, Collins S, Cao W.

    J Biol Chem. 2008 May 2;283(18):12056-63. Epub 2008 Mar 17.PMID: 18347011 [PubMed - indexed for MEDLINE]Related articlesFree article

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