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    Results: 1 to 20 of 106

    1.

    Antibody-mediated delivery of IL-10 inhibits the progression of established collagen-induced arthritis.

    Trachsel E, Bootz F, Silacci M, Kaspar M, Kosmehl H, Neri D.

    Arthritis Res Ther. 2007;9(1):R9.

    PMID:
    17261171
    [PubMed - indexed for MEDLINE]
    Free PMC Article
    2.

    Preclinical characterization of DEKAVIL (F8-IL10), a novel clinical-stage immunocytokine which inhibits the progression of collagen-induced arthritis.

    Schwager K, Kaspar M, Bootz F, Marcolongo R, Paresce E, Neri D, Trachsel E.

    Arthritis Res Ther. 2009;11(5):R142. Epub 2009 Sep 25.

    PMID:
    19781067
    [PubMed - indexed for MEDLINE]
    Free PMC Article
    3.

    Synergistic therapeutic effects of a tumor targeting antibody fragment, fused to interleukin 12 and to tumor necrosis factor alpha.

    Halin C, Gafner V, Villani ME, Borsi L, Berndt A, Kosmehl H, Zardi L, Neri D.

    Cancer Res. 2003 Jun 15;63(12):3202-10.

    PMID:
    12810649
    [PubMed - indexed for MEDLINE]
    Free Article
    4.

    Murine IL-10 gene transfer inhibits established collagen-induced arthritis and reduces adenovirus-mediated inflammatory responses in mouse liver.

    Quattrocchi E, Dallman MJ, Dhillon AP, Quaglia A, Bagnato G, Feldmann M.

    J Immunol. 2001 May 15;166(10):5970-8.

    PMID:
    11342612
    [PubMed - indexed for MEDLINE]
    Free Article
    5.

    The antibody-mediated targeted delivery of interleukin-15 and GM-CSF to the tumor neovasculature inhibits tumor growth and metastasis.

    Kaspar M, Trachsel E, Neri D.

    Cancer Res. 2007 May 15;67(10):4940-8.

    PMID:
    17510424
    [PubMed - indexed for MEDLINE]
    Free Article
    6.

    Immune modulation of collagen-induced arthritis by intranasal cytokine gene delivery: a model for the therapy of rheumatoid arthritis.

    Woods AM, Thompson SJ, Wooley PH, Panayi G, Klavinskis LS.

    Arthritis Rheum. 2005 Dec;52(12):3761-71.

    PMID:
    16329091
    [PubMed - indexed for MEDLINE]
    Free Article
    7.

    Enhancement of the antitumor properties of interleukin-2 by its targeted delivery to the tumor blood vessel extracellular matrix.

    Carnemolla B, Borsi L, Balza E, Castellani P, Meazza R, Berndt A, Ferrini S, Kosmehl H, Neri D, Zardi L.

    Blood. 2002 Mar 1;99(5):1659-65.

    PMID:
    11861281
    [PubMed - indexed for MEDLINE]
    Free Article
    8.

    The targeted immunocytokine L19-IL2 efficiently inhibits the growth of orthotopic pancreatic cancer.

    Wagner K, Schulz P, Scholz A, Wiedenmann B, Menrad A.

    Clin Cancer Res. 2008 Aug 1;14(15):4951-60.

    PMID:
    18676770
    [PubMed - indexed for MEDLINE]
    Free Article
    9.

    A human mAb specific to oncofetal fibronectin selectively targets chronic skin inflammation in vivo.

    Trachsel E, Kaspar M, Bootz F, Detmar M, Neri D.

    J Invest Dermatol. 2007 Apr;127(4):881-6. Epub 2006 Dec 21.

    PMID:
    17185984
    [PubMed - indexed for MEDLINE]
    Free Article
    10.

    Amphoteric liposomes enable systemic antigen-presenting cell-directed delivery of CD40 antisense and are therapeutically effective in experimental arthritis.

    Andreakos E, Rauchhaus U, Stavropoulos A, Endert G, Wendisch V, Benahmed AS, Giaglis S, Karras J, Lee S, Gaus H, Bennett CF, Williams RO, Sideras P, Panzner S.

    Arthritis Rheum. 2009 Apr;60(4):994-1005.

    PMID:
    19333921
    [PubMed - indexed for MEDLINE]
    Free Article
    11.

    Complete eradication of human B-cell lymphoma xenografts using rituximab in combination with the immunocytokine L19-IL2.

    Schliemann C, Palumbo A, Zuberbühler K, Villa A, Kaspar M, Trachsel E, Klapper W, Menssen HD, Neri D.

    Blood. 2009 Mar 5;113(10):2275-83. Epub 2008 Nov 12.

    PMID:
    19005180
    [PubMed - indexed for MEDLINE]
    Free Article
    12.

    Interleukin-6 blockade suppresses autoimmune arthritis in mice by the inhibition of inflammatory Th17 responses.

    Fujimoto M, Serada S, Mihara M, Uchiyama Y, Yoshida H, Koike N, Ohsugi Y, Nishikawa T, Ripley B, Kimura A, Kishimoto T, Naka T.

    Arthritis Rheum. 2008 Dec;58(12):3710-9.

    PMID:
    19035481
    [PubMed - indexed for MEDLINE]
    Free Article
    13.

    Therapeutic effects of antibodies to tumor necrosis factor-alpha, interleukin-6 and cytotoxic T-lymphocyte antigen 4 immunoglobulin in mice with glucose-6-phosphate isomerase induced arthritis.

    Matsumoto I, Zhang H, Yasukochi T, Iwanami K, Tanaka Y, Inoue A, Goto D, Ito S, Tsutsumi A, Sumida T.

    Arthritis Res Ther. 2008;10(3):R66. Epub 2008 Jun 5.

    PMID:
    18534002
    [PubMed - indexed for MEDLINE]
    Free PMC Article
    14.

    Blockade of the interleukin-21/interleukin-21 receptor pathway ameliorates disease in animal models of rheumatoid arthritis.

    Young DA, Hegen M, Ma HL, Whitters MJ, Albert LM, Lowe L, Senices M, Wu PW, Sibley B, Leathurby Y, Brown TP, Nickerson-Nutter C, Keith JC Jr, Collins M.

    Arthritis Rheum. 2007 Apr;56(4):1152-63.

    PMID:
    17393408
    [PubMed - indexed for MEDLINE]
    Free Article
    15.

    Localized expression of an anti-TNF single-chain antibody prevents development of collagen-induced arthritis.

    Smith R, Tarner IH, Hollenhorst M, Lin C, Levicnik AU, Fathman CG, Nolan GP.

    Gene Ther. 2003 Aug;10(15):1248-57.

    PMID:
    12858190
    [PubMed - indexed for MEDLINE]
    16.

    IL-3 inhibits TNF-alpha-induced bone resorption and prevents inflammatory arthritis.

    Yogesha SD, Khapli SM, Srivastava RK, Mangashetti LS, Pote ST, Mishra GC, Wani MR.

    J Immunol. 2009 Jan 1;182(1):361-70.

    PMID:
    19109167
    [PubMed - indexed for MEDLINE]
    Free Article
    17.

    Anticytokine treatment of established type II collagen-induced arthritis in DBA/1 mice: a comparative study using anti-TNFalpha, anti-IL-1alpha/beta and IL-1Ra.

    Joosten LA, Helsen MM, van de Loo FA, van den Berg WB.

    Arthritis Rheum. 2008 Feb;58(2 Suppl):S110-22.

    PMID:
    18240201
    [PubMed - indexed for MEDLINE]
    Free Article
    18.

    A comparative study on intra-articular versus systemic gene electrotransfer in experimental arthritis.

    Khoury M, Bigey P, Louis-Plence P, Noel D, Rhinn H, Scherman D, Jorgensen C, Apparailly F.

    J Gene Med. 2006 Aug;8(8):1027-36.

    PMID:
    16733831
    [PubMed - indexed for MEDLINE]
    19.

    Therapeutic effect of neutralizing endogenous IL-18 activity in the collagen-induced model of arthritis.

    Plater-Zyberk C, Joosten LA, Helsen MM, Sattonnet-Roche P, Siegfried C, Alouani S, van De Loo FA, Graber P, Aloni S, Cirillo R, Lubberts E, Dinarello CA, van Den Berg WB, Chvatchko Y.

    J Clin Invest. 2001 Dec;108(12):1825-32.

    PMID:
    11748266
    [PubMed - indexed for MEDLINE]
    Free PMC Article
    20.

    Inhibition of interleukin-33 signaling attenuates the severity of experimental arthritis.

    Palmer G, Talabot-Ayer D, Lamacchia C, Toy D, Seemayer CA, Viatte S, Finckh A, Smith DE, Gabay C.

    Arthritis Rheum. 2009 Mar;60(3):738-49.

    PMID:
    19248109
    [PubMed - indexed for MEDLINE]
    Free Article

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