PubMed

Renal effects of S18886 (Terutroban), a TP receptor antagonist, in an experimental model of type 2 diabetes.

Sebeková K, Eifert T, Klassen A, Heidland A, Amann K.

Diabetes. 2007 Apr;56(4):968-74. Epub 2007 Jan 31.PMID: 17267764 [PubMed - indexed for MEDLINE]Related articlesFree article

The selective TP receptor antagonist, S18886 (terutroban), attenuates renal damage in the double transgenic rat model of hypertension.

Sebeková K, Ramuscak A, Boor P, Heidland A, Amann K.

Am J Nephrol. 2008;28(1):47-53. Epub 2007 Sep 21.PMID: 17890857 [PubMed - indexed for MEDLINE]Related articles

Negative effects of rofecoxib treatment on cardiac function after ischemia-reperfusion injury in APOE3Leiden mice are prevented by combined treatment with thromboxane prostanoid-receptor antagonist S18886 (terutroban).

van der Hoorn JW, Jukema JW, Bekkers ME, Princen HM, Corda S, Emeis JJ, Steendijk P.

Crit Care Med. 2008 Sep;36(9):2576-82.PMID: 18679128 [PubMed - indexed for MEDLINE]Related articles

The thromboxane receptor antagonist S18886 attenuates renal oxidant stress and proteinuria in diabetic apolipoprotein E-deficient mice.

Xu S, Jiang B, Maitland KA, Bayat H, Gu J, Nadler JL, Corda S, Lavielle G, Verbeuren TJ, Zuccollo A, Cohen RA.

Diabetes. 2006 Jan;55(1):110-9.PMID: 16380483 [PubMed - indexed for MEDLINE]Related articlesFree article

S18886, a selective TP receptor antagonist, inhibits development of atherosclerosis in rabbits.

Worth NF, Berry CL, Thomas AC, Campbell JH.

Atherosclerosis. 2005 Nov;183(1):65-73. Epub 2005 Jun 9.PMID: 15950232 [PubMed - indexed for MEDLINE]Related articles

The thromboxane receptor antagonist S18886 but not aspirin inhibits atherogenesis in apo E-deficient mice: evidence that eicosanoids other than thromboxane contribute to atherosclerosis.

Cayatte AJ, Du Y, Oliver-Krasinski J, Lavielle G, Verbeuren TJ, Cohen RA.

Arterioscler Thromb Vasc Biol. 2000 Jul;20(7):1724-8.PMID: 10894809 [PubMed - indexed for MEDLINE]Related articlesFree article

Regular moderate exercise reduces advanced glycation and ameliorates early diabetic nephropathy in obese Zucker rats.

Boor P, Celec P, Behuliak M, Grancic P, Kebis A, Kukan M, Pronayová N, Liptaj T, Ostendorf T, Sebeková K.

Metabolism. 2009 Nov;58(11):1669-77. Epub 2009 Jul 15.PMID: 19608208 [PubMed - indexed for MEDLINE]Related articles

Role of systolic blood pressureon the progression of kidney damage in an experimental model of type 2 diabetes mellitus, obesity, and hypertension (Zucker rats).

González-Albarrán O, Gómez O, Ruiz E, Vieitez P, García-Robles R.

Am J Hypertens. 2003 Nov;16(11 Pt 1):979-85.PMID: 14573338 [PubMed - indexed for MEDLINE]Related articles

The thromboxane A2 receptor antagonist S18886 prevents enhanced atherogenesis caused by diabetes mellitus.

Zuccollo A, Shi C, Mastroianni R, Maitland-Toolan KA, Weisbrod RM, Zang M, Xu S, Jiang B, Oliver-Krasinski JM, Cayatte AJ, Corda S, Lavielle G, Verbeuren TJ, Cohen RA.

Circulation. 2005 Nov 8;112(19):3001-8. Epub 2005 Oct 31.PMID: 16260636 [PubMed - indexed for MEDLINE]Related articlesFree article

Kidney involvement in a nongenetic rat model of type 2 diabetes.

Danda RS, Habiba NM, Rincon-Choles H, Bhandari BK, Barnes JL, Abboud HE, Pergola PE.

Kidney Int. 2005 Dec;68(6):2562-71.PMID: 16316331 [PubMed - indexed for MEDLINE]Related articles

Dietary flaxseed meal reduces proteinuria and ameliorates nephropathy in an animal model of type II diabetes mellitus.

Velasquez MT, Bhathena SJ, Ranich T, Schwartz AM, Kardon DE, Ali AA, Haudenschild CC, Hansen CT.

Kidney Int. 2003 Dec;64(6):2100-7.PMID: 14633132 [PubMed - indexed for MEDLINE]Related articles

Antithrombotic properties of the thromboxane A2/prostaglandin H2 receptor antagonist S18886 on prevention of platelet-dependent cyclic flow reductions in dogs.

Maalej N, Osman HE, Shanmuganayagam D, Shebuski RJ, Folts JD.

J Cardiovasc Pharmacol. 2005 May;45(5):389-95.PMID: 15821433 [PubMed - indexed for MEDLINE]Related articles

Atherosclerosis regression and TP receptor inhibition: effect of S18886 on plaque size and composition--a magnetic resonance imaging study.

Viles-Gonzalez JF, Fuster V, Corti R, Valdiviezo C, Hutter R, Corda S, Anand SX, Badimon JJ.

Eur Heart J. 2005 Aug;26(15):1557-61. Epub 2005 Feb 25.PMID: 15734766 [PubMed - indexed for MEDLINE]Related articlesFree article

Preclinical evaluation of S18886 in an experimental model of coronary arterial thrombosis.

Hong TT, Huang J, Driscoll E, Lucchesi BR.

J Cardiovasc Pharmacol. 2006 Nov;48(5):239-48.PMID: 17110806 [PubMed - indexed for MEDLINE]Related articles

ACE inhibitor and angiotensin type I receptor antagonist in combination reduce renal damage in obese Zucker rats.

Toblli JE, DeRosa G, Cao G, Piorno P, Pagano P.

Kidney Int. 2004 Jun;65(6):2343-59.PMID: 15149348 [PubMed - indexed for MEDLINE]Related articles

Protease administration decreases enhanced transforming growth factor-beta 1 content in isolated glomeruli of diabetic rats.

Paczek L, Gaciong Z, Bartlomiejczyk I, Sebekova K, Birkenmeier G, Heidland A.

Drugs Exp Clin Res. 2001;27(4):141-9.PMID: 11822224 [PubMed - indexed for MEDLINE]Related articles

Irbesartan lowers blood pressure and ameliorates renal injury in experimental non-insulin-dependent diabetes mellitus.

O'Donnell MP, Crary GS, Oda H, Kasiske BL, Powell JR, Keane WF.

Kidney Int Suppl. 1997 Dec;63:S218-20.PMID: 9407464 [PubMed - indexed for MEDLINE]Related articles

Effect of aerobic training on diabetic nephropathy in a rat model of type 2 diabetes mellitus.

Chiasera JM, Ward-Cook KM, McCune SA, Wardlaw GM.

Ann Clin Lab Sci. 2000 Oct;30(4):346-53.PMID: 11045758 [PubMed - indexed for MEDLINE]Related articles

A neutralizing VEGF antibody prevents glomerular hypertrophy in a model of obese type 2 diabetes, the Zucker diabetic fatty rat.

Schrijvers BF, Flyvbjerg A, Tilton RG, Lameire NH, De Vriese AS.

Nephrol Dial Transplant. 2006 Feb;21(2):324-9. Epub 2005 Oct 25.PMID: 16249198 [PubMed - indexed for MEDLINE]Related articlesFree article

Role for thromboxane A2 from glomerular thrombi in nephropathy with type 2 diabetic rats.

Okumura M, Imanishi M, Okamura M, Hosoi M, Okada N, Konishi Y, Morikawa T, Miura K, Nakatani T, Fujii S.

Life Sci. 2003 May 2;72(24):2695-705.PMID: 12679187 [PubMed - indexed for MEDLINE]Related articles