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    Results: 1 to 20 of 251

    1.

    Impaired mitochondrial substrate oxidation in muscle of insulin-resistant offspring of type 2 diabetic patients.

    Befroy DE, Petersen KF, Dufour S, Mason GF, de Graaf RA, Rothman DL, Shulman GI.

    Diabetes. 2007 May;56(5):1376-81. Epub 2007 Feb 7.PMID: 17287462 [PubMed - indexed for MEDLINE]Related articlesFree article

    2.

    Decreased insulin-stimulated ATP synthesis and phosphate transport in muscle of insulin-resistant offspring of type 2 diabetic parents.

    Petersen KF, Dufour S, Shulman GI.

    PLoS Med. 2005 Sep;2(9):e233. Epub 2005 Aug 16.PMID: 16089501 [PubMed - indexed for MEDLINE]Related articlesFree article

    3.

    Impaired mitochondrial activity in the insulin-resistant offspring of patients with type 2 diabetes.

    Petersen KF, Dufour S, Befroy D, Garcia R, Shulman GI.

    N Engl J Med. 2004 Feb 12;350(7):664-71.PMID: 14960743 [PubMed - indexed for MEDLINE]Related articlesFree article

    4.

    Reduced mitochondrial density and increased IRS-1 serine phosphorylation in muscle of insulin-resistant offspring of type 2 diabetic parents.

    Morino K, Petersen KF, Dufour S, Befroy D, Frattini J, Shatzkes N, Neschen S, White MF, Bilz S, Sono S, Pypaert M, Shulman GI.

    J Clin Invest. 2005 Dec;115(12):3587-93. Epub 2005 Nov 10.PMID: 16284649 [PubMed - indexed for MEDLINE]Related articlesFree article

    5.

    Association of increased intramyocellular lipid content with insulin resistance in lean nondiabetic offspring of type 2 diabetic subjects.

    Jacob S, Machann J, Rett K, Brechtel K, Volk A, Renn W, Maerker E, Matthaei S, Schick F, Claussen CD, Häring HU.

    Diabetes. 1999 May;48(5):1113-9.PMID: 10331418 [PubMed - indexed for MEDLINE]Related articlesFree article

    6.

    Intramyocellular triglyceride content is a determinant of in vivo insulin resistance in humans: a 1H-13C nuclear magnetic resonance spectroscopy assessment in offspring of type 2 diabetic parents.

    Perseghin G, Scifo P, De Cobelli F, Pagliato E, Battezzati A, Arcelloni C, Vanzulli A, Testolin G, Pozza G, Del Maschio A, Luzi L.

    Diabetes. 1999 Aug;48(8):1600-6.PMID: 10426379 [PubMed - indexed for MEDLINE]Related articlesFree article

    7.

    Mitochondrial oxidative function and type 2 diabetes.

    Rabøl R, Boushel R, Dela F.

    Appl Physiol Nutr Metab. 2006 Dec;31(6):675-83. Review.PMID: 17213881 [PubMed - indexed for MEDLINE]Related articles

    8.

    Molecular mechanisms of insulin resistance in humans and their potential links with mitochondrial dysfunction.

    Morino K, Petersen KF, Shulman GI.

    Diabetes. 2006 Dec;55 Suppl 2:S9-S15. Review.PMID: 17130651 [PubMed - indexed for MEDLINE]Related articlesFree article

    9.

    Reduced whole-body lipid oxidation is associated with insulin resistance, but not with intramyocellular lipid content in offspring of type 2 diabetic patients.

    Lattuada G, Costantino F, Caumo A, Scifo P, Ragogna F, De Cobelli F, Del Maschio A, Luzi L, Perseghin G.

    Diabetologia. 2005 Apr;48(4):741-7. Epub 2005 Mar 10.PMID: 15759111 [PubMed - indexed for MEDLINE]Related articles

    10.

    Impaired in vivo mitochondrial function but similar intramyocellular lipid content in patients with type 2 diabetes mellitus and BMI-matched control subjects.

    Schrauwen-Hinderling VB, Kooi ME, Hesselink MK, Jeneson JA, Backes WH, van Echteld CJ, van Engelshoven JM, Mensink M, Schrauwen P.

    Diabetologia. 2007 Jan;50(1):113-20. Epub 2006 Nov 9.PMID: 17093944 [PubMed - indexed for MEDLINE]Related articles

    11.

    Increased intramyocellular lipid content but normal skeletal muscle mitochondrial oxidative capacity throughout the pathogenesis of type 2 diabetes.

    De Feyter HM, Lenaers E, Houten SM, Schrauwen P, Hesselink MK, Wanders RJ, Nicolay K, Prompers JJ.

    FASEB J. 2008 Nov;22(11):3947-55. Epub 2008 Jul 24.PMID: 18653763 [PubMed - indexed for MEDLINE]Related articlesFree article

    12.

    Defects in insulin secretion and insulin action in non-insulin-dependent diabetes mellitus are inherited. Metabolic studies on offspring of diabetic probands.

    Vauhkonen I, Niskanen L, Vanninen E, Kainulainen S, Uusitupa M, Laakso M.

    J Clin Invest. 1998 Jan 1;101(1):86-96.PMID: 9421470 [PubMed - indexed for MEDLINE]Related articlesFree article

    13.

    Muscle mitochondrial ATP synthesis and glucose transport/phosphorylation in type 2 diabetes.

    Szendroedi J, Schmid AI, Chmelik M, Toth C, Brehm A, Krssak M, Nowotny P, Wolzt M, Waldhausl W, Roden M.

    PLoS Med. 2007 May;4(5):e154.PMID: 17472434 [PubMed - indexed for MEDLINE]Related articlesFree article

    14.

    Type 2 diabetes mellitus and skeletal muscle metabolic function.

    Phielix E, Mensink M.

    Physiol Behav. 2008 May 23;94(2):252-8. Epub 2008 Jan 31. Review.PMID: 18342897 [PubMed - indexed for MEDLINE]Related articles

    15.

    Etiology of insulin resistance.

    Petersen KF, Shulman GI.

    Am J Med. 2006 May;119(5 Suppl 1):S10-6. Review.PMID: 16563942 [PubMed - indexed for MEDLINE]Related articles

    16.

    Early or advanced stage type 2 diabetes is not accompanied by in vivo skeletal muscle mitochondrial dysfunction.

    De Feyter HM, van den Broek NM, Praet SF, Nicolay K, van Loon LJ, Prompers JJ.

    Eur J Endocrinol. 2008 May;158(5):643-53.PMID: 18426822 [PubMed - indexed for MEDLINE]Related articlesFree article

    17.

    Impact of exercise training on insulin sensitivity, physical fitness, and muscle oxidative capacity in first-degree relatives of type 2 diabetic patients.

    Østergård T, Andersen JL, Nyholm B, Lund S, Nair KS, Saltin B, Schmitz O.

    Am J Physiol Endocrinol Metab. 2006 May;290(5):E998-1005. Epub 2005 Dec 13.PMID: 16352678 [PubMed - indexed for MEDLINE]Related articlesFree article

    18.

    [In-vivo 1H-MR spectroscopy: the determination of the intra- and extramyocellular lipid content depending on the insulin effect in the direct offspring of type-2 diabetics]

    Brechtel K, Machann J, Jacob S, Strempfer A, Schick F, Häring HU, Claussen CD.

    Rofo. 1999 Aug;171(2):113-20. German. PMID: 10506884 [PubMed - indexed for MEDLINE]Related articles

    19.

    Increased malonyl-CoA levels in muscle from obese and type 2 diabetic subjects lead to decreased fatty acid oxidation and increased lipogenesis; thiazolidinedione treatment reverses these defects.

    Bandyopadhyay GK, Yu JG, Ofrecio J, Olefsky JM.

    Diabetes. 2006 Aug;55(8):2277-85.PMID: 16873691 [PubMed - indexed for MEDLINE]Related articlesFree article

    20.

    Postabsorptive and insulin-stimulated energy homeostasis and leucine turnover in offspring of type 2 diabetic patients.

    Lattuada G, Sereni LP, Ruggieri D, Scollo A, Benedini S, Ragogna F, Costantino F, Battezzati A, Luzi L, Perseghin G.

    Diabetes Care. 2004 Nov;27(11):2716-22.PMID: 15505010 [PubMed - indexed for MEDLINE]Related articlesFree article

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