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Progranulin in frontotemporal lobar degeneration and neuroinflammation.

Ahmed Z, Mackenzie IR, Hutton ML, Dickson DW.

J Neuroinflammation. 2007 Feb 11;4:7. Review.PMID: 17291356 [PubMed - indexed for MEDLINE]Free PMC ArticleFree textRelated citations

Progranulin: normal function and role in neurodegeneration.

Eriksen JL, Mackenzie IR.

J Neurochem. 2008 Jan;104(2):287-97. Epub 2007 Oct 22. Review.PMID: 17953663 [PubMed - indexed for MEDLINE]Related citations

Loss of progranulin function in frontotemporal lobar degeneration.

Cruts M, Van Broeckhoven C.

Trends Genet. 2008 Apr;24(4):186-94. Epub 2008 Mar 6. Review.PMID: 18328591 [PubMed - indexed for MEDLINE]Related citations

Mutations in progranulin are a major cause of ubiquitin-positive frontotemporal lobar degeneration.

Gass J, Cannon A, Mackenzie IR, Boeve B, Baker M, Adamson J, Crook R, Melquist S, Kuntz K, Petersen R, Josephs K, Pickering-Brown SM, Graff-Radford N, Uitti R, Dickson D, Wszolek Z, Gonzalez J, Beach TG, Bigio E, Johnson N, Weintraub S, Mesulam M, White CL 3rd, Woodruff B, Caselli R, Hsiung GY, Feldman H, Knopman D, Hutton M, Rademakers R.

Hum Mol Genet. 2006 Oct 15;15(20):2988-3001. Epub 2006 Sep 1.PMID: 16950801 [PubMed - indexed for MEDLINE]Free ArticleRelated citations

Pathogenic cysteine mutations affect progranulin function and production of mature granulins.

Wang J, Van Damme P, Cruchaga C, Gitcho MA, Vidal JM, Seijo-Martínez M, Wang L, Wu JY, Robberecht W, Goate A.

J Neurochem. 2010 Mar;112(5):1305-15. Epub 2009 Dec 17.PMID: 20028451 [PubMed - indexed for MEDLINE]Related citations

Deletion of the progranulin gene in patients with frontotemporal lobar degeneration or Parkinson disease.

Rovelet-Lecrux A, Deramecourt V, Legallic S, Maurage CA, Le Ber I, Brice A, Lambert JC, Frébourg T, Hannequin D, Pasquier F, Campion D.

Neurobiol Dis. 2008 Jul;31(1):41-5. Epub 2008 Apr 7.PMID: 18479928 [PubMed - indexed for MEDLINE]Related citations

Progranulin functions as a neurotrophic factor to regulate neurite outgrowth and enhance neuronal survival.

Van Damme P, Van Hoecke A, Lambrechts D, Vanacker P, Bogaert E, van Swieten J, Carmeliet P, Van Den Bosch L, Robberecht W.

J Cell Biol. 2008 Apr 7;181(1):37-41. Epub 2008 Mar 31.PMID: 18378771 [PubMed - indexed for MEDLINE]Free PMC ArticleFree textRelated citations

Neuropathologic features of frontotemporal lobar degeneration with ubiquitin-positive inclusions with progranulin gene (PGRN) mutations.

Josephs KA, Ahmed Z, Katsuse O, Parisi JF, Boeve BF, Knopman DS, Petersen RC, Davies P, Duara R, Graff-Radford NR, Uitti RJ, Rademakers R, Adamson J, Baker M, Hutton ML, Dickson DW.

J Neuropathol Exp Neurol. 2007 Feb;66(2):142-51.PMID: 17278999 [PubMed - indexed for MEDLINE]Related citations

Mutations in progranulin gene: clinical, pathological, and ribonucleic acid expression findings.

López de Munain A, Alzualde A, Gorostidi A, Otaegui D, Ruiz-Martínez J, Indakoetxea B, Ferrer I, Pérez-Tur J, Sáenz A, Bergareche A, Barandiarán M, Poza JJ, Zabalza R, Ruiz I, Urtasun M, Fernández-Manchola I, Olasagasti B, Espinal JB, Olaskoaga J, Ruibal M, Moreno F, Carrera N, Massó JF.

Biol Psychiatry. 2008 May 15;63(10):946-52. Epub 2007 Oct 22.PMID: 17950702 [PubMed - indexed for MEDLINE]Related citations

Frequency and clinical characteristics of progranulin mutation carriers in the Manchester frontotemporal lobar degeneration cohort: comparison with patients with MAPT and no known mutations.

Pickering-Brown SM, Rollinson S, Du Plessis D, Morrison KE, Varma A, Richardson AM, Neary D, Snowden JS, Mann DM.

Brain. 2008 Mar;131(Pt 3):721-31. Epub 2008 Jan 11.PMID: 18192287 [PubMed - indexed for MEDLINE]Free ArticleRelated citations

Progranulin mutations in ubiquitin-positive frontotemporal dementia linked to chromosome 17q21.

Cruts M, Kumar-Singh S, Van Broeckhoven C.

Curr Alzheimer Res. 2006 Dec;3(5):485-91. Review.PMID: 17168647 [PubMed - indexed for MEDLINE]Related citations

Voxel-based morphometry in frontotemporal lobar degeneration with ubiquitin-positive inclusions with and without progranulin mutations.

Whitwell JL, Jack CR Jr, Baker M, Rademakers R, Adamson J, Boeve BF, Knopman DS, Parisi JF, Petersen RC, Dickson DW, Hutton ML, Josephs KA.

Arch Neurol. 2007 Mar;64(3):371-6.PMID: 17353379 [PubMed - indexed for MEDLINE]Free PMC ArticleFree textRelated citations

Roles of progranulin in sexual differentiation of the developing brain and adult neurogenesis.

Suzuki M, Lee HC, Kayasuga Y, Chiba S, Nedachi T, Matsuwaki T, Yamanouchi K, Nishihara M.

J Reprod Dev. 2009 Aug;55(4):351-5. Review.PMID: 19721334 [PubMed - indexed for MEDLINE]Free PMC ArticleFree textRelated citations

Mutations other than null mutations producing a pathogenic loss of progranulin in frontotemporal dementia.

van der Zee J, Le Ber I, Maurer-Stroh S, Engelborghs S, Gijselinck I, Camuzat A, Brouwers N, Vandenberghe R, Sleegers K, Hannequin D, Dermaut B, Schymkowitz J, Campion D, Santens P, Martin JJ, Lacomblez L, De Pooter T, Peeters K, Mattheijssens M, Vercelletto M, Van den Broeck M, Cruts M, De Deyn PP, Rousseau F, Brice A, Van Broeckhoven C.

Hum Mutat. 2007 Apr;28(4):416.PMID: 17345602 [PubMed - indexed for MEDLINE]Related citations

Progranulin genetic variations in frontotemporal lobar degeneration: evidence for low mutation frequency in an Italian clinical series.

Borroni B, Archetti S, Alberici A, Agosti C, Gennarelli M, Bigni B, Bonvicini C, Ferrari M, Bellelli G, Galimberti D, Scarpini E, Di Lorenzo D, Caimi L, Caltagirone C, Di Luca M, Padovani A.

Neurogenetics. 2008 Jul;9(3):197-205. Epub 2008 Apr 8.PMID: 18392865 [PubMed - indexed for MEDLINE]Related citations

Traumatic brain injury may increase the risk for frontotemporal dementia through reduced progranulin.

Jawaid A, Rademakers R, Kass JS, Kalkonde Y, Schulz PE.

Neurodegener Dis. 2009;6(5-6):219-20. Epub 2010 Feb 10. Review.PMID: 20145419 [PubMed - indexed for MEDLINE]Related citations

The molecular genetics and neuropathology of frontotemporal lobar degeneration: recent developments.

Mackenzie IR, Rademakers R.

Neurogenetics. 2007 Nov;8(4):237-48. Epub 2007 Sep 6. Review.PMID: 17805587 [PubMed - indexed for MEDLINE]Related citations

Mutations in progranulin cause tau-negative frontotemporal dementia linked to chromosome 17.

Baker M, Mackenzie IR, Pickering-Brown SM, Gass J, Rademakers R, Lindholm C, Snowden J, Adamson J, Sadovnick AD, Rollinson S, Cannon A, Dwosh E, Neary D, Melquist S, Richardson A, Dickson D, Berger Z, Eriksen J, Robinson T, Zehr C, Dickey CA, Crook R, McGowan E, Mann D, Boeve B, Feldman H, Hutton M.

Nature. 2006 Aug 24;442(7105):916-9. Epub 2006 Jul 16.PMID: 16862116 [PubMed - indexed for MEDLINE]Related citations

Clinicopathologic correlation in PGRN mutations.

Davion S, Johnson N, Weintraub S, Mesulam MM, Engberg A, Mishra M, Baker M, Adamson J, Hutton M, Rademakers R, Bigio EH.

Neurology. 2007 Sep 11;69(11):1113-21. Epub 2007 May 23.PMID: 17522386 [PubMed - indexed for MEDLINE]Related citations

Granulin mutations associated with frontotemporal lobar degeneration and related disorders: an update.

Gijselinck I, Van Broeckhoven C, Cruts M.

Hum Mutat. 2008 Dec;29(12):1373-86.PMID: 18543312 [PubMed - indexed for MEDLINE]Related citations