PubMed

PTPN22 R620W functional variant in type 1 diabetes and autoimmunity related traits.

Chelala C, Duchatelet S, Joffret ML, Bergholdt R, Dubois-Laforgue D, Ghandil P, Pociot F, Caillat-Zucman S, Timsit J, Julier C.

Diabetes. 2007 Feb;56(2):522-6.PMID: 17259401 [PubMed - indexed for MEDLINE]Related articlesFree article

The protein tyrosine phosphatase nonreceptor 22 (PTPN22) is associated with high GAD antibody titer in latent autoimmune diabetes in adults: Non Insulin Requiring Autoimmune Diabetes (NIRAD) Study 3.

Petrone A, Suraci C, Capizzi M, Giaccari A, Bosi E, Tiberti C, Cossu E, Pozzilli P, Falorni A, Buzzetti R; NIRAD Study Group.

Diabetes Care. 2008 Mar;31(3):534-8. Epub 2007 Dec 4.PMID: 18056891 [PubMed - indexed for MEDLINE]Related articlesFree article

Linkage proof for PTPN22, a rheumatoid arthritis susceptibility gene and a human autoimmunity gene.

Michou L, Lasbleiz S, Rat AC, Migliorini P, Balsa A, Westhovens R, Barrera P, Alves H, Pierlot C, Glikmans E, Garnier S, Dausset J, Vaz C, Fernandes M, Petit-Teixeira E, Lemaire I, Pascual-Salcedo D, Bombardieri S, Dequeker J, Radstake TR, Van Riel P, van de Putte L, Lopes-Vaz A, Prum B, Bardin T, Dieudé P, Cornélis F; European Consortium on Rheumatoid Arthritis Families.

Proc Natl Acad Sci U S A. 2007 Jan 30;104(5):1649-54. Epub 2007 Jan 19.PMID: 17237219 [PubMed - indexed for MEDLINE]Related articlesFree article

Association of the lymphoid tyrosine phosphatase R620W variant with rheumatoid arthritis, but not Crohn's disease, in Canadian populations.

van Oene M, Wintle RF, Liu X, Yazdanpanah M, Gu X, Newman B, Kwan A, Johnson B, Owen J, Greer W, Mosher D, Maksymowych W, Keystone E, Rubin LA, Amos CI, Siminovitch KA.

Arthritis Rheum. 2005 Jul;52(7):1993-8.PMID: 15986374 [PubMed - indexed for MEDLINE]Related articlesFree article

Lymphoid tyrosine phosphatase (LYP/PTPN22) Arg620Trp variant regulates insulin autoimmunity and progression to type 1 diabetes.

Hermann R, Lipponen K, Kiviniemi M, Kakko T, Veijola R, Simell O, Knip M, Ilonen J.

Diabetologia. 2006 Jun;49(6):1198-208. Epub 2006 Apr 14.PMID: 16614815 [PubMed - indexed for MEDLINE]Related articles

Association of the single nucleotide polymorphism C1858T of the PTPN22 gene with type 1 diabetes.

Ladner MB, Bottini N, Valdes AM, Noble JA.

Hum Immunol. 2005 Jan;66(1):60-4.PMID: 15620463 [PubMed - indexed for MEDLINE]Related articles

Susceptibility to type 1 diabetes conferred by the PTPN22 C1858T polymorphism in the Spanish population.

Santiago JL, Martínez A, de la Calle H, Fernández-Arquero M, Figueredo MA, de la Concha EG, Urcelay E.

BMC Med Genet. 2007 Aug 13;8:54.PMID: 17697317 [PubMed - indexed for MEDLINE]Related articlesFree article

Evaluation of the genetic association of the PTPN22 R620W polymorphism in familial and sporadic systemic lupus erythematosus.

Kaufman KM, Kelly JA, Herring BJ, Adler AJ, Glenn SB, Namjou B, Frank SG, Dawson SL, Bruner GR, James JA, Harley JB.

Arthritis Rheum. 2006 Aug;54(8):2533-40.PMID: 16868974 [PubMed - indexed for MEDLINE]Related articlesFree article

Genetic association between a lymphoid tyrosine phosphatase (PTPN22) and type 1 diabetes.

Zheng W, She JX.

Diabetes. 2005 Mar;54(3):906-8.PMID: 15734872 [PubMed - indexed for MEDLINE]Related articlesFree article

The PTPN22 C1858T functional polymorphism and autoimmune diseases--a meta-analysis.

Lee YH, Rho YH, Choi SJ, Ji JD, Song GG, Nath SK, Harley JB.

Rheumatology (Oxford). 2007 Jan;46(1):49-56. Epub 2006 Jun 7. Review.PMID: 16760194 [PubMed - indexed for MEDLINE]Related articlesFree article

No independent role of the -1123 G>C and+2740 A>G variants in the association of PTPN22 with type 1 diabetes and juvenile idiopathic arthritis in two Caucasian populations.

Cinek O, Hradsky O, Ahmedov G, Slavcev A, Kolouskova S, Kulich M, Sumnik Z.

Diabetes Res Clin Pract. 2007 May;76(2):297-303. Epub 2006 Sep 26.PMID: 17000021 [PubMed - indexed for MEDLINE]Related articles

Do non-HLA genes influence development of persistent islet autoimmunity and type 1 diabetes in children with high-risk HLA-DR,DQ genotypes?

Steck AK, Zhang W, Bugawan TL, Barriga KJ, Blair A, Erlich HA, Eisenbarth GS, Norris JM, Rewers MJ.

Diabetes. 2009 Apr;58(4):1028-33. Epub 2009 Feb 2.PMID: 19188433 [PubMed - indexed for MEDLINE]Related articlesFree article

Systematic search for single nucleotide polymorphisms in a lymphoid tyrosine phosphatase gene (PTPN22): association between a promoter polymorphism and type 1 diabetes in Asian populations.

Kawasaki E, Awata T, Ikegami H, Kobayashi T, Maruyama T, Nakanishi K, Shimada A, Uga M, Kurihara S, Kawabata Y, Tanaka S, Kanazawa Y, Lee I, Eguchi K.

Am J Med Genet A. 2006 Mar 15;140(6):586-93. Erratum in: Am J Med Genet A. 2007 Aug 1;143(15):18212-3. Uga, Mho [corrected to Uga, Miho]. PMID: 16470599 [PubMed - indexed for MEDLINE]Related articles

The PTPN22 R620W polymorphism associates with RF positive rheumatoid arthritis in a dose-dependent manner but not with HLA-SE status.

Lee AT, Li W, Liew A, Bombardier C, Weisman M, Massarotti EM, Kent J, Wolfe F, Begovich AB, Gregersen PK.

Genes Immun. 2005 Mar;6(2):129-33.PMID: 15674368 [PubMed - indexed for MEDLINE]Related articles

Replication of an association between the lymphoid tyrosine phosphatase locus (LYP/PTPN22) with type 1 diabetes, and evidence for its role as a general autoimmunity locus.

Smyth D, Cooper JD, Collins JE, Heward JM, Franklyn JA, Howson JM, Vella A, Nutland S, Rance HE, Maier L, Barratt BJ, Guja C, Ionescu-Tîrgoviste C, Savage DA, Dunger DB, Widmer B, Strachan DP, Ring SM, Walker N, Clayton DG, Twells RC, Gough SC, Todd JA.

Diabetes. 2004 Nov;53(11):3020-3.PMID: 15504986 [PubMed - indexed for MEDLINE]Related articlesFree article

Protein tyrosine phosphatase non-receptor type 22 (PTPN22) gene R620W variant and sporadic idiopathic hypoparathyroidism in Asian Indians.

Ray D, Tomar N, Gupta N, Goswami R.

Int J Immunogenet. 2006 Aug;33(4):237-40.PMID: 16893384 [PubMed - indexed for MEDLINE]Related articles

Lack of association between the protein tyrosine phosphatase non-receptor 22 (PTPN22)*620W allele and systemic sclerosis in the French Caucasian population.

Wipff J, Allanore Y, Kahan A, Meyer O, Mouthon L, Guillevin L, Pierlot C, Glikmans E, Bardin T, Boileau C, Cornélis F, Dieudé P.

Ann Rheum Dis. 2006 Sep;65(9):1230-2. Epub 2006 Feb 7.PMID: 16464986 [PubMed - indexed for MEDLINE]Related articlesFree article

Association between the PTPN22 gene and rheumatoid arthritis and juvenile idiopathic arthritis in a UK population: further support that PTPN22 is an autoimmunity gene.

Hinks A, Barton A, John S, Bruce I, Hawkins C, Griffiths CE, Donn R, Thomson W, Silman A, Worthington J.

Arthritis Rheum. 2005 Jun;52(6):1694-9.PMID: 15934099 [PubMed - indexed for MEDLINE]Related articlesFree article

A general autoimmunity gene (PTPN22) is not associated with inflammatory bowel disease in a British population.

Prescott NJ, Fisher SA, Onnie C, Pattni R, Steer S, Sanderson J, Forbes A, Lewis CM, Mathew CG.

Tissue Antigens. 2005 Oct;66(4):318-20.PMID: 16185328 [PubMed - indexed for MEDLINE]Related articles

A type 1 diabetes subgroup with a female bias is characterised by failure in tolerance to thyroid peroxidase at an early age and a strong association with the cytotoxic T-lymphocyte-associated antigen-4 gene.

Howson JM, Dunger DB, Nutland S, Stevens H, Wicker LS, Todd JA.

Diabetologia. 2007 Apr;50(4):741-6. Epub 2007 Feb 14.PMID: 17334650 [PubMed - indexed for MEDLINE]Related articlesFree article