PubMed

Cellular expression requirements for inhibition of type 1 diabetes by a dominantly protective major histocompatibility complex haplotype.

Chen YG, Silveira PA, Osborne MA, Chapman HD, Serreze DV.

Diabetes. 2007 Feb;56(2):424-30.PMID: 17259387 [PubMed - indexed for MEDLINE]Related articlesFree article

Inhibition of autoimmune diabetes in nonobese diabetic mice by transgenic restoration of H2-E MHC class II expression: additive, but unequal, involvement of multiple APC subtypes.

Johnson EA, Silveira P, Chapman HD, Leiter EH, Serreze DV.

J Immunol. 2001 Aug 15;167(4):2404-10.PMID: 11490031 [PubMed - indexed for MEDLINE]Related articlesFree article

MHC class II molecules play a role in the selection of autoreactive class I-restricted CD8 T cells that are essential contributors to type 1 diabetes development in nonobese diabetic mice.

Serreze DV, Holl TM, Marron MP, Graser RT, Johnson EA, Choisy-Rossi C, Slattery RM, Lieberman SM, DiLorenzo TP.

J Immunol. 2004 Jan 15;172(2):871-9.PMID: 14707058 [PubMed - indexed for MEDLINE]Related articlesFree article

T-cell tolerance by dendritic cells and macrophages as a mechanism for the major histocompatibility complex-linked resistance to autoimmune diabetes.

Thiessen S, Serra P, Amrani A, Verdaguer J, Santamaria P.

Diabetes. 2002 Feb;51(2):325-38.PMID: 11812739 [PubMed - indexed for MEDLINE]Related articlesFree article

A mechanism for the major histocompatibility complex-linked resistance to autoimmunity.

Schmidt D, Verdaguer J, Averill N, Santamaria P.

J Exp Med. 1997 Oct 6;186(7):1059-75.PMID: 9314555 [PubMed - indexed for MEDLINE]Related articlesFree article

Idd9/11 genetic locus regulates diabetogenic activity of CD4 T-cells in nonobese diabetic (NOD) mice.

Chen YG, Scheuplein F, Osborne MA, Tsaih SW, Chapman HD, Serreze DV.

Diabetes. 2008 Dec;57(12):3273-80. Epub 2008 Sep 5.PMID: 18776136 [PubMed - indexed for MEDLINE]Related articlesFree article

Development of diabetogenic T cells from NOD/Lt marrow is blocked when an allo-H-2 haplotype is expressed on cells of hemopoietic origin, but not on thymic epithelium.

Serreze DV, Leiter EH.

J Immunol. 1991 Aug 15;147(4):1222-9.PMID: 1869820 [PubMed - indexed for MEDLINE]Related articles

Major histocompatibility complex class II molecules can protect from diabetes by positively selecting T cells with additional specificities.

Lühder F, Katz J, Benoist C, Mathis D.

J Exp Med. 1998 Feb 2;187(3):379-87.PMID: 9449718 [PubMed - indexed for MEDLINE]Related articlesFree article

Partial versus full allogeneic hemopoietic chimerization is a preferential means to inhibit type 1 diabetes as the latter induces generalized immunosuppression.

Serreze DV, Osborne MA, Chen YG, Chapman HD, Pearson T, Brehm MA, Greiner DL.

J Immunol. 2006 Nov 15;177(10):6675-84.PMID: 17082580 [PubMed - indexed for MEDLINE]Related articlesFree article

Alleviation of insulitis in NOD mice is associated with expression of transgenic MHC E molecules on primary antigen-presenting cells.

Pilström B, Böhme J.

Immunology. 1997 Apr;90(4):483-8.PMID: 9176099 [PubMed - indexed for MEDLINE]Related articlesFree article

Defects in the differentiation and function of antigen presenting cells in NOD/Lt mice.

Serreze DV, Gaskins HR, Leiter EH.

J Immunol. 1993 Mar 15;150(6):2534-43.PMID: 8450229 [PubMed - indexed for MEDLINE]Related articles

"Humanized" HLA transgenic NOD mice to identify pancreatic beta cell autoantigens of potential clinical relevance to type 1 diabetes.

Serreze DV, Marron MP, Dilorenzo TP.

Ann N Y Acad Sci. 2007 Apr;1103:103-11. Epub 2007 Mar 21.PMID: 17376821 [PubMed - indexed for MEDLINE]Related articles

Two mechanisms for the non-MHC-linked resistance to spontaneous autoimmunity.

Verdaguer J, Amrani A, Anderson B, Schmidt D, Santamaria P.

J Immunol. 1999 Apr 15;162(8):4614-26.PMID: 10202001 [PubMed - indexed for MEDLINE]Related articlesFree article

Major histocompatibility complex-linked diabetes susceptibility in NOD/Lt mice: subcongenic analysis localizes a component of Idd16 at the H2-D end of the diabetogenic H2(g7) complex.

Pomerleau DP, Bagley RJ, Serreze DV, Mathews CE, Leiter EH.

Diabetes. 2005 May;54(5):1603-6.PMID: 15855353 [PubMed - indexed for MEDLINE]Related articlesFree article

Bone marrow expressing a diabetes resistance MHC class II allele: diabetes deviation by chronic immune stimulation.

Reifsnyder P, Schott W, Pomerleau D, Lessard MD, Soper BW, Leiter EH.

Novartis Found Symp. 2008;292:32-46; discussion 46-9, 122-9, 202-3.PMID: 19203091 [PubMed - indexed for MEDLINE]Related articles

Quantitative thresholds of MHC class II I-E expressed on hemopoietically derived antigen-presenting cells in transgenic NOD/Lt mice determine level of diabetes resistance and indicate mechanism of protection.

Hanson MS, Cetkovic-Cvrlje M, Ramiya VK, Atkinson MA, Maclaren NK, Singh B, Elliott JF, Serreze DV, Leiter EH.

J Immunol. 1996 Aug 1;157(3):1279-87.PMID: 8757636 [PubMed - indexed for MEDLINE]Related articles

Antigen presenting cells and the immunogenetics of autoimmune diabetes in NOD mice.

Leiter EH, Serreze DV.

Reg Immunol. 1992 Sep-Oct;4(5):263-73. Review.PMID: 1290746 [PubMed - indexed for MEDLINE]Related articles

Diabetes resistance/susceptibility in T cells of nonobese diabetic mice conferred by MHC and MHC-linked genes.

Ueno A, Cho S, Cheng L, Wang Z, Wang B, Yang Y.

J Immunol. 2005 Oct 15;175(8):5240-7.PMID: 16210629 [PubMed - indexed for MEDLINE]Related articlesFree article

B lymphocytes are essential for the initiation of T cell-mediated autoimmune diabetes: analysis of a new "speed congenic" stock of NOD.Ig mu null mice.

Serreze DV, Chapman HD, Varnum DS, Hanson MS, Reifsnyder PC, Richard SD, Fleming SA, Leiter EH, Shultz LD.

J Exp Med. 1996 Nov 1;184(5):2049-53.PMID: 8920894 [PubMed - indexed for MEDLINE]Related articlesFree article

MHC class I-mediated antigen presentation and induction of CD8+ cytotoxic T-cell responses in autoimmune diabetes-prone NOD mice.

Serreze DV, Gallichan WS, Snider DP, Croitoru K, Rosenthal KL, Leiter EH, Christianson GJ, Dudley ME, Roopenian DC.

Diabetes. 1996 Jul;45(7):902-8.PMID: 8666141 [PubMed - indexed for MEDLINE]Related articles