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    Results: 1 to 20 of 134

    1.

    Novel insights into the regulation of the bound and diffusible glucokinase in MIN6 beta-cells.

    Baltrusch S, Lenzen S.

    Diabetes. 2007 May;56(5):1305-15. Epub 2007 Feb 7.PMID: 17287461 [PubMed - indexed for MEDLINE]Related articlesFree article

    2.

    Monitoring of glucose-regulated single insulin secretory granule movement by selective photoactivation.

    Baltrusch S, Lenzen S.

    Diabetologia. 2008 Jun;51(6):989-96. Epub 2008 Apr 4.PMID: 18389213 [PubMed - indexed for MEDLINE]Related articles

    3.

    A role for PFK-2/FBPase-2, as distinct from fructose 2,6-bisphosphate, in regulation of insulin secretion in pancreatic beta-cells.

    Arden C, Hampson LJ, Huang GC, Shaw JA, Aldibbiat A, Holliman G, Manas D, Khan S, Lange AJ, Agius L.

    Biochem J. 2008 Apr 1;411(1):41-51.PMID: 18039179 [PubMed - indexed for MEDLINE]Related articlesFree article

    4.

    Metabolic regulation, activity state, and intracellular binding of glucokinase in insulin-secreting cells.

    Tiedge M, Steffeck H, Elsner M, Lenzen S.

    Diabetes. 1999 Mar;48(3):514-23.PMID: 10078551 [PubMed - indexed for MEDLINE]Related articlesFree article

    5.

    Glucokinase is an integral component of the insulin granules in glucose-responsive insulin secretory cells and does not translocate during glucose stimulation.

    Arden C, Harbottle A, Baltrusch S, Tiedge M, Agius L.

    Diabetes. 2004 Sep;53(9):2346-52.PMID: 15331544 [PubMed - indexed for MEDLINE]Related articlesFree article

    6.

    Fluorescence correlation spectroscopy investigation of a GFP mutant-enhanced cyan fluorescent protein and its tubulin fusion in living cells with two-photon excitation.

    Wang Z, Shah JV, Chen Z, Sun CH, Berns MW.

    J Biomed Opt. 2004 Mar-Apr;9(2):395-403.PMID: 15065907 [PubMed - indexed for MEDLINE]Related articles

    7.

    Regulation of beta cell glucokinase by S-nitrosylation and association with nitric oxide synthase.

    Rizzo MA, Piston DW.

    J Cell Biol. 2003 Apr 28;161(2):243-8. Epub 2003 Apr 21.PMID: 12707306 [PubMed - indexed for MEDLINE]Related articlesFree article

    8.

    A functional link between glucokinase binding to insulin granules and conformational alterations in response to glucose and insulin.

    Rizzo MA, Magnuson MA, Drain PF, Piston DW.

    J Biol Chem. 2002 Sep 13;277(37):34168-75. Epub 2002 Jul 5.PMID: 12101177 [PubMed - indexed for MEDLINE]Related articlesFree article

    9.

    Site of docking and fusion of insulin secretory granules in live MIN6 beta cells analyzed by TAT-conjugated anti-syntaxin 1 antibody and total internal reflection fluorescence microscopy.

    Ohara-Imaizumi M, Nishiwaki C, Kikuta T, Kumakura K, Nakamichi Y, Nagamatsu S.

    J Biol Chem. 2004 Feb 27;279(9):8403-8. Epub 2003 Dec 15.PMID: 14676208 [PubMed - indexed for MEDLINE]Related articlesFree article

    10.

    Kinetics of insulin secretion from MIN6 pseudoislets after encapsulation in a prototype device of a bioartificial pancreas.

    Barrientos R, Baltrusch S, Sigrist S, Legeay G, Belcourt A, Lenzen S.

    Horm Metab Res. 2009 Jan;41(1):5-9. Epub 2008 Oct 14.PMID: 18855306 [PubMed - indexed for MEDLINE]Related articles

    11.

    Regulation of insulin secretion, glucokinase gene transcription and beta cell proliferation by adipocyte-derived Wnt signalling molecules.

    Schinner S, Ulgen F, Papewalis C, Schott M, Woelk A, Vidal-Puig A, Scherbaum WA.

    Diabetologia. 2008 Jan;51(1):147-54. Epub 2007 Nov 10.PMID: 17994217 [PubMed - indexed for MEDLINE]Related articles

    12.

    Subcellular localization, mobility, and kinetic activity of glucokinase in glucose-responsive insulin-secreting cells.

    Stubbs M, Aiston S, Agius L.

    Diabetes. 2000 Dec;49(12):2048-55.PMID: 11118006 [PubMed - indexed for MEDLINE]Related articlesFree article

    13.

    An improved cyan fluorescent protein variant useful for FRET.

    Rizzo MA, Springer GH, Granada B, Piston DW.

    Nat Biotechnol. 2004 Apr;22(4):445-9. Epub 2004 Feb 29.PMID: 14990965 [PubMed - indexed for MEDLINE]Related articles

    14.

    Monitoring of exocytosis and endocytosis of insulin secretory granules in the pancreatic beta-cell line MIN6 using pH-sensitive green fluorescent protein (pHluorin) and confocal laser microscopy.

    Ohara-Imaizumi M, Nakamichi Y, Tanaka T, Katsuta H, Ishida H, Nagamatsu S.

    Biochem J. 2002 Apr 1;363(Pt 1):73-80.PMID: 11903049 [PubMed - indexed for MEDLINE]Related articlesFree article

    15.

    Glucokinase activator PSN-GK1 displays enhanced antihyperglycaemic and insulinotropic actions.

    Fyfe MC, White JR, Taylor A, Chatfield R, Wargent E, Printz RL, Sulpice T, McCormack JG, Procter MJ, Reynet C, Widdowson PS, Wong-Kai-In P.

    Diabetologia. 2007 Jun;50(6):1277-87. Epub 2007 Apr 6.PMID: 17415548 [PubMed - indexed for MEDLINE]Related articles

    16.

    Co-transfection of GK and mhPINS genes into HepG2 cells confers glucose-stimulated insulin secretion.

    Zheng HT, Deng HC, Huang CJ, Lan NZ, Fang F, Jian R.

    Cytotherapy. 2007;9(6):580-6.PMID: 17852199 [PubMed - indexed for MEDLINE]Related articles

    17.

    Cell biology assessment of glucokinase mutations V62M and G72R in pancreatic beta-cells: evidence for cellular instability of catalytic activity.

    Arden C, Trainer A, de la Iglesia N, Scougall KT, Gloyn AL, Lange AJ, Shaw JA, Matschinsky FM, Agius L.

    Diabetes. 2007 Jul;56(7):1773-82. Epub 2007 Mar 27.PMID: 17389332 [PubMed - indexed for MEDLINE]Related articlesFree article

    18.

    Glucose-dependent modulation of insulin secretion and intracellular calcium ions by GKA50, a glucokinase activator.

    Johnson D, Shepherd RM, Gill D, Gorman T, Smith DM, Dunne MJ.

    Diabetes. 2007 Jun;56(6):1694-702. Epub 2007 Mar 14.PMID: 17360975 [PubMed - indexed for MEDLINE]Related articlesFree article

    19.

    On-line monitoring of apoptosis in insulin-secreting cells.

    Köhler M, Zaitsev SV, Zaitseva II, Leibiger B, Leibiger IB, Turunen M, Kapelioukh IL, Bakkman L, Appelskog IB, de Monvel JB, Imreh G, Berggren PO.

    Diabetes. 2003 Dec;52(12):2943-50.PMID: 14633855 [PubMed - indexed for MEDLINE]Related articlesFree article

    20.

    Improved metabolic stimulus for glucose-induced insulin secretion through GK and PFK-2/FBPase-2 coexpression in insulin-producing RINm5F cells.

    Baltrusch S, Langer S, Massa L, Tiedge M, Lenzen S.

    Endocrinology. 2006 Dec;147(12):5768-76. Epub 2006 Sep 15.PMID: 16980436 [PubMed - indexed for MEDLINE]Related articlesFree article