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The cause and pathogenesis of the eosinophilia-myalgia syndrome.

Varga J, Uitto J, Jimenez SA.

Ann Intern Med. 1992 Jan 15;116(2):140-7. Review.PMID: 1727618 [PubMed - indexed for MEDLINE]Related articles

L-tryptophan and the eosinophilia-myalgia syndrome: current understanding of the etiology and pathogenesis.

Varga J, Jimenez SA, Uitto J.

J Invest Dermatol. 1993 Jan;100(1):97S-105S. Review.PMID: 8423409 [PubMed - indexed for MEDLINE]Related articles

Pathogenesis of L-tryptophan eosinophilia myalgia syndrome.

Sternberg EM.

Adv Exp Med Biol. 1996;398:325-30. Review.PMID: 8906284 [PubMed - indexed for MEDLINE]Related articles

Enhanced collagen synthesis and transcription by peak E, a contaminant of L-tryptophan preparations associated with the eosinophilia myalgia syndrome epidemic.

Takagi H, Ochoa MS, Zhou L, Helfman T, Murata H, Falanga V.

J Clin Invest. 1995 Nov;96(5):2120-5.PMID: 7593596 [PubMed - indexed for MEDLINE]Related articlesFree article

The clinical spectrum of the eosinophilia-myalgia syndrome associated with L-tryptophan ingestion. Clinical features in 20 patients and aspects of pathophysiology.

Martin RW, Duffy J, Engel AG, Lie JT, Bowles CA, Moyer TP, Gleich GJ.

Ann Intern Med. 1990 Jul 15;113(2):124-34.PMID: 2360751 [PubMed - indexed for MEDLINE]Related articles

1,1'-Ethylidenebis(tryptophan) (Peak E) induces functional activation of human eosinophils and interleukin 5 production from T lymphocytes: association of eosinophilia-myalgia syndrome with a L-tryptophan contaminant.

Yamaoka KA, Miyasaka N, Inuo G, Saito I, Kolb JP, Fujita K, Kashiwazaki S.

J Clin Immunol. 1994 Jan;14(1):50-60.PMID: 8132737 [PubMed - indexed for MEDLINE]Related articles

["Eosinophilia-myalgia" syndrome due to L-tryptophan containing products. Cooperative evaluation of French Regional Centers of Pharmacovigilance. Analysis of 24 cases]

Castot A, Bidault I, Bournerias I, Carlier P, Efthymiou ML.

Therapie. 1991 Sep-Oct;46(5):355-65. French. PMID: 1754978 [PubMed - indexed for MEDLINE]Related articles

Eosinophilia-myalgia syndrome: a recent syndrome serving as an alert to new diseases ahead.

Sidransky H.

Mod Pathol. 1994 Sep;7(7):806-10. Review.PMID: 7824518 [PubMed - indexed for MEDLINE]Related articles

The eosinophilia-myalgia syndrome and eosinophilic fasciitis.

Jimenez SA, Varga J.

Curr Opin Rheumatol. 1991 Dec;3(6):986-94. Review.PMID: 1772754 [PubMed - indexed for MEDLINE]Related articles

Effect of L-tryptophan products on function of human eosinophils: investigation of the causal mechanisms of eosinophilia myalgia syndrome associated with L-tryptophan products.

Saito H, Miyamoto T.

Int Arch Allergy Immunol. 1996;111 Suppl 1:37-42.PMID: 8906111 [PubMed - indexed for MEDLINE]Related articles

A murine model of the eosinophilia-myalgia syndrome induced by 1,1'-ethylidenebis (L-tryptophan).

Silver RM, Ludwicka A, Hampton M, Ohba T, Bingel SA, Smith T, Harley RA, Maize J, Heyes MP.

J Clin Invest. 1994 Apr;93(4):1473-80.PMID: 8163652 [PubMed - indexed for MEDLINE]Related articlesFree article

Tryptophan contaminants associated with eosinophilia-myalgia syndrome. The Eosinophilia-Myalgia Studies of Oregon, New York and New Mexico.

Philen RM, Hill RH Jr, Flanders WD, Caudill SP, Needham L, Sewell L, Sampson EJ, Falk H, Kilbourne EM.

Am J Epidemiol. 1993 Aug 1;138(3):154-9.PMID: 8356958 [PubMed - indexed for MEDLINE]Related articles

1,1'-Ethylidenebis[L-tryptophan], an impurity in L-tryptophan associated with eosinophilia-myalgia syndrome, stimulates type I collagen gene expression in human fibroblasts in vitro.

Zangrilli JG, Mayeno AN, Vining V, Varga J.

Biochem Mol Biol Int. 1995 Nov;37(5):925-33.PMID: 8624499 [PubMed - indexed for MEDLINE]Related articles

Eosinophilia-myalgia syndrome associated with exposure to tryptophan from a single manufacturer.

Slutsker L, Hoesly FC, Miller L, Williams LP, Watson JC, Fleming DW.

JAMA. 1990 Jul 11;264(2):213-7.PMID: 2355442 [PubMed - indexed for MEDLINE]Related articles

L-tryptophan contaminant 'peak E' induces the release of IL-5 and IL-10 by peripheral blood mononuclear cells from patients with functional somatic syndromes.

Barth H, Klein R, Berg PA.

Clin Exp Immunol. 2001 Nov;126(2):187-92.PMID: 11703359 [PubMed - indexed for MEDLINE]Related articlesFree article

Eosinophil-active cytokine from mononuclear cells cultured with L-tryptophan products: an unexpected consequence of endotoxin contamination.

Kita H, Mayeno AN, Weyand CM, Goronzy JJ, Weiler DA, Lundy SK, Abrams JS, Gleich GJ.

J Allergy Clin Immunol. 1995 Jun;95(6):1261-7.PMID: 7797795 [PubMed - indexed for MEDLINE]Related articles

An investigation of the cause of the eosinophilia-myalgia syndrome associated with tryptophan use.

Belongia EA, Hedberg CW, Gleich GJ, White KE, Mayeno AN, Loegering DA, Dunnette SL, Pirie PL, MacDonald KL, Osterholm MT.

N Engl J Med. 1990 Aug 9;323(6):357-65.PMID: 2370887 [PubMed - indexed for MEDLINE]Related articles

Eosinophilia-myalgia syndrome in L-tryptophan-exposed patients.

Kamb ML, Murphy JJ, Jones JL, Caston JC, Nederlof K, Horney LF, Swygert LA, Falk H, Kilbourne EM.

JAMA. 1992 Jan 1;267(1):77-82.PMID: 1727200 [PubMed - indexed for MEDLINE]Related articles

Association of the eosinophilia-myalgia syndrome with the ingestion of tryptophan.

Hertzman PA, Blevins WL, Mayer J, Greenfield B, Ting M, Gleich GJ.

N Engl J Med. 1990 Mar 29;322(13):869-73.PMID: 2314421 [PubMed - indexed for MEDLINE]Related articles

EBT, a tryptophan contaminant associated with eosinophilia myalgia syndrome, is incorporated into proteins during translation as an amino acid analog.

Buss WC, Stepanek J, Bankhurst AD, Mayeno AN, Pastuszyn A, Peabody D.

Autoimmunity. 1996;25(1):33-45.PMID: 9161698 [PubMed - indexed for MEDLINE]Related articles