PubMed

Tumor necrosis factor-alpha induces intestinal insulin resistance and stimulates the overproduction of intestinal apolipoprotein B48-containing lipoproteins.

Qin B, Qiu W, Avramoglu RK, Adeli K.

Diabetes. 2007 Feb;56(2):450-61.PMID: 17259391 [PubMed - indexed for MEDLINE]Related articlesFree article

Tumor necrosis factor-alpha directly stimulates the overproduction of hepatic apolipoprotein B100-containing VLDL via impairment of hepatic insulin signaling.

Qin B, Anderson RA, Adeli K.

Am J Physiol Gastrointest Liver Physiol. 2008 May;294(5):G1120-9. Epub 2008 Mar 27.PMID: 18372392 [PubMed - indexed for MEDLINE]Related articlesFree article

Intestinal insulin resistance and aberrant production of apolipoprotein B48 lipoproteins in an animal model of insulin resistance and metabolic dyslipidemia: evidence for activation of protein tyrosine phosphatase-1B, extracellular signal-related kinase, and sterol regulatory element-binding protein-1c in the fructose-fed hamster intestine.

Federico LM, Naples M, Taylor D, Adeli K.

Diabetes. 2006 May;55(5):1316-26.PMID: 16644688 [PubMed - indexed for MEDLINE]Related articlesFree article

Cinnamon extract attenuates TNF-alpha-induced intestinal lipoprotein ApoB48 overproduction by regulating inflammatory, insulin, and lipoprotein pathways in enterocytes.

Qin B, Dawson H, Polansky MM, Anderson RA.

Horm Metab Res. 2009 Jul;41(7):516-22.PMID: 19593846 [PubMed - indexed for MEDLINE]Related articles

Fasting and postprandial overproduction of intestinally derived lipoproteins in an animal model of insulin resistance. Evidence that chronic fructose feeding in the hamster is accompanied by enhanced intestinal de novo lipogenesis and ApoB48-containing lipoprotein overproduction.

Haidari M, Leung N, Mahbub F, Uffelman KD, Kohen-Avramoglu R, Lewis GF, Adeli K.

J Biol Chem. 2002 Aug 30;277(35):31646-55. Epub 2002 Jun 17.PMID: 12070142 [PubMed - indexed for MEDLINE]Related articlesFree article

Intestinal lipoprotein overproduction, a newly recognized component of insulin resistance, is ameliorated by the insulin sensitizer rosiglitazone: studies in the fructose-fed Syrian golden hamster.

Lewis GF, Uffelman K, Naples M, Szeto L, Haidari M, Adeli K.

Endocrinology. 2005 Jan;146(1):247-55. Epub 2004 Oct 14.PMID: 15486228 [PubMed - indexed for MEDLINE]Related articlesFree article

Intestinal assembly and secretion of highly dense/lipid-poor apolipoprotein B48-containing lipoprotein particles in the fasting state: evidence for induction by insulin resistance and exogenous fatty acids.

Guo Q, Avramoglu RK, Adeli K.

Metabolism. 2005 May;54(5):689-97.PMID: 15877301 [PubMed - indexed for MEDLINE]Related articles

Intestinal lipoprotein production is stimulated by an acute elevation of plasma free fatty acids in the fasting state: studies in insulin-resistant and insulin-sensitized Syrian golden hamsters.

Lewis GF, Naples M, Uffelman K, Leung N, Szeto L, Adeli K.

Endocrinology. 2004 Nov;145(11):5006-12. Epub 2004 Jul 22.PMID: 15271878 [PubMed - indexed for MEDLINE]Related articlesFree article

Rosiglitazone improves intestinal lipoprotein overproduction in the fat-fed Syrian Golden hamster, an animal model of nutritionally-induced insulin resistance.

Leung N, Naples M, Uffelman K, Szeto L, Adeli K, Lewis GF.

Atherosclerosis. 2004 Jun;174(2):235-41.PMID: 15136053 [PubMed - indexed for MEDLINE]Related articles

Tumor necrosis factor-alpha induces insulin resistance in endothelial cells via a p38 mitogen-activated protein kinase-dependent pathway.

Li G, Barrett EJ, Barrett MO, Cao W, Liu Z.

Endocrinology. 2007 Jul;148(7):3356-63. Epub 2007 Apr 19.PMID: 17446186 [PubMed - indexed for MEDLINE]Related articlesFree article

Treatment with atorvastatin ameliorates hepatic very-low-density lipoprotein overproduction in an animal model of insulin resistance, the fructose-fed Syrian golden hamster: evidence that reduced hypertriglyceridemia is accompanied by improved hepatic insulin sensitivity.

Mangaloglu L, Cheung RC, Van Iderstine SC, Taghibiglou C, Pontrelli L, Adeli K.

Metabolism. 2002 Apr;51(4):409-18.PMID: 11912545 [PubMed - indexed for MEDLINE]Related articles

Tumor necrosis factor alpha produces insulin resistance in skeletal muscle by activation of inhibitor kappaB kinase in a p38 MAPK-dependent manner.

de Alvaro C, Teruel T, Hernandez R, Lorenzo M.

J Biol Chem. 2004 Apr 23;279(17):17070-8. Epub 2004 Feb 4.PMID: 14764603 [PubMed - indexed for MEDLINE]Related articlesFree article

Mechanisms of hepatic very low density lipoprotein overproduction in insulin resistance. Evidence for enhanced lipoprotein assembly, reduced intracellular ApoB degradation, and increased microsomal triglyceride transfer protein in a fructose-fed hamster model.

Taghibiglou C, Carpentier A, Van Iderstine SC, Chen B, Rudy D, Aiton A, Lewis GF, Adeli K.

J Biol Chem. 2000 Mar 24;275(12):8416-25. Erratum in: J Biol Chem 2001 Jun 8;276(23):20804. PMID: 10722675 [PubMed - indexed for MEDLINE]Related articlesFree article

Cinnamon extract inhibits the postprandial overproduction of apolipoprotein B48-containing lipoproteins in fructose-fed animals.

Qin B, Polansky MM, Sato Y, Adeli K, Anderson RA.

J Nutr Biochem. 2009 Nov;20(11):901-8. Epub 2008 Nov 6.PMID: 18993048 [PubMed - in process]Related articles

Synergistic effect of TNF-alpha in soluble VCAM-1-induced angiogenesis through alpha 4 integrins.

Nakao S, Kuwano T, Ishibashi T, Kuwano M, Ono M.

J Immunol. 2003 Jun 1;170(11):5704-11.PMID: 12759453 [PubMed - indexed for MEDLINE]Related articlesFree article

p38 mitogen-activated protein kinase is activated and linked to TNF-alpha signaling in inflammatory bowel disease.

Waetzig GH, Seegert D, Rosenstiel P, Nikolaus S, Schreiber S.

J Immunol. 2002 May 15;168(10):5342-51.PMID: 11994493 [PubMed - indexed for MEDLINE]Related articlesFree article

Tumor necrosis factor-alpha induces mechanical allodynia after spinal nerve ligation by activation of p38 MAPK in primary sensory neurons.

Schäfers M, Svensson CI, Sommer C, Sorkin LS.

J Neurosci. 2003 Apr 1;23(7):2517-21.PMID: 12684435 [PubMed - indexed for MEDLINE]Related articlesFree article

Impaired postprandial apolipoprotein-B48 metabolism in the obese, insulin-resistant JCR:LA-cp rat: increased atherogenicity for the metabolic syndrome.

Vine DF, Takechi R, Russell JC, Proctor SD.

Atherosclerosis. 2007 Feb;190(2):282-90. Epub 2006 Apr 19.PMID: 16624317 [PubMed - indexed for MEDLINE]Related articles

Secretion of atherogenic risk factor apolipoprotein B-100 is increased by a potential mechanism of JNK/PKC-mediated insulin resistance in liver cells.

Jin UH, Kang YJ, Chang YC, Kim CH.

J Cell Biochem. 2008 Feb 15;103(3):908-19.PMID: 17647275 [PubMed - indexed for MEDLINE]Related articles

p38 MAPK mediates the regulation of alpha1(I) procollagen mRNA levels by TNF-alpha and TGF-beta in a cell line of rat hepatic stellate cells(1).

Varela-Rey M, Montiel-Duarte C, Osés-Prieto JA, López-Zabalza MJ, Jaffrèzou JP, Rojkind M, Iraburu MJ.

FEBS Lett. 2002 Sep 25;528(1-3):133-8.PMID: 12297293 [PubMed - indexed for MEDLINE]Related articles